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Categories: Chemistry: Biochemistry, Geoscience: Earth Science
Published Getting dynamic information from static snapshots
(via sciencedaily.com) Original source Researchers have created TopicVelo, a powerful new method of using the static snapshots from scRNA-seq to study how cells and genes change over time. This will help researchers better study how embryos develop, cells differentiate, cancers form, and the immune system reacts.
Published Professor resolves two decades of oxide semiconductor challenges
(via sciencedaily.com) Original source Successful development of high-performance amorphous P-type oxide semiconductor using tellurium-selenium composite oxide.
Published More efficient molecular motor widens potential applications
(via sciencedaily.com) Original source Light-driven molecular motors were first developed nearly 25 years ago. However, making these motors do actual work proved to be a challenge. In a new paper, scientists describe improvements that bring real-life applications closer.
Published Robotic nerve 'cuffs' could help treat a range of neurological conditions
(via sciencedaily.com) Original source Researchers have developed tiny, flexible devices that can wrap around individual nerve fibers without damaging them. The researchers combined flexible electronics and soft robotics techniques to develop the devices, which could be used for the diagnosis and treatment of a range of disorders, including epilepsy and chronic pain, or the control of prosthetic limbs.
Published A shortcut for drug discovery
(via sciencedaily.com) Original source For most human proteins, there are no small molecules known to bind them chemically (so called 'ligands'). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel medicines. Researchers at CeMM, in a collaboration with Pfizer, have now leveraged and scaled a method to measure the binding activity of hundreds of small molecules against thousands of human proteins. This large-scale study revealed tens of thousands of ligand-protein interactions that can now be explored for the development of chemical tools and therapeutics. Moreover, powered by machine learning and artificial intelligence, it allows unbiased predictions of how small molecules interact with all proteins present in living human cells. These groundbreaking results have been published in the journal Science (DOI: 10.1126/science.adk5864), and all generated data and models are freely available for the scientific community.
Published Estimating emissions potential of decommissioned gas wells from shale samples
(via sciencedaily.com) Original source Extracting natural gas from shale formations can provide an abundant, lower-carbon footprint fossil fuel, but also creates concerns over increased methane emissions. Researchers have now developed a new tool that can estimate the emission potential of shale wells after they are no longer active.
Published Nanomaterial that mimics proteins could be basis for new neurodegenerative disease treatments
(via sciencedaily.com) Original source A newly developed nanomaterial that mimics the behavior of proteins could be an effective tool for treating Alzheimer's and other neurodegenerative diseases. The nanomaterial alters the interaction between two key proteins in brain cells -- with a potentially powerful therapeutic effect.
Published Warming Arctic reduces dust levels in parts of the planet
(via sciencedaily.com) Original source Dust can have a huge impact on local air quality, food security, energy supply and public health. Previous studies have found that dust levels are decreasing across India, particularly northern India, the Persian Gulf Coast and much of the Middle East, but the reason has remained unclear. Researchers found that the decrease in dust can be attributed to the Arctic warming much faster than the rest of the planet, a phenomenon known as Arctic amplification. This process destabilizes the jet stream and changes storm tracks and wind patterns over the major sources of dust in West and South Asia.
Published 'Like a nanoscopic Moon lander': Scientists unlock secret of how pyramidal molecules move across surfaces
(via sciencedaily.com) Original source Scientists have watched a molecule move across a graphite surface in unprecedented detail. It turns out this particular molecule moves like a Moon lander -- and the insights hold potential for future nanotechnologies.
Published Towards novel promising perovskite-type ferroelectric materials: High-pressure synthesis of rubidium niobate
(via sciencedaily.com) Original source Researchers have pioneered a breakthrough in ferroelectric material development. They've engineered a novel displacement-type ferroelectric material boasting remarkable dielectric properties. Their achievement includes the successful synthesis of rubidium niobate (RbNbO3), a compound previously deemed challenging to produce under pressures exceeding 40,000 atmospheres. Additionally, they characterized how polarization changes across a wide temperature range during phase transitions. This breakthrough can lead to new design guidelines for ferroelectric materials.
Published The secret to saving old books could be gluten-free glues
(via sciencedaily.com) Original source 'Bookworm' is a cute thing to call a voracious reader, but actual bookworms -- as well as microorganisms and time -- break down the flour pastes commonly used to keep old publications in one piece. Now, researchers have analyzed the proteins in wheat-based glues applied in historic bookbinding to provide insights on their adhesiveness and how they degrade. This information could help conservators restore and preserve treasured tomes for future generations.
Published Unveiling the lionfish invasion in the Mediterranean Sea
(via sciencedaily.com) Original source Researchers have published a comprehensive study on the invasion of lionfish in the Mediterranean Sea, highlighting a rapid spread and the potential ecological impacts. The research shows the lionfish species Pterois miles has significantly expanded its territory in the Mediterranean since the invasion began around ten years ago. The invasive species has established presence in the eastern Mediterranean, with observations now extending to colder waters previously thought to be unsuitable for the species.
Published Human activities have an intense impact on Earth's deep subsurface fluid flow
(via sciencedaily.com) Original source Hydrologists predict human-induced underground fluid fluxes to rise with climate change mitigation strategies like carbon sequestration.
Published Artificial intelligence helps scientists engineer plants to fight climate change
(via sciencedaily.com) Original source Scientists are using artificial intelligence software to analyze plant root systems, laying out a protocol that can be applied to gather data on crop and model plant phenotypes (physical characteristics) more efficiently and with equal or greater accuracy than existing methods.
Published Managing meandering waterways in a changing world
(via sciencedaily.com) Original source Just as water moves through a river, rivers themselves move across the landscape. They carve valleys and canyons, create floodplains and deltas, and transport sediment from the uplands to the ocean.
Published Why can't robots outrun animals?
(via sciencedaily.com) Original source Robotics engineers have worked for decades and invested many millions of research dollars in attempts to create a robot that can walk or run as well as an animal. And yet, it remains the case that many animals are capable of feats that would be impossible for robots that exist today.
Published Pattern formation in the nano-cosmos
(via sciencedaily.com) Original source A new model extends the theory of elastic phase separation towards nanoscopic structures. Such patterns are frequent in biological systems and also used in nano-engineering to create structural color. With their new insights, the scientists can predict the length scale of nanoscopic patterns and thus control them during production.
Published Modeling broader effects of wildfires in Siberia
(via sciencedaily.com) Original source As wildfires in Siberia become more common, global climate modeling estimates significant impacts on climate, air quality, health, and economies in East Asia and across the northern hemisphere.
Published Researchers find oldest undisputed evidence of Earth's magnetic field
(via sciencedaily.com) Original source A new study has recovered a 3.7-billion-year-old record of Earth's magnetic field, and found that it appears remarkably similar to the field surrounding Earth today.
Published Biophysics: Testing how well biomarkers work
(via sciencedaily.com) Original source Researchers have developed a method to determine how reliably target proteins can be labeled using super-resolution fluorescence microscopy.