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Categories: Biology: Biochemistry, Space: Astrophysics

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New research has revealed a previously unknown process through which pathogens are able to defeat a cell's defense mechanisms with physical force. The discovery represents a potential game-changer in the fight against intracellular pathogens, which cause infectious diseases such as tuberculosis, malaria and chlamydia.

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Upon infection or immunization, all jawed vertebrate species generate proteins called antibodies that bind and neutralize pathogens. Strong and long-lasting antibody responses in warm-blooded species such as mammals are produced in secondary lymphoid microstructures (SLMs) among which germinal centers (GCs) are the centerpiece. Despite the apparent absence of GCs or similar SLMs in cold-blooded vertebrates (e.g., fish), these species can mount significant antibody responses that can persist for several months. Thus, for decades, the outstanding question has remained as to how and where antibody responses are generated in species that lack GCs or analogous SLM structures.

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Astronomers studying images from the James Webb Space Telescope have identified an object as a 'dusty star-forming galaxy' from nearly 1 billion years after the Big Bang. They have also discovered more than a dozen additional candidates, suggesting these galaxies might be three to 10 times as common as expected. If that conclusion is confirmed, it suggests the early universe was much dustier than previously thought.

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Some nonnative plants cultivated in public gardens or arboretums are escaping to become invasive in wild forests.

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Children must be taught more about the importance of plants if education about climate change and sustainability is to be effective, experts have warned.

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A simple-to-apply, needle-free vaccine patch is being developed to protect people from the potentially deadly mosquito-borne Zika virus.

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Micrometeorites originating from icy celestial bodies in the outer Solar System may be responsible for transporting nitrogen to the near-Earth region in the early days of our solar system.

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Pentoses are essential carbohydrates in the metabolism of modern lifeforms, but their availability on early Earth is unclear since these molecules are unstable. Now, researchers reveal a chemical pathway compatible with early Earth conditions, by which C6 aldonates could have acted as a source of pentoses without the need for enzymes. Their findings provide clues about primitive biochemistry and bring us closer to understanding life's origin.

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The universe is expanding. How fast it does so is described by the so-called Hubble-Lemaitre constant. But there is a dispute about how big this constant actually is: Different measurement methods provide contradictory values. This so-called 'Hubble tension' poses a puzzle for cosmologists. Researchers are now proposing a new solution: Using an alternative theory of gravity, the discrepancy in the measured values can be easily explained -- the Hubble tension disappears.

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Maternal-fetal listeriosis is a severe disease that can lead to miscarriage, premature birth or serious neonatal infection. But what are the long-term consequences of neonatal listeriosis on the health of surviving infants? A team of scientists and physicians monitored the development of children infected with the bacterium Listeria monocytogenes up to the age of 5, and compared their development with that of uninfected gestational age-matched children. The study showed that the long-term outcomes of neonatal listeriosis were mainly due to prematurity.

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For the first time, scientists have begun to figure out why the disfiguring skin lesions caused by cutaneous leishmaniasis don't hurt.

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During a two-year survey of soft corals in the Florida Keys,  scientists identified three species of octocorals that have survived heat waves. While the coral animal itself may be heat tolerant, scientists concluded that the symbiotic algae inside the coral serve as a protector of sorts.

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Scientists sequenced the genome of the East Asian pitcher plant, Nepenthes gracilis, a species of carnivorous plant related to Venus flytraps, as well as sundews, beets and spinach.

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The discovery of a planet that is far too massive for its sun is calling into question what was previously understood about the formation of planets and their solar systems.

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In sea fireflies' underwater ballet, the males sway together in perfect, illuminated synchronization, basking in the glow of their secreted iridescent mucus.

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As California, the U.S. and the world work to make good on commitments to conserve 30% of oceans and lands by 2030, all strategies are on the table -- and under the microscope. When it comes to the ocean, one valuable tool is marine protected areas (MPAs), regions that are defined, designated and managed for long-term conservation. Among other benefits, MPAs protect habitats and promote species diversity. They also hold value for communities and industries.  

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Astronomers have provided the first observation of water and other molecules in the highly irradiated inner, rocky-planet-forming regions of a disk in one of the most extreme environments in our galaxy. These results suggest that the conditions for terrestrial planet formation can occur in a possible broader range of environments than previously thought. 

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Maize is one of the world's most widely grown crops. It is used for both human and animal foods and holds great cultural significance, especially for indigenous peoples in the Americas. Yet despite its importance, the origins of the grain have been hotly debated for more than a century. Now new research shows that all modern maize descends from a hybrid created just over 5000 years ago in central Mexico, thousands of years after the plant was first domesticated.

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The increased legalization of cannabis over the past several years can potentially increase its co-use with alcohol. Concerningly, very few studies have looked at the effects of these two drugs when used in combination. In a series of new studies, researchers at used rats to understand how brain structure and behavior can change when cannabis and alcohol are taken together.

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There's a species of ant that is so rare, only a handful of records exist from across the entire eastern United States. North Carolina State University researcher Michelle Kirchner not only found these ants in the Triangle region of North Carolina, she is the first to document an entire colony for scientists, taxonomists and ant-thusiasts everywhere. It is the first time males of the species have been collected or photographed.