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Categories: Biology: Developmental, Geoscience: Earthquakes

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The behavioral disorders observed in autism are associated with a multitude of genetic alterations. Scientists have now found another molecular cause for this condition. The transcription factor MYT1L normally protects the molecular identity of nerve cells. If it is genetically switched off in human nerve cells or in mice, the functional changes and symptoms typical of autism occur. A drug that blocks sodium channels in the cell membrane can reverse the consequences of MYT1L failure and alleviate the functional and behavioral abnormalities in mice.

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Scientists have created a new technology to assemble matter in 3D. Their concept uses multiple acoustic holograms to generate pressure fields with which solid particles, gel beads and even biological cells can be printed. These results pave the way for novel 3D cell culture techniques with applications in biomedical engineering.

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Bee researchers have identified a new gene in honeybees, which is responsible for the dimorphic eye differentiation between males and females of the species. The researchers have now presented this gene and the evolutionary genetic conclusions they have drawn from it.

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In a new study, researchers discovered an unknown mechanism of how cells 'remember' their identity when they divide -- the cells' so-called epigenetic memory.

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Computer software can predict what happens to complex gene networks when individual genes are missing or dialed up more than usual. Mapping the roles of single genes in these networks is key to understanding healthy development and finding ways to regrow damaged cells and tissues. Understanding genetic errors could provide insight into birth defects, miscarriage or even cancer.

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Cornell University researchers have unearthed precise, microscopic clues to where magma is stored, offering a way to better assess the risk of volcanic eruptions.

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Scientists have discovered a new layer of partly molten rock under the Earth's crust that might help settle a long-standing debate about how tectonic plates move. The molten layer is located about 100 miles from the surface and is part of the asthenosphere, which is important for plate tectonics because it forms a relatively soft boundary that lets tectonic plates move through the mantle. The researchers found, however that the melt does not appear to notably influence the flow of mantle rocks. Instead, they say, the discovery confirms that the convection of heat and rock in the mantle are the prevailing influence on the motion of the plates.

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Researchers show that brain organoids -- clumps of lab-grown neurons -- can integrate with rat brains and respond to visual stimulation like flashing lights.

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A new biomaterial that can be injected intravenously, reduces inflammation in tissue and promotes cell and tissue repair. The biomaterial was tested and proven effective in treating tissue damage caused by heart attacks in both rodent and large animal models. Researchers also provided proof of concept in a rodent model that the biomaterial could be beneficial to patients with traumatic brain injury and pulmonary arterial hypertension.

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A new species of microalgae was found in water from a home aquarium. While analyzing DNA samples taken from the algae, researchers discovered Medakamo hakoo, whose DNA sequence didn't match any on record. This new species is the smallest known freshwater green algae, with inherent qualities which enable it to be cultured stably at high density, meaning it could be effectively used to produce useful products for food and industry.

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A 'back-projection' technique reveals new details of the volcanic eruption in Tonga that literally shook the world.

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Scientists have created an AI system capable of generating artificial enzymes from scratch. In laboratory tests, some of these enzymes worked as well as those found in nature, even when their artificially generated amino acid sequences diverged significantly from any known natural protein.

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In a new study, researchers have managed to curb skin cancer. The study was conducted on artificial human skin.

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Scientists used the auxin-inducible degron 2 system on CTCF, bringing the novel approach to bear on a fundamental protein.

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Researchers uncover for the first time the mechanism that likely explains how embryos form either a larva or a miniature version of the adult.

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The transport of molecules along the cell's skeleton plays a role in cancer metastasis, researchers show.

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A protein that prepares DNA for replication also prevents the replication process from running out of control, according to a new study. The work solves a mystery that has long puzzled biologists.

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Under cold conditions, not only the mother plant but also the father plant can pass on its chloroplasts to the offspring.

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Scientists succeed in boosting the efficiency of CRISPR/Cas9 and related methods and modifying initially inaccessible DNA sequences. They fine-tuned these tools to enable effective genetic screening for modelling specific gene mutations.

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Immunogeneticists have discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including a life-threatening fungal pneumonia.