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Categories: Chemistry: Organic Chemistry, Geoscience: Landslides
Published This one-atom chemical reaction could transform drug discovery
(via sciencedaily.com) Researchers have used single carbon atom doping to form four chemical bonds in one step. Gamma-lactams (cyclic molecules that are common in antibiotics) were easily synthetically accessible from alpha, beta-unsaturated amides (an important molecule in cancer progression). The team chemically modified an anti-seizure medication in 96% yield, highlighting the work's utility to otherwise synthetically complex aspects of pharmaceutical development. The results of this work could become foundational to drug discovery and development.
Published Using CRISPR to detect cancer biomarkers
(via sciencedaily.com) Most cancer diagnostic techniques rely on uncomfortable and invasive procedures, such as biopsies, endoscopies or mammograms. Blood samples could be a less unpleasant option, though only a few forms of the disease can currently be diagnosed this way. But now, researchers have developed an easy-to-use method that can detect small amounts of cancer-related molecules in exosomes in plasma and effectively distinguish between malignant and benign samples.
Published Soil tainted by air pollution expels carbon
(via sciencedaily.com) New research suggests nitrogen released by gas-powered machines causes dry soil to let go of carbon and release it back into the atmosphere, where it can contribute to climate change.
Published 'Snapshots' of translation could help us investigate cellular proteins
(via sciencedaily.com) Original source Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like gene regulation has been greatly enhanced by the development of a process termed PETEOS -- short for peptidyl-tRNA enrichment using organic extraction and silica adsorption. This method allows for the large-scale harvesting, processing, and identification of pep-tRNA polypeptide moieties.
Published Catching the wrongdoers in the act: Chemists develop a novel tool to decipher bacterial infections in real time
(via sciencedaily.com) Original source A research team has developed a novel chemical tool to reveal how bacteria adapt to the host environment and control host cells. This tool can be used to investigate bacterial interactions with the host in real-time during an infection, which cannot be easily achieved by other methods.
Published A changing flood recipe for Las Vegas
(via sciencedaily.com) Las Vegas, with its rapid urbanization and desert landscape, is highly vulnerable to flooding. For this reason, flood managers have built an extensive system of drainage ditches and detention basins to protect the public. Now, a new study shows how intentional engineering and urban development are interacting with climate change to alter the timing and intensity of flood risk.
Published Most plastic debris on Seychelles beaches comes from far-off sources
(via sciencedaily.com) A new modelling study shows that the Seychelles and other islands in the western Indian Ocean are not responsible for most of the plastic waste that accumulates on their beaches. Indonesia, India, and Sri Lanka were found to be the main sources of land-based plastic debris. The Seychelles also accumulate significant amounts of plastic debris of marine origin from fisheries and shipping lanes. • The results highlight the urgent need for a legally-binding Global Plastics Treaty and greater enforcement of regional policies to reduce plastic waste.
Published Study shows landbuilding, site of freshwater diversion
(via sciencedaily.com) Supporters of the large-scale Mississippi River sediment diversions currently being planned by the Louisiana Coastal Protection and Restoration Authority got a boost to their case recently when scientists published an analysis of two existing freshwater diversions on the state's coastline, one of which shows a significant amount of land having formed over the past 17 years.
Published Landslide risk remains years after even a weak earthquake
(via sciencedaily.com) Satellite observations have revealed that weak seismic ground shaking can trigger powerful landslide acceleration -- even several years after a significant earthquake.
Published Satellites cast critical eye on coastal dead zones
(via sciencedaily.com) Scientists have found a new and better way to use remote sensing to understand where coastal dead zones are and predict changes.
Published Using 1980s environmental modeling to mitigate future disasters: Could Japan's 3/11 disaster have been prevented?
(via sciencedaily.com) On March 11, 2011, multiple catastrophes in Japan were triggered by the Great East Japan Earthquake, including the nuclear accident at the Fukushima Daiichi Nuclear Power Plant. This event, also known as the 3/11 disaster, is what is known as a compound disaster. Now that over a decade has passed since this event, researchers are investigating how to prevent the next compound disaster.
