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Categories: Biology: Developmental

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Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Viral defense protein speeds up female stem cell production      (via sciencedaily.com)     Original source 

A viral defense mechanism can be used to accelerate the creation of female stem cell lines in mice. The findings can boost efforts in medical research, drug testing, and regenerative therapies, particularly for women and individuals with two X chromosomes.

Biology: Biochemistry Biology: Cell Biology Biology: Developmental Biology: General Biology: Microbiology Biology: Molecular
Published

Do smells prime our gut to fight off infection?      (via sciencedaily.com)     Original source 

In nematodes and humans, mitochondrial stress in the nervous system initiates a whole-body response that is most pronounced in the gut. A recent study showed that in nematodes, the odor of a pathogen triggers the nervous system to broadcast this response to the rest of the organism, prepping mitochondria in intestinal cells to fight a bacterial infection. Humans, too, may be able to sense pathogenic odors that prepare the gut for an infection.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Mathematics: Modeling
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Cracking the code of life: new AI model learns DNA's hidden language      (via sciencedaily.com)     Original source 

With GROVER, a new large language model trained on human DNA, researchers could now attempt to decode the complex information hidden in our genome. GROVER treats human DNA as a text, learning its rules and context to draw functional information about the DNA sequences.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Microbiology
Published

Allergy cells' hidden secret      (via sciencedaily.com)     Original source 

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy symptoms such as tissue swelling and inflammation. Now, researchers have discovered a hidden talent of mast cells: they can capture and use another type of immune cell called neutrophils. This surprising discovery sheds new light on how our immune system works, particularly during allergic reactions.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Coinfecting viruses impede each other's ability to enter cells      (via sciencedaily.com)     Original source 

The process by which phages -- viruses that infect and replicate within bacteria -- enter cells has been studied for over 50 years. In a new study, researchers have used cutting-edge techniques to look at this process at the level of a single cell.

Anthropology: Early Humans Biology: Biochemistry Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Environmental: General Geoscience: Environmental Issues
Published

Genetic signatures of domestication identified in pigs, chickens      (via sciencedaily.com)     Original source 

Wild boars and red junglefowl gave rise to common pigs and chickens. These animals' genes evolved to express themselves differently, leading to signatures of domestication -- such as weaker bones and better viral resistance -- in pigs and chickens, according to a research team.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Talking about regeneration      (via sciencedaily.com)     Original source 

Researchers transferred genes from simple organisms capable of regenerating their bodies into common fruit flies, more complex animals that cannot. They found the transferred gene suppressed an age-related intestinal issue in the flies. Their results suggest studying genes specific to animals with high regenerative capability may uncover new mechanisms for rejuvenating stem cell function and extending the healthy lifespan of unrelated organisms.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

Unraveling a key junction underlying muscle contraction      (via sciencedaily.com)     Original source 

Using powerful new visualization technologies, researchers have captured the first 3-D images of the structure of a key muscle receptor, providing new insights on how muscles develop across the animal kingdom and setting the stage for possible future treatments for muscular disorders.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

Precise genetics: New CRISPR method enables efficient DNA modification      (via sciencedaily.com)     Original source 

A research group has developed a new method that further improves the existing CRISPR/Cas technologies: it allows a more precise and seamless introduction of tags into proteins at the gene level. This technology could significantly improve research on proteins in living organisms and opens up new possibilities for medical research.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Environmental: General Environmental: Water Geoscience: Environmental Issues Offbeat: Earth and Climate Offbeat: General Offbeat: Plants and Animals
Published

How researchers turn bacteria into cellulose-producing mini-factories      (via sciencedaily.com)     Original source 

Researchers have modified certain bacteria with UV light so that they produce more cellulose. The basis for this is a new approach with which the researchers generate thousands of bacterial variants and select those that have developed into the most productive.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Researchers decipher new molecular mechanisms related to biological tissue regeneration      (via sciencedaily.com)     Original source 

A study opens new perspectives to better understand how the molecular mechanisms involved in regenerative medicine work. The study focuses on tumor necrosis factor- (TNF- ) and its receptors TNFR, molecules of key interest in biomedicine due to their involvement in multiple diseases such as obesity related to type 2 diabetes mellitus, inflammatory bowel disease and several types of cancer.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Molecular Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals
Published

Lampreys possess a 'jaw-dropping' evolutionary origin      (via sciencedaily.com)     Original source 

Lampreys are one of only two living jawless vertebrates Jaws are formed by a key stem cell population called the neural crest New research reveals the gene regulatory changes that may explain morphological differences between jawed and jawless vertebrates.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics
Published

Researchers are closing in on a mouse model for late-onset Alzheimer's      (via sciencedaily.com)     Original source 

Researchers are working to create the first strain of mice that's genetically susceptible to late-onset Alzheimer's, with potentially transformative implications for dementia research.

Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular
Published

Research sheds light on the role of PTPRK in tissue repair and cancer      (via sciencedaily.com)     Original source 

New research has advanced our knowledge of multiple roles for PTPRK, a receptor tyrosine phosphatase linked to the regulation of cell-cell adhesion, growth factor signalling and tumor suppression. Through a characterization of the function of PTPRK in human cell lines and mice, the team distinguished catalytic and non-catalytic functions of PTPRK. The findings extend what is known about the signalling mechanisms involving PTPRK as a phosphatase and its role in colorectal health but also shed new light on the extent of its function via non-catalytic signalling mechanisms.

Biology: Biotechnology Biology: Developmental Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Dual action antibiotic could make bacterial resistance nearly impossible      (via sciencedaily.com)     Original source 

New drug that disrupts two cellular targets would make it much harder for bacteria to evolve resistance.

Biology: Developmental Biology: Genetics Biology: Molecular Offbeat: General Offbeat: Plants and Animals
Published

Fruit fly post-mating behavior controlled by male-derived peptide via command neurons, study finds      (via sciencedaily.com)     Original source 

Scientists have succeeded in pinpointing the neurons within a female fruit fly's brain that respond to signals from the male during mating.

Biology: Biotechnology Biology: Developmental Biology: Genetics Offbeat: General Offbeat: Plants and Animals
Published

Controlling mosquito populations through genetic breeding      (via sciencedaily.com)     Original source 

Researchers have found a new way to identify genetic targets useful for control of mosquito populations, potentially offering an alternative to insecticides. Their study focused on the genetic basis of species incompatibility. They crossed Ae. aegypti, a major global arboviral disease vector, and its sibling species, Ae. mascarensis, from the Indian Ocean. When offspring is crossed back with one parent, about 10 percent of the progeny becomes intersex and is unable to reproduce.

Biology: Biotechnology Biology: Developmental Biology: Genetics Biology: Molecular
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Transient structure in fly leg holds clue to insect shape formation      (via sciencedaily.com)     Original source 

A little leg may reveal something big about how closely related insect species can drastically differ in body shape, according to a new study. The team imaged live cells of fruit flies in the last stages of development over several days and found a new structure that appears to help guide a section of the leg into its final shape.