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Categories: Mathematics: Statistics, Physics: Acoustics and Ultrasound

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Researchers have modeled COVID-19 completion versus cessation in clinical trials using machine learning algorithms and ensemble learning.

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A major challenge in cancer therapy is the adaptive response of cancer cells to targeted therapies. Although this adaptive response is theoretically reversible, such a reversal is hampered by numerous molecular mechanisms that allow the cancer cells to adapt to the treatment. A team has used information theory, in order to objectify in vivo the molecular regulations at play in the mechanisms of the adaptive response and their modulation by a therapeutic combination.

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Engineers made a pneumatic RAM chip using microfluidic valves instead of electronic transistors. The valves remain sealed against a pressure differential even when disconnected from an air supply line, creating trapped pressure differentials that function as memories and maintain the states of a robot's actuators. Dense arrays of these valves can perform advanced operations and reduce the expensive, bulky, and power-consuming electronic hardware typically used to control pneumatic robots.

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Researchers have found that the magnetic field of the MRI scanner decreased the BBB opening volume by 3.3-fold to 11.7-fold, depending on the strength of the magnetic field, in a mouse model.

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Scientists have used a compound made from a starch derivative and baking soda to help convert mechanical to electrical energy. The approach is cost-effective and biocompatible, and can help charge low-energy electronics like calculators and watches.

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It may only be a matter of time until the growing problem of 'deep fakes' converges with geographical information science (GIS). A research team are doing what they can to get ahead of the problem.

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A team has developed a new brain stimulation technique using focused ultrasound that is able to turn specific types of neurons in the brain on and off and precisely control motor activity without surgical device implantation.

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Computational tools are indispensable in almost all scientific disciplines. Especially in cases where large amounts of research data are generated and need to be quickly processed, reliable, carefully developed software is crucial for analyzing and correctly interpreting such data. Nevertheless, scientific software can have quality quality deficiencies. To evaluate software quality in an automated way, computer scientists have designed the SoftWipe tool.

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Researchers have developed a new software tool to detect, evaluate and quantify off-target editing activity, including adverse translocation events that can cause cancer. The software is based on input taken from a standard measurement assay, involving multiplexed PCR amplification and Next-Generation Sequencing (NGS).

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High-end wireless and cellular networks rely on light for the distribution of signals. The selective processing of such signals requires long delays: too long to support on a chip using light alone. A research team brought together light and ultrasonic waves to realize ultra-narrow filters of microwave signals, in silicon integrated circuits. The concept allows large freedom for filters design.

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Researchers report that they have built what they say is the world's smallest single-chip system, consuming a total volume of less than 0.1 mm3. The system is as small as a dust mite and visible only under a microscope. In order to achieve this, the team used ultrasound to both power and communicate with the device wirelessly.

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The latest generation of personal alcohol breath testing devices pair with smartphones. While some of these devices were found to be relatively accurate, others may mislead users into thinking that they are fit to drive, according to a new study.

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Like conductors of a spooky symphony, researchers have 'entangled' two small mechanical drums and precisely measured their linked quantum properties. Entangled pairs like this might someday perform computations and transmit data in large-scale quantum networks.

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How can a highly effective drug be transported to the precise location in the body where it is needed? Chemists now present a solution using a molecular cage that opens through ultrasonification.

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New research demonstrates that noninvasive neuromodulation via low-intensity ultrasound can have cell-type selectivity in manipulating neurons.

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Inspired by a theoretical model of particles moving around on a chessboard, new robot swarm research shows that, as magnetic interactions increase, dispersed 'dumb robots' can abruptly gather in large, compact clusters to accomplish complex tasks. Researchers report that these 'BOBbots' (behaving, organizing, buzzing bots) are also capable of collectively clearing debris that is too heavy for one alone to move, thanks to a robust algorithm.

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Mathematicians and engineers have teamed up to show how ultrasound waves can organize carbon particles in water into a sort of pattern that never repeats. The results, they say, could result in materials called 'quasicrystals' with custom magnetic or electrical properties.

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The "three-body problem," the term coined for predicting the motion of three gravitating bodies in space, is essential for understanding a variety of astrophysical processes as well as a large class of mechanical problems, and has occupied some of the world's best physicists, astronomers and mathematicians for over three centuries. Their attempts have led to the discovery of several important fields of science; yet its solution remained a mystery.

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A reproducibility crisis is ongoing in scientific research, where many studies may be difficult or impossible to replicate and thereby validate, especially when the study involves a very large sample size. Now researchers have developed a statistical tool that can accurately estimate the replicability of a study, thus eliminating the need to duplicate the work and effectively mitigating the reproducibility crisis.

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A new brain imaging application uses ultrasound to predict intended movements before they happen.