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Categories: Chemistry: Organic Chemistry, Geoscience: Severe Weather
Published New approach in the synthesis of complex natural substances
(via sciencedaily.com) Original source Many natural substances possess interesting characteristics, and can form the basis of new active compounds in medicine. Terpenes, for example, are a group of substances, some of which are already used in therapies against cancer, malaria or epilepsy. They are found as fragrances in cosmetics or as flavorings in food, and form the basis of new medications: Terpenes are natural substances that occur in plants, insects and sea sponges. They are difficult to produce synthetically. However, chemists are now introducing a new method of synthesis.
Published Researchers create new chemical compound to solve 120-year-old problem
(via sciencedaily.com) Original source Chemists have created a highly reactive chemical compound that has eluded scientists for more than 120 years. The discovery could lead to new drug treatments, safer agricultural products, and better electronics.
Published Scientists solve chemical mystery at the interface of biology and technology
(via sciencedaily.com) Original source Organic electrochemical transistors (OECTs) allow current to flow in devices like implantable biosensors. But scientists long knew about a quirk of OECTs that no one could explain: When an OECT is switched on, there is a lag before current reaches the desired operational level. When switched off, there is no lag. Current drops immediately. Researchers report that they have discovered the reason for this activation lag, and in the process are paving the way to custom-tailored OECTs for a growing list of applications in biosensing, brain-inspired computation and beyond.
Published Research on RNA editing illuminates possible lifesaving treatments for genetic diseases
(via sciencedaily.com) Original source The research explores how CRISPR can be used to edit RNA.
Published Details of hurricane Ian's aftermath captured with new remote sensing method
(via sciencedaily.com) Original source Using aerial imagery data and LiDAR, a study remotely identified the hardest-hit areas of Southwest Florida's Estero Island in the aftermath of Hurricane Ian. Researchers estimated the extent of structural damage and compared pre- and post-storm beach structural changes. They identified 2,427 structures that were impacted. The value of the heavily damaged structures was estimated at more than $200 million. The study has applied an advanced multi-faceted approach that links damage assessment to post-storm change in the structure of barrier islands.
Published When does a conductor not conduct?
(via sciencedaily.com) Original source A new study uncovers a switchable, atomically-thin metal-organic material that could be used in future low-energy electronic technologies. The study shows that electron interactions in this material create an unusual electrically-insulating phase in which electrons are 'frozen'. By reducing the population of electrons, the authors are able to unfreeze the remaining electrons, allowing for controlled transitions between insulating and electrically-conductive phases: the key to the on-off binary operations of classical computing.
Published Getting dynamic information from static snapshots
(via sciencedaily.com) Original source Researchers have created TopicVelo, a powerful new method of using the static snapshots from scRNA-seq to study how cells and genes change over time. This will help researchers better study how embryos develop, cells differentiate, cancers form, and the immune system reacts.
Published Scientists capture X-rays from upward positive lightning
(via sciencedaily.com) Original source Researchers have for the first time recorded X-rays being produced at the beginning of upward positive lightning flashes; an observation that gives important insight into the origins of this rare -- and particularly dangerous -- form of lightning.
Published New offshore wind turbines can take away energy from existing ones
(via sciencedaily.com) Original source Interactions between wind turbines could reduce power output by 30% in proposed offshore wind farm areas along the East Coast, new research has found. In all, the farms could still meet 60% of the electricity demand of New England.
Published A shortcut for drug discovery
(via sciencedaily.com) Original source For most human proteins, there are no small molecules known to bind them chemically (so called 'ligands'). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel medicines. Researchers at CeMM, in a collaboration with Pfizer, have now leveraged and scaled a method to measure the binding activity of hundreds of small molecules against thousands of human proteins. This large-scale study revealed tens of thousands of ligand-protein interactions that can now be explored for the development of chemical tools and therapeutics. Moreover, powered by machine learning and artificial intelligence, it allows unbiased predictions of how small molecules interact with all proteins present in living human cells. These groundbreaking results have been published in the journal Science (DOI: 10.1126/science.adk5864), and all generated data and models are freely available for the scientific community.
