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Categories: Biology: Biotechnology, Physics: General

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Researchers have developed a metasurface that enables strong coupling effects between light and transition metal dichalcogenides (TMDCs).

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Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn. Scientists are studying the conformational landscapes of biomolecules and how they modulate cell function. When biomolecules receive certain inputs, it can cause the atoms to rearrange and the biomolecule to change shape. This change in shape affects their function in cells, so understanding conformational dynamics is critical for drug development.

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Researchers have deciphered a biochemical mechanism that ensures that newly formed proteins are processed correctly when they leave the cell's own protein factories. This solves a decade-old puzzle in protein sorting.

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An obscure aquatic plant has helped to explain how plants avoid cracking up under the stresses and strains of growth.

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The cosmos is a unique laboratory for testing the laws of physics, in particular those of Euler and Einstein. Euler described the movements of celestial objects, while Einstein described the way in which celestial objects distort the Universe. Since the discovery of dark matter and the acceleration of the Universe's expansion, the validity of their equations has been put to the test: are they capable of explaining these mysterious phenomena? A team has developed the first method to find out. It considers a never-before-used measure: time distortion.

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The herpes simplex virus-1 can sometimes cause a dangerous brain infection. Combining an anti-inflammatory and an antiviral could help in these cases, report scientists.

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Engineers designed a technology to probe connections between the brain and the digestive tract. Using fibers embedded with a variety of sensors, as well as optogenetic stimulation, the researchers could control neural circuits connecting the gut and the brain, in mice.

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For the first time, researchers have developed a genome-scale way to map the regulatory role of transcription factors, proteins that play a key role in gene expression and determining a plant's physiological traits. Their work reveals unprecedented insights into gene regulatory networks and identifies a new library of DNA parts that can be used to optimize plants for bioenergy and agriculture.

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Scientists have built a new, comprehensive AutoML platform designed for biologists with little to no ML experience. New automated machine learning platform enables easy, all-in-one analysis, design, and interpretation of biological sequences with minimal coding. Their platform, called BioAutoMATED, can use sequences of nucleic acids, peptides, or glycans as input data, and its performance is comparable to other AutoML platforms while requiring minimal user input.

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DNA can mimic protein functions by folding into elaborate, three-dimensional structures, according to a new study.

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Quantum researchers twist double bilayers of an antiferromagnet to demonstrate tunable moiré magnetism.

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Scientists have demonstrated a capability long sought by physicists: transmitting extremely precise time signals through the air between far-flung locations at powers that are compatible with future space-based missions. The results could enable time transfer from the ground to satellites in geosynchronous orbit with femtosecond precision -- 10,000 times better than the existing state-of-the-art satellite approaches. It also would allow for successful synchronization using the bare minimum timing signal strength, which would make the system highly robust in the face of atmospheric disturbances.

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Researchers have outlined the structure and function of a protein complex which is required to repair damaged DNA and protect against cancer.

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Scientists have uncovered a new quality control system that removes damaged cells from early developing embryos.

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Researchers have used an unprecedented stem cell zoo to compare six different mammalian species and their developmental time.

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In the face of the biodiversity crisis, and alarming data showing a 69% decline in global animal populations since 1970, researchers are banking on a cool solution to help save species from extinction. Much like egg-freezing is used to preserve human fertility options for a later date, the cryo-freezing of genetic samples taken from animals may play an essential role in curbing species extinctions. A new study sheds light on the immense potential of living cell banks, also known as cryobanks, to contribute to global conservation priorities.

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Genome Architecture Mapping captures complex, multi-way interactions in the genome. This is different than the workhorse technique of 3D genomics, which sees mostly two-way contacts, finds a new study.

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Scientists discover shattered chromosomal fragments are tethered together during cell division before being rearranged; destroying the tether may help prevent cancerous mutations.

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A team or researchers reports the first Aging Fly Cell Atlas (AFCA), a detailed characterization of the aging process in 163 distinct cell types in the laboratory fruit fly. Their in-depth analysis revealed that different cell types in the body age differently, each cell type following a process involving cell type-specific patterns. AFCA provides a valuable resource for researchers in the fruit fly and aging communities as a reference to study aging and age-related diseases and to evaluate the success of anti-aging strategies.

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A study demonstrates that graphene-based materials can be used to efficiently convert high-frequency signals into visible light, and that this mechanism is ultrafast and tunable. These outcomes open the path to exciting applications in near-future information and communication technologies.