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Categories: Biology: Genetics
Published Researchers make breakthrough in understanding species abundance
(via sciencedaily.com) Original source The key finding was that temperature and genome size, not body size, had the greatest influence on the maximum population growth rate of the diatoms. Yet body size still mattered in colder latitudes, conserving Bermann's Rule.
Published Microscopy technique 'paves way' for improving understanding of cellular functions
(via sciencedaily.com) Original source Scientists have developed a new way of counting labelled proteins in living cells that could become a standard and valuable tool in the field of biomedical research.
Published Unlocking the secrets of salt stress tolerance in wild tomatoes
(via sciencedaily.com) Original source As our climate changes and soil salinity increases in many agricultural areas, finding crops that can thrive in these challenging conditions is crucial. Cultivated tomatoes, while delicious, often struggle in salty soils. Their wild cousins, however, have evolved to survive in diverse and often harsh environments. A recent study delved into the genetic treasure trove of wild tomatoes to uncover secrets of salt tolerance that could be used to develop resilient crop varieties.
Published Mix of factors prompts owl monkeys to leave their parents
(via sciencedaily.com) Original source There comes a point in the lives of young owl monkeys when they leave their parents and strike out on their own to find a mate. In a new study of a wild population of Azara's owl monkeys in northern Argentina, researchers reveal that a combination of social and ecological factors influences when these tree-dwelling monkeys peel away from their parents and siblings. According to their findings -- which were based on 25 years of genetic and demographic data for several generations of owl monkeys, covering more than 330 individuals -- none of the individuals, regardless of their sex, reproduced in the same group where they were born. In all cases, the researchers found, the animals either departed from their natal group or died before reproducing.
Published How ribosomes in our cells enable protein folding
(via sciencedaily.com) Original source Scientists discovered a role played by ribosomes during the folding of new proteins in cells.
Published Viral defense protein speeds up female stem cell production
(via sciencedaily.com) Original source A viral defense mechanism can be used to accelerate the creation of female stem cell lines in mice. The findings can boost efforts in medical research, drug testing, and regenerative therapies, particularly for women and individuals with two X chromosomes.
Published Discovering how plants make life-and-death decisions
(via sciencedaily.com) Original source Researchers have discovered two proteins that work in tandem to control an important response to cell stress.
Published Pesticide contamination is more than apple skin deep
(via sciencedaily.com) Original source Pesticides and herbicides are critical to ensuring food security worldwide, but these substances can present a safety risk to people who unwittingly ingest them. Protecting human health, therefore, demands sensitive analytical methods to identify even trace levels of potentially harmful substances. Now, researchers have developed a high-tech imaging method to detect pesticide contamination at low levels, and its application on fruits reveals that current food safety practices may be insufficient.
Published Researchers find gene which determines marsupial fur color
(via sciencedaily.com) Original source Fur is a defining characteristic of mammals, coming in a wide variety of colors and patterns -- thanks to a world-first study, we now know which genes make a marsupial's coat black or grey.
Published Horse miscarriages offer clues to causes of early human pregnancy loss
(via sciencedaily.com) Original source A study of horses -- which share many important similarities with humans in their chromosomes and pregnancies -- revealed that 42% of miscarriages and spontaneous abortions in the first two months of pregnancy were due to complications from an extra set of chromosomes, a condition called triploidy.
Published Study analyzes potato-pathogen 'arms race' after Irish famine
(via sciencedaily.com) Original source Researchers reveal more about the tit-for-tat evolutionary changes occurring in both potato plants and the pathogen that caused the 1840s Irish potato famine.
Published Cracking the code of life: new AI model learns DNA's hidden language
(via sciencedaily.com) Original source With GROVER, a new large language model trained on human DNA, researchers could now attempt to decode the complex information hidden in our genome. GROVER treats human DNA as a text, learning its rules and context to draw functional information about the DNA sequences.
Published Why virus causing cold sores does not spread to devastating brain infection
(via sciencedaily.com) Original source A previously unknown defence mechanism in the brain prevents herpesvirus from infecting the brain's nerve cells.
Published Discovery of a new population of macrophages promoting lung repair after viral infections
(via sciencedaily.com) Original source Researchers have discovered a new population of macrophages, important innate immune cells that populate the lungs after injury caused by respiratory viruses. These macrophages are instrumental in repairing the pulmonary alveoli. This groundbreaking discovery promises to revolutionize our understanding of the post-infectious immune response and opens the door to new regenerative therapies.
Published Coinfecting viruses impede each other's ability to enter cells
(via sciencedaily.com) Original source The process by which phages -- viruses that infect and replicate within bacteria -- enter cells has been studied for over 50 years. In a new study, researchers have used cutting-edge techniques to look at this process at the level of a single cell.
Published Circular RNAs: The new frontier in cancer research
(via sciencedaily.com) Original source Unravelling the complexities of circular RNAs (circRNAs) in cancer biology has positioned scientists on the cusp of revolutionary breakthroughs in the diagnosis and treatment of cancer. A new study predicts remarkable potential for circular RNAs to improve cancer treatment and patient outcomes within the next 5-10 years.
Published What gave the first molecules their stability?
(via sciencedaily.com) Original source The origins of life remain a major mystery. How were complex molecules able to form and remain intact for prolonged periods without disintegrating? A team has demonstrated a mechanism that could have enabled the first RNA molecules to stabilize in the primordial soup. When two RNA strands combine, their stability and lifespan increase significantly.
Published Genetic signatures of domestication identified in pigs, chickens
(via sciencedaily.com) Original source Wild boars and red junglefowl gave rise to common pigs and chickens. These animals' genes evolved to express themselves differently, leading to signatures of domestication -- such as weaker bones and better viral resistance -- in pigs and chickens, according to a research team.
Published When it comes to DNA replication, humans and baker's yeast are more alike than different
(via sciencedaily.com) Original source Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies. The findings visualize for the first time a molecular complex -- called CTF18-RFC in humans and Ctf18-RFC in yeast -- that loads a 'clamp' onto DNA to keep parts of the replication machinery from falling off the DNA strand.
Published Novel nanosensing technique for quality control of viral vectors in gene therapy
(via sciencedaily.com) Original source Researchers develop a nanosensing platform that can assess the quality of individual viral vector particles Viral vectors hold much potential for gene editing and gene therapy, but there is a pressing need to develop quality control methods to minimize potential side effects on patients. Addressing this, researchers from Japan developed a nanosensing-based approach that can differentiate between functional and faulty viral vectors at the single-particle level. This convenient and inexpensive technique will hopefully get us one step closer to advancing treatments for genetic disorders.