Anthropology: Early Humans Anthropology: General Offbeat: General Offbeat: Paleontology and Archeology
Published

Neanderthal gene variants associated with greater pain sensitivity      (via sciencedaily.com)     Original source 

People who carry three gene variants that have been inherited from Neanderthals are more sensitive to some types of pain, according to a new study.

Biology: Biochemistry Biology: Evolutionary Biology: General Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals Paleontology: Fossils Paleontology: General
Published

Ginger pigment molecules found in fossil frogs      (via sciencedaily.com) 

Palaeontologists discover molecular evidence of phaeomelanin, the pigment that produces ginger coloration. Phaeomelanin is now toxic to animals – this discovery may be first step in understand its evolution. 

Chemistry: Biochemistry Chemistry: Organic Chemistry Computer Science: General Mathematics: Modeling
Published

Researchers create a neural network for genomics -- one that explains how it achieves accurate predictions      (via sciencedaily.com)     Original source 

A team of computer scientists has created a neural network that can explain how it reaches its predictions. The work reveals what accounts for the functionality of neural networks--the engines that drive artificial intelligence and machine learning--thereby illuminating a process that has largely been concealed from users.   

Offbeat: General Offbeat: Paleontology and Archeology Paleontology: General
Published

Oldest fossil human footprints in North America confirmed      (via sciencedaily.com)     Original source 

New research reaffirms that human footprints found in White Sands National Park, NM, date to the Last Glacial Maximum, placing humans in North America thousands of years earlier than once thought.  In September 2021, scientists announced that ancient human footprints discovered in White Sands National Park were between 21,000 and 23,000 years old. This discovery pushed the known date of human presence in North America back by thousands of years and implied that early inhabitants and megafauna co-existed for several millennia before the terminal Pleistocene extinction event. In a follow-up study, researchers used two new independent approaches to date the footprints, both of which resulted in the same age range as the original estimate. 

Chemistry: General Chemistry: Organic Chemistry Energy: Fossil Fuels Environmental: General Geoscience: Geochemistry
Published

Discovery made about Fischer Tropsch process could help improve fuel production      (via sciencedaily.com)     Original source 

A fundamental discovery about the Fischer Tropsch process, a catalytic reaction used in industry to convert coal, natural gas or biomass to liquid fuels, could someday allow for more efficient fuel production. Researchers discovered previously unknown self-sustained oscillations in the Fischer Tropsch process. They found that unlike many catalytic reactions which have one steady state, this reaction periodically moves back and forth from a high to a low activity state. The discovery means that these well-controlled oscillatory states might be used in the future to control the reaction rate and the yields of desired products.

Chemistry: Biochemistry Chemistry: General Chemistry: Organic Chemistry Engineering: Nanotechnology Offbeat: General
Published

The medicine of the future could be artificial life forms      (via sciencedaily.com)     Original source 

Imagine a life form that doesn't resemble any of the organisms found on the tree of life. One that has its own unique control system, and that a doctor would want to send into your body. It sounds like a science fiction movie, but according to nanoscientists, it can—and should—happen in the future.

Chemistry: Biochemistry Chemistry: Organic Chemistry Engineering: Graphene
Published

Graphene oxide reduces the toxicity of Alzheimer's proteins      (via sciencedaily.com)     Original source 

A probable early driver of Alzheimer's disease is the accumulation of molecules called amyloid peptides. These cause cell death, and are commonly found in the brains of Alzheimer’s patients. Researchers have now shown that yeast cells that accumulate these misfolded amyloid peptides can recover after being treated with graphene oxide nanoflakes.

Chemistry: Biochemistry Chemistry: Organic Chemistry Engineering: Nanotechnology
Published

Bioengineering breakthrough increases DNA detection sensitivity by 100 times      (via sciencedaily.com)     Original source 

Researchers have pushed forward the boundaries of biomedical engineering one hundredfold with a new method for DNA detection with unprecedented sensitivity.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: General Chemistry: Organic Chemistry
Published

Small but mighty new gene editor      (via sciencedaily.com)     Original source 

A new CRISPR-based gene-editing tool has been developed which could lead to better treatments for patients with genetic disorders. The tool is an enzyme, AsCas12f, which has been modified to offer the same effectiveness but at one-third the size of the Cas9 enzyme commonly used for gene editing. The compact size means that more of it can be packed into carrier viruses and delivered into living cells, making it more efficient.

Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

A deep look into the progression of Parkinson's Disease      (via sciencedaily.com)     Original source 

Scientists have used cutting-edge imaging techniques to shed light on the progression of Parkinson's disease by studying how the main culprit, the protein alpha-synuclein, disrupts cellular metabolism.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

An advance in cryo-EM could be a significant boon for research on potential cancer therapies      (via sciencedaily.com)     Original source 

A technology called cryo-electron microscopy enables scientists to see the atomic structure of biological molecules in high resolution. But to date, it has been ineffective for imaging small molecules. A team of biochemists devised a solution that makes it possible to hold small protein molecules in place while they're being imaged, which will enable cryo-EM to produce much clearer images of such molecules. The advance is significant because small and medium-sized protein molecules are an area of focus in research on potential new drugs for cancer and other diseases.

Chemistry: Biochemistry Chemistry: General Chemistry: Inorganic Chemistry Chemistry: Organic Chemistry
Published

Toxic formaldehyde's dual nature to be probed with new chemical tool      (via sciencedaily.com)     Original source 

Newly developed ompounds aim to reveal the dual nature of formaldehyde, a chemical that is known to cause cancer but is also believed to play important roles in our biology.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: General Chemistry: Organic Chemistry
Published

Tiny CRISPR tool could help shred viruses      (via sciencedaily.com)     Original source 

Scientists mapped out the three-dimensional structure of one of the smallest known CRISPR-Cas13 systems then used that knowledge to modify its structure and improve its accuracy.

Chemistry: Biochemistry Chemistry: Organic Chemistry Engineering: Nanotechnology Offbeat: General
Published

Strength is in this glass's DNA      (via sciencedaily.com)     Original source 

Scientists were able to fabricate a pure form of glass and coat specialized pieces of DNA with it to create a material that was not only stronger than steel, but incredibly lightweight.

Chemistry: General Chemistry: Inorganic Chemistry Chemistry: Organic Chemistry Chemistry: Thermodynamics
Published

Separating molecules requires lots of energy. This new, heat-resistant membrane could change that      (via sciencedaily.com)     Original source 

A research team has created a new, heat-resistant membrane that can withstand harsh environments -- high temperatures, high pressure and complex chemical solvents -- associated with industrial separation processes. It could eventually be used as a less energy intensive alternative to distillation and other industrial processes that separate molecules that ultimately serve as ingredients in medicine, chemicals and other products.

Chemistry: General Chemistry: Inorganic Chemistry Chemistry: Organic Chemistry Energy: Alternative Fuels Environmental: General Geoscience: Geochemistry Physics: Optics
Published

How organic solar cells could become significantly more efficient      (via sciencedaily.com)     Original source 

The sun sends enormous amounts of energy to the earth. Nevertheless, some of it is lost in solar cells. This is an obstacle in the use of organic solar cells, especially for those viable in innovative applications. A key factor in increasing their performance: Improved transport of the solar energy stored within the material. Now a research group has shown that certain organic dyes can help build virtual highways for the energy.

Chemistry: Biochemistry Chemistry: General Chemistry: Organic Chemistry Computer Science: General Computer Science: Virtual Reality (VR) Mathematics: Modeling
Published

Drug discovery on an unprecedented scale      (via sciencedaily.com) 

Boosting virtual screening with machine learning allowed for a 10-fold time reduction in the processing of 1.56 billion drug-like molecules. Researchers teamed up with industry and supercomputers to carry out one of the world's largest virtual drug screens.

Chemistry: Organic Chemistry Energy: Alternative Fuels Energy: Fossil Fuels Engineering: Graphene
Published

Efficient fuel-molecule sieving using graphene      (via sciencedaily.com) 

A research team has successfully developed a new method that can prevent the crossover of large fuel molecules and suppress the degradation of electrodes in advanced fuel cell technology using methanol or formic acid. The successful sieving of the fuel molecules is achieved via selective proton transfers due to steric hindrance on holey graphene sheets that have chemical functionalization and act as proton-exchange membranes.