Published Nanomaterial that mimics proteins could be basis for new neurodegenerative disease treatments
(via sciencedaily.com) Original source A newly developed nanomaterial that mimics the behavior of proteins could be an effective tool for treating Alzheimer's and other neurodegenerative diseases. The nanomaterial alters the interaction between two key proteins in brain cells -- with a potentially powerful therapeutic effect.
Published The longer spilled oil lingers in freshwater, the more persistent compounds it produces
(via sciencedaily.com) Original source Oil is an important natural resource for many industries, but it can lead to serious environmental damage when accidentally spilled. While large oil spills are highly publicized, every year there are many smaller-scale spills into lakes, rivers and oceans. The longer that oil remains in freshwater, the more chemical changes it undergoes, creating products that can persist in the environment.
Published Warming Arctic reduces dust levels in parts of the planet
(via sciencedaily.com) Original source Dust can have a huge impact on local air quality, food security, energy supply and public health. Previous studies have found that dust levels are decreasing across India, particularly northern India, the Persian Gulf Coast and much of the Middle East, but the reason has remained unclear. Researchers found that the decrease in dust can be attributed to the Arctic warming much faster than the rest of the planet, a phenomenon known as Arctic amplification. This process destabilizes the jet stream and changes storm tracks and wind patterns over the major sources of dust in West and South Asia.
Published The secret to saving old books could be gluten-free glues
(via sciencedaily.com) Original source 'Bookworm' is a cute thing to call a voracious reader, but actual bookworms -- as well as microorganisms and time -- break down the flour pastes commonly used to keep old publications in one piece. Now, researchers have analyzed the proteins in wheat-based glues applied in historic bookbinding to provide insights on their adhesiveness and how they degrade. This information could help conservators restore and preserve treasured tomes for future generations.
Published Hurricanes jeopardize carbon-storing New England forests
(via sciencedaily.com) Original source Many American companies are relying on carbon offsets to reduce their carbon footprint, especially those who have pledged to achieve 'net-zero emissions.' Sequestering carbon in forests is an example of a nature-based solution that is being used to address climate change, but a new study suggests that hurricanes could pose a risk. The results show that a single hurricane may wipe out 5% to 10% of total above-ground forest carbon, through tree damage, in New England.
Published Biophysics: Testing how well biomarkers work
(via sciencedaily.com) Original source Researchers have developed a method to determine how reliably target proteins can be labeled using super-resolution fluorescence microscopy.
Published Shoreline model predicts long-term future of storm protection and sea-level rise
(via sciencedaily.com) Original source Researchers have created a coastal evolution model to analyze how coastal management activities on barrier islands, meant to adapt to sea-level rise, can disrupt natural processes that are keeping the barrier islands above water. Replenishing beaches and clearing over-washed roads may not be the best long term strategy.
Published A chemical mystery solved -- the reaction explaining large carbon sinks
(via sciencedaily.com) Original source A mystery that has puzzled the scientific community for over 50 years has finally been solved. A team has discovered that a certain type of chemical reaction can explain why organic matter found in rivers and lakes is so resistant to degradation.
Published Researchers create artificial cells that act like living cells
(via sciencedaily.com) Original source Researchers describe the steps they took to manipulate DNA and proteins -- essential building blocks of life -- to create cells that look and act like cells from the body. This accomplishment, a first in the field, has implications for efforts in regenerative medicine, drug delivery systems and diagnostic tools.
Published Marginalized communities developed 'disaster subculture' when living through extreme climate events
(via sciencedaily.com) Original source An assistant professor conducted a study in which he lived among one of the poorest, most marginalized communities in Seoul, South Korea. In the ethnographic study, he asked residents how they dealt with extreme heat. He found they tended to accept the conditions, stating there was not much that could be done. That shows people accepted extreme climate events, despite evidence showing this should not be normal, which bodes the argument social work as a field has much to do to help address climate emergencies.