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Categories: Chemistry: Organic Chemistry, Ecology: Research

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With a big assist from artificial intelligence and a heavy dose of human touch, a lab made a discovery that dramatically speeds up the time-consuming chemical process of building molecules that will be tomorrow's medicines, agrichemicals or materials.

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Protected marine areas are one of the essential tools for the conservation of natural resources affected by human impact -- mainly fishing --, but, are they enough to recover the functioning of these systems? A study now highlights the limitations of marine reserves in restoring food webs to their pristine state prior to the impact of intensive fishing.

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Hydrogen fuel could be a more viable alternative to traditional fossil fuels, according to University of Surrey researchers who have found that a type of metal-free catalysts could contribute to the development of cost-effective and sustainable hydrogen production technologies.

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The infamous spike proteins on the surface of SARS-CoV-2 help it bind to and enter human cells. Because of their important role in spreading infection, these spike proteins are one of the main targets for COVID-19 vaccines and treatments. But those remedies gradually lose effectiveness when certain segments of the spike proteins mutate. Now, researchers report that they have discovered small molecules that successfully target other segments that mutate less.

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A synthetic biosensor that mimics properties found in cell membranes and provides an electronic readout of activity could lead to a better understanding of cell biology, development of new drugs, and the creation of sensory organs on a chip capable of detecting chemicals, similar to how noses and tongues work.

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New research shows that degraded savanna ecosystems can reap lasting benefits from a single seeding of native understory plants. Once a diverse understory of savanna plants became established, its long-term persistence was relatively unaffected by environmental factors -- with one exception. Higher temperatures during the height of the growing season were associated with poorer long-term survival among some species, indicating one threat posed by a warming climate.

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A new examination of ancient and current species of reptiles conducted by paleobiologists reveals the serious impact of the disappearance of even a few species of reptiles in some island areas. The study has startling conclusions about how, on smaller islands in the Caribbean where human impact was greatest, extinctions have led to the loss of up to two-thirds of the supports for the ecosystem that native reptile species once provided there.

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Researchers discovered a new species of frog in Africa that has an unusual trait: it's completely silent. The Ukaguru spiny-throated reed frog does not croak, sing or ribbit. Found in Tanzania's Ukaguru Mountains for which it is named, Hyperolius ukaguruensis is among the few frogs around the world that do not vocalize to other frogs.

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Researchers have used single carbon atom doping to form four chemical bonds in one step. Gamma-lactams (cyclic molecules that are common in antibiotics) were easily synthetically accessible from alpha, beta-unsaturated amides (an important molecule in cancer progression). The team chemically modified an anti-seizure medication in 96% yield, highlighting the work's utility to otherwise synthetically complex aspects of pharmaceutical development. The results of this work could become foundational to drug discovery and development.

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Most cancer diagnostic techniques rely on uncomfortable and invasive procedures, such as biopsies, endoscopies or mammograms. Blood samples could be a less unpleasant option, though only a few forms of the disease can currently be diagnosed this way. But now, researchers have developed an easy-to-use method that can detect small amounts of cancer-related molecules in exosomes in plasma and effectively distinguish between malignant and benign samples.

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New research suggests nitrogen released by gas-powered machines causes dry soil to let go of carbon and release it back into the atmosphere, where it can contribute to climate change.

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Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like gene regulation has been greatly enhanced by the development of a process termed PETEOS -- short for peptidyl-tRNA enrichment using organic extraction and silica adsorption. This method allows for the large-scale harvesting, processing, and identification of pep-tRNA polypeptide moieties.

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In a new study, a research team discovered evidence that browsing by white-tailed deer had relatively little long-term impact on two tree species in a northern forest.

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A research team has developed a novel chemical tool to reveal how bacteria adapt to the host environment and control host cells. This tool can be used to investigate bacterial interactions with the host in real-time during an infection, which cannot be easily achieved by other methods.

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A new study has for the first time predicted which invasive species could pose a future threat to the UK's ecologically unique Overseas Territories.

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A new species of microalgae was found in water from a home aquarium. While analyzing DNA samples taken from the algae, researchers discovered Medakamo hakoo, whose DNA sequence didn't match any on record. This new species is the smallest known freshwater green algae, with inherent qualities which enable it to be cultured stably at high density, meaning it could be effectively used to produce useful products for food and industry.

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The speed of environmental change is very challenging for wild organisms. When exposed to a new environment individual plants and animals can potentially adjust their biology to better cope with new pressures they are exposed to -- this is known as phenotypic plasticity. New research shows that early plasticity can influence the ability to subsequently evolve genetic adaptations to conquer new habitats.

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Evolution has occurred more rapidly than previously thought in the Chesapeake Bay wetlands, which may decrease the chance that coastal marshes can withstand future sea level rise, researchers at the University of Notre Dame and collaborators demonstrated in a recent publication in Science.

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Nutrients from salmon carcasses can substantively alter the growth and reproduction of plant species in the surrounding habitat, and even cause some flowers to grow bigger and more plentiful, researchers have found.

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Rapid economic growth has pushed rare species of big carnivores to the brink of extinction, but ecologists have suggested our appetite to once again live alongside big cats is increasing.