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Categories: Biology: Developmental, Geoscience: Landslides

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In a new study, researchers discovered an unknown mechanism of how cells 'remember' their identity when they divide -- the cells' so-called epigenetic memory.

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Computer software can predict what happens to complex gene networks when individual genes are missing or dialed up more than usual. Mapping the roles of single genes in these networks is key to understanding healthy development and finding ways to regrow damaged cells and tissues. Understanding genetic errors could provide insight into birth defects, miscarriage or even cancer.

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Researchers show that brain organoids -- clumps of lab-grown neurons -- can integrate with rat brains and respond to visual stimulation like flashing lights.

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A new biomaterial that can be injected intravenously, reduces inflammation in tissue and promotes cell and tissue repair. The biomaterial was tested and proven effective in treating tissue damage caused by heart attacks in both rodent and large animal models. Researchers also provided proof of concept in a rodent model that the biomaterial could be beneficial to patients with traumatic brain injury and pulmonary arterial hypertension.

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A new species of microalgae was found in water from a home aquarium. While analyzing DNA samples taken from the algae, researchers discovered Medakamo hakoo, whose DNA sequence didn't match any on record. This new species is the smallest known freshwater green algae, with inherent qualities which enable it to be cultured stably at high density, meaning it could be effectively used to produce useful products for food and industry.

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Scientists have created an AI system capable of generating artificial enzymes from scratch. In laboratory tests, some of these enzymes worked as well as those found in nature, even when their artificially generated amino acid sequences diverged significantly from any known natural protein.

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In a new study, researchers have managed to curb skin cancer. The study was conducted on artificial human skin.

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Scientists used the auxin-inducible degron 2 system on CTCF, bringing the novel approach to bear on a fundamental protein.

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Researchers uncover for the first time the mechanism that likely explains how embryos form either a larva or a miniature version of the adult.

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The transport of molecules along the cell's skeleton plays a role in cancer metastasis, researchers show.

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A protein that prepares DNA for replication also prevents the replication process from running out of control, according to a new study. The work solves a mystery that has long puzzled biologists.

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Under cold conditions, not only the mother plant but also the father plant can pass on its chloroplasts to the offspring.

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Scientists succeed in boosting the efficiency of CRISPR/Cas9 and related methods and modifying initially inaccessible DNA sequences. They fine-tuned these tools to enable effective genetic screening for modelling specific gene mutations.

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Immunogeneticists have discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including a life-threatening fungal pneumonia.

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The red junglefowl -- the wild ancestor of the chicken -- is losing its genetic diversity by interbreeding with domesticated birds, according to a new study.

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Las Vegas, with its rapid urbanization and desert landscape, is highly vulnerable to flooding. For this reason, flood managers have built an extensive system of drainage ditches and detention basins to protect the public. Now, a new study shows how intentional engineering and urban development are interacting with climate change to alter the timing and intensity of flood risk.

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Old Yellow Enzymes (OYEs) were discovered in the 1930s and have been the subject of much research ever since. This is because these biocatalysts -- coloured yellow by an auxiliary molecule -- are capable of performing reactions that are very valuable for the chemical industry, such as producing drug precursors or fragrances. Even though OYEs are found in many organisms, their natural role for these organisms has hardly been understood so far -- possibly because the research focus has been on their biotechnological application. Researchers have now shown that an OYE of the unicellular green alga Chlamydomonas reinhardtii is vital for this plant microorganism to protect itself from photooxidative stress.

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A new modelling study shows that the Seychelles and other islands in the western Indian Ocean are not responsible for most of the plastic waste that accumulates on their beaches. Indonesia, India, and Sri Lanka were found to be the main sources of land-based plastic debris. The Seychelles also accumulate significant amounts of plastic debris of marine origin from fisheries and shipping lanes. • The results highlight the urgent need for a legally-binding Global Plastics Treaty and greater enforcement of regional policies to reduce plastic waste.

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Heliozoan axopodia are important for their motility. However, the underlying mechanism of their axopodial contraction has remained ambiguous. Recently, researchers have reported that microtubules are simultaneously cleaved at multiple sites, allowing the radiating axopodia in a heliozoan, Raphidocystis contractilis, to disappear almost instantly. They have now identified the gene set and proteins involved in this microtubule disruption. This research can help develop a method to detect water pollution and evaluate the efficacy of new anticancer drugs.

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Many genetic diseases are caused by diverse mutations spread across an entire gene, and designing genome editing approaches for each patient's mutation would be impractical and costly.