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Categories: Chemistry: Biochemistry, Environmental: Wildfires
Published Researchers develop RNA-targeting technology for precisely manipulating parts of human genes
(via sciencedaily.com) Original source Researchers have harnessed a bacterial immune defense system, known as CRISPR, to efficiently and precisely control the process of RNA splicing. The technology opens the door to new applications, including systematically interrogating the functions of parts of genes and correcting splicing deficiencies that underlie numerous diseases and disorders.
Published Fuel treatments reduce future wildfire severity
(via sciencedaily.com) Original source There is a common belief that prescribed burning, thinning trees, and clearing underbrush reduce risks of the severity of future fires. But is that true? A new project analyzing 40 studies where wildfire burned into different vegetation treatments, spanning 11 western states. Researchers found overwhelming evidence that in seasonally dry mixed conifer forests in the western U.S., reducing surface and ladder fuels and tree density through thinning, coupled with prescribed burning or pile burning, could reduce future wildfire severity by more than 60% relative to untreated areas.
Published Researchers engineer AI path to prevent power outages
(via sciencedaily.com) Original source Researchers developed an artificial intelligence (AI) model that could help electrical grids prevent power outages by automatically rerouting electricity in milliseconds. The approach is an early example of 'self-healing grid' technology, which uses AI to detect and repair problems such as outages autonomously and without human intervention when issues occur, such as storm-damaged power lines.
Published Prying open the AI black box
(via sciencedaily.com) Original source Meet SQUID, a new computational tool. Compared with other genomic AI models, SQUID is more consistent, reduces background noise, and can yield better predictions regarding critical mutations. The new system aims to bring scientists closer to their findings' true medical implications.
Published Controlling electronics with light: The magnetite breakthrough
(via sciencedaily.com) Original source Researchers have discovered that by shining different wavelengths (colors) of light on a material called magnetite, they can change its state, e.g. making it more or less conducive to electricity. The discovery could lead to new ways of designing new materials for electronics such as memory storage, sensors, and other devices that rely on fast and efficient material responses.
Published Membrane protein analogues could accelerate drug discovery
(via sciencedaily.com) Original source Researchers have created a deep learning pipeline for designing soluble analogues of key protein structures used in pharmaceutical development, sidestepping the prohibitive cost of extracting these proteins from cell membranes.
Published Lab-grown muscles reveal mysteries of rare muscle diseases
(via sciencedaily.com) Original source Biomedical engineers have grown muscles in a lab to better understand and test treatments for a group of extremely rare muscle disorders called dysferlinopathy or limb girdle muscular dystrophies 2B (LGMD2B). The research revealed the biological mechanisms underlying the disease and showed that a combination of existing treatments could alleviate its symptoms.
Published Scientists discover new behavior of membranes that could lead to unprecedented separations
(via sciencedaily.com) Original source Argonne scientists have used isoporous membranes -- membranes with pores of equal size and shape -- and recirculation to create separations at the nanoscale that overcome previous limitations.
Published Scientists devise algorithm to engineer improved enzymes
(via sciencedaily.com) Original source Scientists have prototyped a new method for 'rationally engineering' enzymes to deliver improved performance. They have devised an algorithm, which takes into account an enzyme's evolutionary history, to flag where mutations could be introduced with a high likelihood of delivering functional improvements. Their work could have significant, wide-ranging impacts across a suite of industries, from food production to human health.
Published Creation of a power-generating, gel electret-based device
(via sciencedaily.com) Original source A team of researchers has developed a gel electret capable of stably retaining a large electrostatic charge. The team then combined this gel with highly flexible electrodes to create a sensor capable of perceiving low-frequency vibrations (e.g., vibrations generated by human motion) and converting them into output voltage signals. This device may potentially be used as a wearable healthcare sensor.
Published Transforming inexpensive quinolines into complex drug candidates
(via sciencedaily.com) Original source An innovative synthesis strategy opened up the way to 2D/3D fused frameworks using inexpensive quinolines as feedstock, report scientists. By leveraging a light-sensitive borate intermediate, the scientists could transform quinoline derivatives into a great variety of 2D/3D fused frameworks in a straightforward and cost-effective manner. Their findings are expected to enable the synthesis of highly customizable drug candidates.
Published A railroad of cells
(via sciencedaily.com) Original source Looking under the microscope, a group of cells slowly moves forward in a line, like a train on the tracks. The cells navigate through complex environments. A new approach now shows how they do this and how they interact with each other.
Published Much of the Nord Stream gas remained in the sea
(via sciencedaily.com) Original source Much of the methane released into the southern Baltic Sea from the Nord Stream gas pipeline has remained in the water. This is shown by measurements taken by researchers from the University of Gothenburg.
Published New technology provides electrifying insights into how catalysts work at the atomic level
(via sciencedaily.com) Original source A team has invented a technique to study electrochemical processes at the atomic level with unprecedented resolution. They have already used it to discover a surprising phenomena in a popular catalyst material and plan to apply their technology to studying a wide variety of electrochemical systems including batteries, fuel cells, and solar fuel generators. The insights could lead to more efficient and durable devices.
Published Researchers create new class of materials called 'glassy gels'
(via sciencedaily.com) Original source Researchers have created a new class of materials called 'glassy gels' that are very hard and difficult to break despite containing more than 50% liquid. Coupled with the fact that glassy gels are simple to produce, the material holds promise for a variety of applications.
Published Mirror-image chemicals may revolutionize drug delivery
(via sciencedaily.com) Original source More than 130 years after cyclodextrins were first discovered and reported, a team of scientists has created chemical mirror images of these complex carbohydrates in the laboratory. This discovery may revolutionize how medications are delivered to patients.
Published Unveiling Telo-seq: A breakthrough in telomere research on aging and cancer
(via sciencedaily.com) Original source Telo-seq -- a new tool -- is bringing telomere science into its modern era. Scientists can finally explore questions about the role of telomeres in aging and cancer that were not accessible with previous methods. The findings will inspire novel telomere-targeting therapeutics for aging-related diseases.
Published Large wildfires create weather that favors more fire
(via sciencedaily.com) Original source A new study shows soot from large wildfires in California traps sunlight, making days warmer and drier than they ought to be.
Published Custom-made molecules designed to be invisible while absorbing near-infrared light
(via sciencedaily.com) Original source Researchers used theoretical calculations assessing electron orbital symmetry to synthesize new molecule designed to be both transparent and colorless while absorbing near-infrared light. This compound demonstrates the first systematic approach to producing such materials and have applications in advanced electronics. This compound also shows semiconducting properties.
Published Molecular sponge for the electronics of the future
(via sciencedaily.com) Original source An international research team has succeeded in developing a new type of material in the rather young research field of covalent organic frameworks. The new two-dimensional polymer is characterized by the fact that its properties can be controlled in a targeted and reversible manner. This has brought the researchers a step closer to the goal of realizing switchable quantum states.