Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

A new way to develop drugs without side effects      (via sciencedaily.com)     Original source 

Have you ever wondered how drugs reach their targets and achieve their function within our bodies? If a drug molecule or a ligand is a message, an inbox is typically a receptor in the cell membrane. One such receptor involved in relaying molecular signals is a G protein-coupled receptor (GPCR). About one-third of existing drugs work by controlling the activation of this protein. Researchers now reveal a new way of activating GPCR by triggering shape changes in the intracellular region of the receptor. This new process can help researchers design drugs with fewer or no side effects.

Archaeology: General Ecology: Nature Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals Paleontology: Dinosaurs Paleontology: General
Published

New dino, 'Iani,' was face of a changing planet      (via sciencedaily.com)     Original source 

A newly discovered plant-eating dinosaur may have been a species' 'last gasp' during a period when Earth's warming climate forced massive changes to global dinosaur populations.

Chemistry: General Chemistry: Inorganic Chemistry Chemistry: Organic Chemistry
Published

More complex than expected: Catalysis under the microscope      (via sciencedaily.com)     Original source 

Usually, catalytic reactions are analyzed by checking which chemicals go into a chemical reactor and which come out. But as it turns out, in order to properly understand and optimize catalysts, much more information is necessary. Scientists developed methods to watch catalytic reactions with micrometer resolution under the microscope -- and the process is much more complex than previously thought.

Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

Illuminating the molecular ballet in living cells      (via sciencedaily.com)     Original source 

Researchers have developed one of the world's fastest cameras capable of detecting fluorescence from single molecules.

Chemistry: General Chemistry: Inorganic Chemistry Chemistry: Organic Chemistry Physics: Optics
Published

Flat fullerene fragments attractive to electrons      (via sciencedaily.com)     Original source 

Researchers have gained new insights into the unique chemical properties of spherical molecules composed entirely of carbon atoms, called fullerenes. They did it by making flat fragments of the molecules, which surprisingly retained and even enhanced some key chemical properties.

Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

Lab-grown mini lungs could accelerate the study of respiratory diseases      (via sciencedaily.com)     Original source 

Researchers have collaborated to refine a cell culture technology platform that grows genetically identical lung buds from human embryonic stem cells.

Biology: Biochemistry Biology: Cell Biology Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: General Chemistry: Inorganic Chemistry Chemistry: Organic Chemistry Offbeat: Computers and Math Offbeat: General Offbeat: Plants and Animals
Published

A protein mines, sorts rare earths better than humans, paving way for green tech      (via sciencedaily.com)     Original source 

Rare earth elements, like neodymium and dysprosium, are a critical component to almost all modern technologies, from smartphones to hard drives, but they are notoriously hard to separate from the Earth's crust and from one another. Scientists have discovered a new mechanism by which bacteria can select between different rare earth elements, using the ability of a bacterial protein to bind to another unit of itself, or 'dimerize,' when it is bound to certain rare earths, but prefer to remain a single unit, or 'monomer,' when bound to others.

Anthropology: Early Humans Anthropology: General Biology: Biochemistry Biology: Evolutionary Biology: General Biology: Genetics Ecology: Extinction Ecology: Nature Offbeat: Earth and Climate Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals Paleontology: Fossils
Published

Geneticists discover hidden 'whole genome duplication' that may explain why some species survived mass extinctions      (via sciencedaily.com)     Original source 

Geneticists have unearthed a major event in the ancient history of sturgeons and paddlefish that has significant implications for the way we understand evolution. They have pinpointed a previously hidden 'whole genome duplication' (WGD) in the common ancestor of these species, which seemingly opened the door to genetic variations that may have conferred an advantage around the time of a major mass extinction some 200 million years ago.

Chemistry: General Chemistry: Inorganic Chemistry Chemistry: Organic Chemistry
Published

Crossing the ring: New method enables C-H activation across saturated carbocycles      (via sciencedaily.com)     Original source 

Chemists add another powerful tool to their 'molecular editing' toolkit for crafting pharmaceuticals and other valuable compounds.

Biology: Biochemistry Biology: Cell Biology Biology: Evolutionary Biology: General Biology: Genetics Chemistry: Biochemistry Chemistry: Organic Chemistry Physics: Optics
Published

Evolution driving improvements in racehorse speed      (via sciencedaily.com)     Original source 

A new study has found that genetic improvement is underlying the increasing speed of Britain's thoroughbreds. This contrasts with earlier studies that suggested racehorses were showing no genetic improvement in response to selection by breeders.

Biology: Biochemistry Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals Paleontology: Dinosaurs Paleontology: Fossils Paleontology: General
Published

107-million-year-old pterosaur bones: Oldest in Australia      (via sciencedaily.com)     Original source 

A team of researchers have confirmed that 107-million-year-old pterosaur bones discovered more than 30 years ago are the oldest of their kind ever found in Australia, providing a rare glimpse into the life of these powerful, flying reptiles that lived among the dinosaurs.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry Engineering: Nanotechnology Offbeat: Computers and Math Offbeat: General Offbeat: Plants and Animals
Published

Protein-based nano-'computer' evolves in ability to influence cell behavior      (via sciencedaily.com)     Original source 

The first protein-based nano-computing agent that functions as a circuit has been created. The milestone puts them one step closer to developing next-generation cell-based therapies to treat diseases like diabetes and cancer.

Biology: Biochemistry Ecology: Animals Ecology: Endangered Species Ecology: Extinction Ecology: Nature Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals Paleontology: Early Mammals and Birds Paleontology: Fossils Paleontology: General
Published

Fossils of a saber-toothed top predator reveal a scramble for dominance leading up to 'the Great Dying'      (via sciencedaily.com)     Original source 

A tiger-sized saber-toothed creature called Inostrancevia has previously only been found in Russia. But scientists have discovered its fossils in South Africa, suggesting that it migrated 7,000 miles across the supercontinent Pangaea during the world's worst mass extinction 252 million years ago. Heading to South Africa allowed it to fill a gap in a faraway ecosystem that had lost its top predators.

Biology: Biochemistry Biology: Evolutionary Biology: General Biology: Marine Biology: Zoology Ecology: Extinction Ecology: Nature Ecology: Sea Life Offbeat: Earth and Climate Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals Paleontology: Dinosaurs Paleontology: General
Published

Fossil of mosasaur with bizarre 'screwdriver teeth' found in Morocco      (via sciencedaily.com)     Original source 

Scientists have discovered a new species of mosasaur, a sea-dwelling lizard from the age of the dinosaurs, with strange, ridged teeth unlike those of any known reptile. Along with other recent finds from Africa, it suggests that mosasaurs and other marine reptiles were evolving rapidly up until 66 million years ago, when they were wiped out by an asteroid along with the dinosaurs and around 90% of all species on Earth.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: General Chemistry: Organic Chemistry Energy: Alternative Fuels Energy: Fossil Fuels Energy: Technology Environmental: General Environmental: Water Geoscience: Environmental Issues Geoscience: Geochemistry
Published

Watch these cells rapidly create protrusions for exploration and movement      (via sciencedaily.com)     Original source 

In order to move, cells must be able to rapidly change shape. A team of researchers show that cells achieve this by storing extra 'skin' in folds and bumps on their surface. This cell surface excess can be rapidly deployed to cover temporary protrusions and then folded away for next time.