Published Report outlines plans for major research effort on subduction zone geologic hazards
(via sciencedaily.com) Subduction zones, where one tectonic plate slides beneath another, produce the most devastating seismic, volcanic, and landslide hazards on the planet. A new report presents an ambitious plan to make major advances in understanding subduction zone hazards by bringing together a diverse community of scientists in a long-term collaborative effort, deploying new instrumentation in subduction zones, and developing more sophisticated and accurate models.
Published Physics of disaster: How mudslides move
(via sciencedaily.com) A devastating fire followed by an intense rainstorm triggered mudslides in Southern California in 2018 that claimed 23 lives. New findings elucidate the physics behind the deadly disaster that may inform predictive models of future mudslides.
Published Seismic sensing reveals flood damage potential
(via sciencedaily.com) Rapidly evolving floods are a major and growing hazard worldwide. Currently, their onset and evolution is hard to identify using existing systems. However, seismic sensors already in place to detect earthquakes could be a solution to this problem. Researchers show that a seismometer can sense a flood, such as the devastating one that hit Germany in July 2021, up to 1.5 km away. This could act as an early warning to save lives and lessen damage. They also found that being able to measure the 'seismic footprint' of the flood provides information on its magnitude, velocity and trajectory in real time, which could be used for future flood protection.
Published Under pressure: Rethinking coastal land use and adaptation strategies
(via sciencedaily.com) Researchers recently published a study looking at land use changes from the past and the importance of taking factors such as socio-economic development and the dynamic nature of coastal environments into consideration to make these areas more resilient to climate change.
Published Report shows tectonics to be main driver of hillslope 'connectivity'
(via sciencedaily.com) A new large-scale analysis of hillslope connectivity at the continental scale was recently published. The study gives new understanding of mechanisms that determine how effectively hillslopes drive floods and landslides, as well as promote the presence of wetlands.
Published New nationwide strategy brings scientists, communities together to help reduce landslide risks
(via sciencedaily.com) Landslides are inevitable, but landslide disasters are not. With this in mind, the U.S. Geological Survey has released a new report that details the strategic actions necessary to equitably reduce the Nation's risk from landslide hazards.
Published Ancient landslide destroyed area size of Cincinnati
(via sciencedaily.com) University of Cincinnati geologists reconstructed a massive landslide in Nevada that wiped out an area the size of a small city more than 5 million years ago. Researchers pieced together details of the Blue Diamond landslide, a natural disaster that sent rocks and boulders tumbling more than 6 miles across what is now a desert outside Las Vegas. The landslide in Red Rock Canyon National Conservation Area had such mass and force that it propelled fragmented rock 2 miles uphill, cresting the enormous Blue Diamond Hill, and flattened an area larger than downtown Cincinnati. Rubble from the landslide stretches over an area of more than 7 square miles.
Published We need to change how we think about soil
(via sciencedaily.com) With record temperatures this summer along with dry conditions, ongoing concerns about food security, wildlife habitats and biodiversity, having a healthy soil system is more vital and challenging than ever before. But what does the term 'soil health' mean and how should we measure it? New research says that how we think about, measure and study soil must be changed to give a better understanding of how to manage this resource effectively, with academics proposing an entirely new approach for assessing soil health.
Published How charred detritus dispersed from Goleta Beach in wake of 2018 Montecito, California, debris flow
(via sciencedaily.com) The catastrophic debris flow that affected Montecito, Calif., in early January, 2018 was the result of a rare confluence of severe events. The Thomas Fire had been raging for weeks in Ventura and Santa Barbara counties, and an unusually strong winter storm dumped half an inch of rain in five minutes on the newly-charred hills above the suburban enclave. With the tough vegetation that holds the hillsides in place burned off by the fire, tons of water, silt, burnt plant matter and rocks roared down the slopes and engulfed the community below, causing massive damage and the death of 23 residents.