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Categories: Anthropology: General, Chemistry: Organic Chemistry

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An international team of researchers analyzed the genomes of 180 indigenous Africans from a dozen ethnically, culturally, linguistically, and geographically diverse populations. The results shed light on the origin of modern humans, historical migrations, linguistic evolution, and local adaptation, and lay the groundwork for more people to benefit from precision medicine.

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A team of researchers has made a discovery that may have implications for therapeutic gene editing strategies, cancer diagnostics and therapies and other advancements in biotechnology.

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A world-first model of paleoclimate and hydrology in Iran has highlighted favourable routes for Neanderthals and modern human expansions eastwards into Asia. The findings reveal that multiple humid periods in ancient Iran led to the expansions of human populations, opening dispersal route across the region, and the possible interactions of species such as Neanderthals and our own Homo sapiens.

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Quantum effects can play an important role in chemical reactions. Physicists have now observed a quantum mechanical tunneling reaction in experiments. The observation can also be described exactly in theory. The scientists provide an important reference for this fundamental effect in chemistry. It is the slowest reaction with charged particles ever observed.

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A new study reports on genomic data from a 23,000-year-old individual who lived in what was probably the warmest place of Europe at the peak of the last Ice Age. The oldest human genome recovered from the southern tip of Spain adds an important piece of the puzzle to the genetic history of Europe.

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Certain diseases, including Alzheimer's, are currently considered 'undruggable' because traditional small molecule drugs can't interfere with the proteins responsible for the illnesses. But a new technique that specifically targets and breaks apart certain proteins -- rather than just interfering with them -- may offer a pathway toward treatment. Researchers have now designed a compound that targets and breaks down a post-translationally modified protein closely associated with Alzheimer's disease.

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Engineers devised a way to purify protein drugs during manufacturing. Their approach, which uses nanoparticles to rapidly crystallize proteins, could help make protein drugs more affordable and accessible, especially in developing countries.

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In 2011, scientists recorded a previously unknown feeding strategy in whales around the world. Now, researchers in Australia think they may have found evidence of this behaviour being described in ancient accounts of sea creatures, recorded more than 2,000 years ago. They believe that misunderstandings of these descriptions contributed to myths about medieval sea monsters. Whales are known lunge at their prey when feeding, but recently whales have been spotted at the surface of the water with their jaws open at right angles, waiting for shoals of fish to swim into their mouths. A clip of this strategy was captured in 2021 and went viral on Instagram. This strategy seems to work for the whales because the fish think they have found a place to shelter from predators, not realising they are swimming into danger. It's not known why this strategy has only recently been identified, but scientists speculate that it's a result of changing environmental conditions -- or that whales are being more closely monitored than ever before by drones and other modern technologies.

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Cartilaginous fish have changed much more in the course of their evolutionary history than previously believed. Evidence for this thesis has been provided by new fossils of a ray-like shark, Protospinax annectans, which demonstrate that sharks were already highly evolved in the Late Jurassic.

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A new hybrid hydrogel that safely delivers stem cells to brain injury sites in mice has been developed. This solves a major challenge -- keeping stem cells alive for long enough to evolve into the cells required to create new tissue after insertion into a damaged part of the body.

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Researchers have succeeded in producing very special catalysts, known as 'Lewis superacids', which can be used to break strong chemical bonds and speed up reactions. The production of these substances has, until now, proven extremely difficult. The chemists' discovery enables non-biodegradable fluorinated hydrocarbons, similar to Teflon, and possibly even climate-damaging greenhouse gases, such as sulphur hexafluoride, to be converted back into sustainable chemicals.

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Chaotic behavior is typically known from large systems: for example, from weather, from asteroids in space that are simultaneously attracted by several large celestial bodies, or from swinging pendulums that are coupled together. On the atomic scale, however, one does normally not encounter chaos -- other effects predominate. Now scientists have been able to detect clear indications of chaos on the nanometer scale -- in chemical reactions on tiny rhodium crystals.

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By simulating early Earth conditions in the lab, researchers have found that without specific amino acids, ancient proteins would not have known how to evolve into everything alive on the planet today -- including plants, animals, and humans.

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Scientists who study the origins and evolution of the plague have examined hundreds of ancient human teeth from Denmark, seeking to address longstanding questions about its arrival, persistence and spread within Scandinavia.

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A series of new stable, porous materials that capture and separate benzene have been developed.

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A team has developed a method for selectively manipulating genetically engineered cells with ultrasound.

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The boundaries between biology and technology are becoming blurred. Researchers have now successfully grown electrodes in living tissue using the body's molecules as triggers. The result paves the way for the formation of fully integrated electronic circuits in living organisms.

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An air filter made out of corn protein instead of petroleum products can concurrently capture small particulates as well as toxic chemicals like formaldehyde that current air filters can't. The research could lead to better air purifiers, particularly in regions of the world that suffer from very poor air quality. The more environmentally friendly air filter was able to simultaneously capture 99.5% of small particulate matter, similar to commercial HEPA filters, and 87% of formaldehyde, which is higher than specially designed air filters for those types of toxics.

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Theoretical chemists have developed a theory that can predict the threshold at which quantum dynamics switches from 'orderly' to 'random,' as shown through research using large-scale computations on photosynthesis models.

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Researchers create a network of interacting proteins -- or interactome -- to aid drug discovery.