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Categories: Biology: Evolutionary, Chemistry: Biochemistry
Published Transforming inexpensive quinolines into complex drug candidates
(via sciencedaily.com) Original source An innovative synthesis strategy opened up the way to 2D/3D fused frameworks using inexpensive quinolines as feedstock, report scientists. By leveraging a light-sensitive borate intermediate, the scientists could transform quinoline derivatives into a great variety of 2D/3D fused frameworks in a straightforward and cost-effective manner. Their findings are expected to enable the synthesis of highly customizable drug candidates.
Published Interaction with insects accelerates plant evolution
(via sciencedaily.com) Original source Researchers have discovered that plants benefit from a greater variety of interactions with pollinators and herbivores. Plants that are pollinated by insects and have to defend themselves against herbivores have evolved to be better adapted to different types of soil.
Published A railroad of cells
(via sciencedaily.com) Original source Looking under the microscope, a group of cells slowly moves forward in a line, like a train on the tracks. The cells navigate through complex environments. A new approach now shows how they do this and how they interact with each other.
Published Much of the Nord Stream gas remained in the sea
(via sciencedaily.com) Original source Much of the methane released into the southern Baltic Sea from the Nord Stream gas pipeline has remained in the water. This is shown by measurements taken by researchers from the University of Gothenburg.
Published New technology provides electrifying insights into how catalysts work at the atomic level
(via sciencedaily.com) Original source A team has invented a technique to study electrochemical processes at the atomic level with unprecedented resolution. They have already used it to discover a surprising phenomena in a popular catalyst material and plan to apply their technology to studying a wide variety of electrochemical systems including batteries, fuel cells, and solar fuel generators. The insights could lead to more efficient and durable devices.
Published Researchers create new class of materials called 'glassy gels'
(via sciencedaily.com) Original source Researchers have created a new class of materials called 'glassy gels' that are very hard and difficult to break despite containing more than 50% liquid. Coupled with the fact that glassy gels are simple to produce, the material holds promise for a variety of applications.
Published Mirror-image chemicals may revolutionize drug delivery
(via sciencedaily.com) Original source More than 130 years after cyclodextrins were first discovered and reported, a team of scientists has created chemical mirror images of these complex carbohydrates in the laboratory. This discovery may revolutionize how medications are delivered to patients.
Published Unveiling Telo-seq: A breakthrough in telomere research on aging and cancer
(via sciencedaily.com) Original source Telo-seq -- a new tool -- is bringing telomere science into its modern era. Scientists can finally explore questions about the role of telomeres in aging and cancer that were not accessible with previous methods. The findings will inspire novel telomere-targeting therapeutics for aging-related diseases.
Published Custom-made molecules designed to be invisible while absorbing near-infrared light
(via sciencedaily.com) Original source Researchers used theoretical calculations assessing electron orbital symmetry to synthesize new molecule designed to be both transparent and colorless while absorbing near-infrared light. This compound demonstrates the first systematic approach to producing such materials and have applications in advanced electronics. This compound also shows semiconducting properties.
Published Nile perch invasion triggered genetic bottlenecks in Lake Victoria's endemic cichlids
(via sciencedaily.com) Original source Newfound evidence reveals that the upsurge of the exotic Nile perch in Lake Victoria had long-lasting effects on the genetic diversity of various local cichlid species, report scientists. Through large-scale comparative genomic analyses, the researchers found concrete proof in the collective genome of multiple species that this artificially introduced perch decimated many local fish populations, causing a 'bottleneck effect.'
Published Previously uncharacterized parasite uncovered in fish worldwide
(via sciencedaily.com) Original source Using genome reconstruction, scientists unveiled a once 'invisible' fish parasite present in many marine fish world-wide that belongs to the apicomplexans, one of the most important groups of parasites at a clinical level. However, it had gone unnoticed in previous studies. The parasite is geographically and taxonomically widespread in fish species around the planet, with implications for commercial fishing and oceanic food webs.
Published Molecular sponge for the electronics of the future
(via sciencedaily.com) Original source An international research team has succeeded in developing a new type of material in the rather young research field of covalent organic frameworks. The new two-dimensional polymer is characterized by the fact that its properties can be controlled in a targeted and reversible manner. This has brought the researchers a step closer to the goal of realizing switchable quantum states.
Published Ancient polar sea reptile fossil is oldest ever found in Southern Hemisphere
(via sciencedaily.com) Original source An international team of scientists has identified the oldest fossil of a sea-going reptile from the Southern Hemisphere -- a nothosaur vertebra found on New Zealand's South Island. 246 million years ago, at the beginning of the Age of Dinosaurs, New Zealand was located on the southern polar coast of a vast super-ocean called Panthalassa. 'The nothosaur found in New Zealand is over 40 million years older than the previously oldest known sauropterygian fossils from the Southern Hemisphere.
Published Finding hidden genetic treasure: Study uncovers untapped diversity in historic wheat collection
(via sciencedaily.com) Original source A decade-long study has discovered huge genetic potential that is untapped in modern wheat varieties.
Published Breakthrough approach enables bidirectional BCI functionality
(via sciencedaily.com) Original source Brain-computer interfaces or BCIs hold immense potential for individuals with a wide range of neurological conditions, but the road to implementation is long and nuanced for both the invasive and noninvasive versions of the technology. Scientists have now successfully integrated a novel focused ultrasound stimulation to realize bidirectional BCI that both encodes and decodes brain waves using machine learning in a study with 25 human subjects. This work opens up a new avenue to significantly enhance not only the signal quality, but also, overall nonivasive BCI performance by stimulating targeted neural circuits.
Published Research into structures of ape hearts provide insight into human evolution
(via sciencedaily.com) Original source Researchers have discovered new insights into the human heart's structure, revealing its evolutionary history. This study enhances understanding of heart development and its implications for treating heart disease.
Published Some CRISPR screens may be missing cancer drug targets
(via sciencedaily.com) Original source CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily depend on to survive and grow. These genes, or 'cancer dependencies,' are often promising drug targets. But new research shows that many of these CRISPR screening experiments rely on components, called CRISPR/Cas9 guides, that do not perform equally well in cells from people of all ancestries, which can cause CRISPR screens to miss cancer dependencies.
Published When bacteria are buckling
(via sciencedaily.com) Original source Filamentous cyanobacteria buckle at a certain length when they encounter an obstacle. The results provide an important basis for the use of cyanobacteria in modern biotechnology.
Published Nano-immunotherapy developed to improve lung cancer treatment
(via sciencedaily.com) Original source Researchers have developed a new nanomedicine therapy that delivers anticancer drugs to lung cancer cells and enhances the immune system's ability to fight cancer. The team showed promising results for the new therapy in cancer cells in the lab and in mouse lung tumor models, with potential applications for improving care and outcomes for patients with tumors that have failed to respond to traditional immunotherapy.
Published Strengthener for graphene
(via sciencedaily.com) Original source Layers of carbon atoms in a honeycomb array are a true supermaterial: their unusually high conductivity and favorable mechanical properties could further the development of bendable electronics, new batteries, and innovative composite materials for aeronautics and space flight. However, the development of elastic and tough films remains a challenge. A research team has now introduced a method to overcome this hurdle: they linked graphene nanolayers via 'extendable' bridging structures.