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Categories: Chemistry: Organic Chemistry, Geoscience: Earth Science
Published Climate change and mercury pollution stressed plants for millions of years



The link between massive flood basalt volcanism and the end-Triassic (201 million years ago) mass-extinction is commonly accepted. However, exactly how volcanism led to the collapse of ecosystems and the extinction of entire families of organisms is difficult to establish. Extreme climate change from the release of carbon dioxide, degradation of the ozone layer due to the injection of damaging chemicals, and the emissions of toxic pollutants, are all seen as contributing factors. One toxic element stands out: mercury.
Published Scientists solve chemical mystery at the interface of biology and technology



Organic electrochemical transistors (OECTs) allow current to flow in devices like implantable biosensors. But scientists long knew about a quirk of OECTs that no one could explain: When an OECT is switched on, there is a lag before current reaches the desired operational level. When switched off, there is no lag. Current drops immediately. Researchers report that they have discovered the reason for this activation lag, and in the process are paving the way to custom-tailored OECTs for a growing list of applications in biosensing, brain-inspired computation and beyond.
Published Research on RNA editing illuminates possible lifesaving treatments for genetic diseases



The research explores how CRISPR can be used to edit RNA.
Published When does a conductor not conduct?



A new study uncovers a switchable, atomically-thin metal-organic material that could be used in future low-energy electronic technologies. The study shows that electron interactions in this material create an unusual electrically-insulating phase in which electrons are 'frozen'. By reducing the population of electrons, the authors are able to unfreeze the remaining electrons, allowing for controlled transitions between insulating and electrically-conductive phases: the key to the on-off binary operations of classical computing.
Published Getting dynamic information from static snapshots



Researchers have created TopicVelo, a powerful new method of using the static snapshots from scRNA-seq to study how cells and genes change over time. This will help researchers better study how embryos develop, cells differentiate, cancers form, and the immune system reacts.
Published A shortcut for drug discovery



For most human proteins, there are no small molecules known to bind them chemically (so called 'ligands'). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel medicines. Researchers at CeMM, in a collaboration with Pfizer, have now leveraged and scaled a method to measure the binding activity of hundreds of small molecules against thousands of human proteins. This large-scale study revealed tens of thousands of ligand-protein interactions that can now be explored for the development of chemical tools and therapeutics. Moreover, powered by machine learning and artificial intelligence, it allows unbiased predictions of how small molecules interact with all proteins present in living human cells. These groundbreaking results have been published in the journal Science (DOI: 10.1126/science.adk5864), and all generated data and models are freely available for the scientific community.
Published Nanomaterial that mimics proteins could be basis for new neurodegenerative disease treatments



A newly developed nanomaterial that mimics the behavior of proteins could be an effective tool for treating Alzheimer's and other neurodegenerative diseases. The nanomaterial alters the interaction between two key proteins in brain cells -- with a potentially powerful therapeutic effect.
Published The longer spilled oil lingers in freshwater, the more persistent compounds it produces



Oil is an important natural resource for many industries, but it can lead to serious environmental damage when accidentally spilled. While large oil spills are highly publicized, every year there are many smaller-scale spills into lakes, rivers and oceans. The longer that oil remains in freshwater, the more chemical changes it undergoes, creating products that can persist in the environment.
Published Warming Arctic reduces dust levels in parts of the planet



Dust can have a huge impact on local air quality, food security, energy supply and public health. Previous studies have found that dust levels are decreasing across India, particularly northern India, the Persian Gulf Coast and much of the Middle East, but the reason has remained unclear. Researchers found that the decrease in dust can be attributed to the Arctic warming much faster than the rest of the planet, a phenomenon known as Arctic amplification. This process destabilizes the jet stream and changes storm tracks and wind patterns over the major sources of dust in West and South Asia.
Published The secret to saving old books could be gluten-free glues



'Bookworm' is a cute thing to call a voracious reader, but actual bookworms -- as well as microorganisms and time -- break down the flour pastes commonly used to keep old publications in one piece. Now, researchers have analyzed the proteins in wheat-based glues applied in historic bookbinding to provide insights on their adhesiveness and how they degrade. This information could help conservators restore and preserve treasured tomes for future generations.
Published Unveiling the lionfish invasion in the Mediterranean Sea



Researchers have published a comprehensive study on the invasion of lionfish in the Mediterranean Sea, highlighting a rapid spread and the potential ecological impacts. The research shows the lionfish species Pterois miles has significantly expanded its territory in the Mediterranean since the invasion began around ten years ago. The invasive species has established presence in the eastern Mediterranean, with observations now extending to colder waters previously thought to be unsuitable for the species.
Published Human activities have an intense impact on Earth's deep subsurface fluid flow



Hydrologists predict human-induced underground fluid fluxes to rise with climate change mitigation strategies like carbon sequestration.
Published Artificial intelligence helps scientists engineer plants to fight climate change



Scientists are using artificial intelligence software to analyze plant root systems, laying out a protocol that can be applied to gather data on crop and model plant phenotypes (physical characteristics) more efficiently and with equal or greater accuracy than existing methods.
Published Managing meandering waterways in a changing world



Just as water moves through a river, rivers themselves move across the landscape. They carve valleys and canyons, create floodplains and deltas, and transport sediment from the uplands to the ocean.
Published Modeling broader effects of wildfires in Siberia



As wildfires in Siberia become more common, global climate modeling estimates significant impacts on climate, air quality, health, and economies in East Asia and across the northern hemisphere.
Published Researchers find oldest undisputed evidence of Earth's magnetic field



A new study has recovered a 3.7-billion-year-old record of Earth's magnetic field, and found that it appears remarkably similar to the field surrounding Earth today.
Published Biophysics: Testing how well biomarkers work



Researchers have developed a method to determine how reliably target proteins can be labeled using super-resolution fluorescence microscopy.
Published High-resolution lidar sees birth zone of cloud droplets



Scientists demonstrated the first-ever remote observations of the fine-scale structure at the base of clouds. The results show that the air-cloud interface is a transition zone where aerosol particles suspended in Earth's atmosphere give rise to the droplets that ultimately form clouds. The research will enable scientists to gain insight into how changes in atmospheric aerosol levels could affect clouds and climate.
Published A chemical mystery solved -- the reaction explaining large carbon sinks



A mystery that has puzzled the scientific community for over 50 years has finally been solved. A team has discovered that a certain type of chemical reaction can explain why organic matter found in rivers and lakes is so resistant to degradation.
Published Critical minerals recovery from electronic waste



A nontoxic separation process recovers critical minerals from electronic scrap waste.