Showing 20 articles starting at article 1
Categories: Biology: Biotechnology
Published Revealing DNA behavior in record time
(via sciencedaily.com) Original source Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process. Biophysicists have developed a technique that speeds up screening of individual DNA molecules at least a thousand times. With this technology, they can measure millions of DNA molecules within a week instead of years to decades.
Published Creature the size of a dust grain found hiding in California's Mono Lake
(via sciencedaily.com) Original source Mono Lake is a beautiful but harsh environment, its salty and arsenic-laced water home to brine shrimp, alkali flies and little else. Scientists recently discovered an unsuspected resident, however, a microscopic creature -- a choanoflagelatte -- that forms colonies that harbor their own unique bacterial microbiomes. The creature, part of the sister group to all animals, could shed light on the evolution of animals' intimate interactions with bacteria and the rise of multicellular life.
Published Engineers design lookalike drug carrier to evade lung's lines of defense
(via sciencedaily.com) Original source Managing hard-to-treat respiratory illnesses like asthma and pulmonary fibrosis just got easier if a new drug-carrying molecule is as sneaky as its inventors think.
Published Next time you beat a virus, thank your microbial ancestors
(via sciencedaily.com) Original source When you get infected with a virus, some of the first weapons your body deploys to fight it were passed down to us from our microbial ancestors billions of years ago. According to new research, two key elements of our innate immune system came from a group of microbes called Asgard archaea.
Published Life from a drop of rain: New research suggests rainwater helped form the first protocell walls
(via sciencedaily.com) Original source New research shows that rainwater could have helped create a meshy wall around protocells 3.8 billion years ago, a critical step in the transition from tiny beads of RNA to every bacterium, plant, animal, and human that ever lived.
Published 'DNA scavengers' can stop some antibiotic resistance from spreading
(via sciencedaily.com) Original source For nearly a century, scientists have waged war on antibiotic-resistant microbes. Researchers say they've found a new way to prevent it -- by unleashing 'DNA scavengers' in wastewater treatment plants.
Published Engineered Bacteria make thermally stable plastics similar to polystyrene and PET
(via sciencedaily.com) Original source Bioengineers around the world have been working to create plastic-producing microbes that could replace the petroleum-based plastics industry. Now, researchers have overcome a major hurdle: getting bacteria to produce polymers that contain ring-like structures, which make the plastics more rigid and thermally stable. Because these molecules are usually toxic to microorganisms, the researchers had to construct a novel metabolic pathway that would enable the E. coli bacteria to both produce and tolerate the accumulation of the polymer and the building blocks it is composed of. The resulting polymer is biodegradable and has physical properties that could lend it to biomedical applications such as drug delivery, though more research is needed.
Published Benefits and downside of fasting
(via sciencedaily.com) Original source Researchers identified a signaling pathway in mice that boosts intestinal stem cells' regeneration abilities after fasting. When cancerous mutations occurred during this regenerative period, mice were more likely to develop early-stage intestinal tumors.
Published Surprising mechanism for removing dead cells identified
(via sciencedaily.com) Original source A tandem signaling process turns ordinary cells into an efficient cleanup crew.
Published Researchers teaching artificial intelligence about frustration in protein folding
(via sciencedaily.com) Original source Scientists have found a new way to predict how proteins change their shape when they function, which is important for understanding how they work in living systems. While recent artificial intelligence (AI) technology has made it possible to predict what proteins look like in their resting state, figuring out how they move is still challenging because there is not enough direct data from experiments on protein motions to train the neural networks.
Published New worm study paves way for better RNA-based drugs to treat human disease
(via sciencedaily.com) Original source Researchers have discovered RNA mechanisms that may lead to more effective, durable and targeted treatments for conditions like high cholesterol, liver diseases and cancers.
Published Deadly sea snail toxin could be key to making better medicines
(via sciencedaily.com) Original source Scientists are finding clues for how to treat diabetes and hormone disorders in an unexpected place: a toxin from one of the most venomous animals on the planet.
Published Scientists discover new code governing gene activity
(via sciencedaily.com) Original source A newly discovered code within DNA -- coined 'spatial grammar' -- holds a key to understanding how gene activity is encoded in the human genome. This breakthrough finding revealed a long-postulated hidden spatial grammar embedded in DNA. The research could reshape scientists' understanding of gene regulation and how genetic variations may influence gene expression in development or disease.
Published Researchers uncover the secrets of 'plant puberty'
(via sciencedaily.com) Original source Researchers have identified the genetic changes linked to why plants go through a developmental change similar to 'puberty' at different rates, a discovery which could lead to better crop nutrition.
Published Peering into the mind of artificial intelligence to make better antibiotics
(via sciencedaily.com) Original source Artificial intelligence (AI) has exploded in popularity as of late. But just like a human, it's hard to read an AI model's mind. Explainable AI (XAI) could help us do just that by providing justification for a model's decisions. And now, researchers are using XAI to scrutinize predictive AI models more closely, which could help make better antibiotics.
Published New insights on how bird flu crosses the species barrier
(via sciencedaily.com) Original source The avian influenza virus needs to mutate to cross the species barrier and to infect and replicate within mammalian cells. Scientists have now deciphered the structure of the avian influenza virus's polymerase when it interacts with a human protein essential for the virus to replicate within the cell. The structure of this replication complex provides important information about the mutations that avian influenza polymerase must undergo to adapt to mammals, including humans. These results can help scientists monitor the evolution and adaptability of bird flu strains, such as H5N1 or H7N9, towards infecting other species.
Published Searching old stem cells that stay young forever
(via sciencedaily.com) Original source The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists have now identified possible candidates for multipotent stem cells in the sea anemone for the first time. These stem cells are regulated by evolutionary highly conserved genes.
Published Preliminary study shows potential of Manuka honey as a nutraceutical for breast cancer
(via sciencedaily.com) Original source A new study found that Manuka honey could potentially be an alternative, natural option for breast cancer prevention and treatment -- particularly for estrogen receptor (ER)-positive breast cancer, the most common subtype of breast cancer that accounts for about 70-80% of all breast cancer cases.
Published Ancient DNA reveals Indigenous dog lineages found at Jamestown, Virginia
(via sciencedaily.com) Original source Previous scientific studies have indicated that North American dog lineages were replaced with European ones between 1492 and the present day. To better understand the timing of this replacement, researchers sequenced mitochondrial DNA from archaeological dogs. Their findings suggest a complex social history of dogs during the early colonial period.
Published Knocking out one key gene leads to autistic traits
(via sciencedaily.com) Original source Hyperactivity, repetitive behavior, and language deficits all appeared in the mice, highlighting an unexpected role the cerebellum seems to play in autism.