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Categories: Biology: Evolutionary, Chemistry: Biochemistry

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Researchers have developed a new type of microscope that stitches together video from 54 individual cameras and lenses. Whether recording high-speed, 3D, gigapixel movies of the behavior of dozens of freely swimming zebrafish or the grooming activity of fruit flies at near cellular-level detail across a very wide field of view, the device is opening new possibilities to researchers the world over.

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Researchers found they could separate blended cotton and polyester fabric using enzymes -- nature's tools for speeding chemical reactions. Ultimately, they hope their findings will lead to a more efficient way to recycle the fabric's component materials, thereby reducing textile waste.

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Researchers have devised a tiny, nano-sized sensor capable of detecting protein biomarkers in a sample at single-molecule precision. Fittingly coined as 'hook and bait,' a tiny protein binder fuses to a small hole created in the membrane of a cell -- known as a nanopore ­-- which allows ionic solution to flow through it. When the sensor recognizes a targeted molecule, the ionic flow changes. This change in flow serves as the signal from the sensor that the biomarker has been found.

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Cultivation and growth of grapevines have strongly influenced European civilizations, but where the grapevine comes from and how it has spread across the globe has been highly disputed so far. In an extensive genome project, researchers have determined its origin and evolution from the wild vine to today's cultivar by analyzing thousands of vine genomes collected along the Silk Road from China to Western Europe.

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Sunlight can be used to produce green hydrogen directly from water in photoelectrochemical (PEC) cells. So far, most systems based on this 'direct approach' have not been energetically competitive. However, the balance changes as soon as some of the hydrogen in such PEC cells is used in-situ for a catalytic hydrogenation reaction, resulting in the co-production of chemicals used in the chemical and pharmaceutical industries. The energy payback time of photoelectrochemical 'green' hydrogen production can be reduced dramatically, the study shows.

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How light interacts with matter has always fired the imagination. Now scientists for the first time have demonstrated the ability to manipulate single and double atoms exhibiting the properties of simulated light emission. This creates prospects for advances in photonic quantum computing and low-intensity medical imaging.

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Scientists show the commanding role of a specialized group of proteins in the nuclei of our cells, called mSWI/SNF (or BAF) complexes, both in activating T cells to attack cancer and triggering exhaustion. The discovery suggests that targeting certain of these complexes, either by gene-cutting technologies such as CRISPR or with targeted drugs, could reduce T cell exhaustion and give CAR T cells (and in general, all tumor-fighting T cells) the staying power to take on cancer.

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When lymphatic vessels fail, typically their ability to pump out the fluid is compromised. Researchers have now developed a new treatment using nanoparticles that can repair lymphatic vessel pumping. Traditionally, researchers in the field have tried to regrow lymphatic vessels, but repairing the pumping action is a unique approach.

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A research team develops transfer-tattoo-like cell-sheet delivery induced by interfacial cell migration.

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Researchers have developed biosensor technology that will allow you to operate devices, such as robots and machines, solely through thought control.

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Scientists developing new biomaterials often try to mimic the body's natural proteins, but a chemist shows that simpler polymers -- based on a handful of plastic building blocks -- also work well. Using AI, her team was able to design polymer mixtures that replicate simple protein functions within biological fluids. The random heteropolymers dissolve and stabilize proteins and can support cells' normal protein-making machinery. The technique could speed the design of materials for biomedical applications.

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A new way of describing the connections in real-world systems such as food webs or social networks could lead to better methods for predicting and controlling them.

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Ice surfaces have a thin layer of water below its melting temperature of 0 degrees Celsius. Such premelting phenomenon is important for skating and snowflake growth. Similarly, liquid often crystallizes into a thin layer of crystal on a flat substrate before reaching its freezing temperature, i.e. prefreezing. The thickness of the surface layer usually increases and diverges as approaching the phase transition (such as melting and freezing) temperature. Besides premelting and prefreezing, whether similar surface phenomenon exists as a precursor of a phase transition has rarely been explored. Scientists now propose that a polymorphic crystalline layer may form on a crystal surface before the crystal-crystal phase transition and names it pre-solid-solid transition.

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Researchers uncovered the role of the third intracellular loop in the G protein-coupled receptors' signaling mechanism, which could lead to a more targeted approach to drug discovery and a paradigm shift for new therapeutics.

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Intense fishing and over-exploitation have led to evolutionary changes in fish stocks like cod, reducing both their productivity and value on the market. These changes can be reversed by more sustainable and far-sighted fisheries management. A new study shows that reversal of evolutionary change would only slightly reduce the profit of fishing, but would help regain and conserve natural genetic diversity.

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Researchers have reported a novel method of harvesting water from naturally occurring sources such as fog and dew.

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In organic solar cells, carbon-based polymers convert light into charges that are passed to an acceptor. Scientists have now calculated how this happens by combining molecular dynamics simulations with quantum calculations and have provided theoretical insights to interpret experimental data.

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There's been a well-documented shift toward earlier springtime flowering in many plants as the world warms. The trend alarms biologists because it has the potential to disrupt carefully choreographed interactions between plants and the creatures -- butterflies, bees, birds, bats and others -- that pollinate them.

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Pushing the MINFLUX technique to higher spatial and temporal precision allows protein dynamics to be observed under physiological conditions.

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The western chimpanzees of Guinea are threatened by mining activities. Using a novel genetic approach, researchers have collected information on population size and community structure of the endangered species. These data provide an important baseline to assess the impact of mining.