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Categories: Chemistry: Organic Chemistry
Published Converting wastewater to fertilizer with fungal treatment
(via sciencedaily.com) Original source Creating fertilizers from organic waste can help reduce the consumption of fossil fuels and promote sustainable production. One way of doing this is through hydrothermal liquefaction (HTL), which converts biomass into biocrude oil through a high-temperature, high-pressure process. Two studies explore the use of a fungal treatment to convert the leftover wastewater into fertilizer for agricultural crops.
Published Microbes found to destroy certain 'forever chemicals'
(via sciencedaily.com) Original source An environmental engineering team has discovered that specific bacterial species can cleave the strong fluorine-to-carbon bond certain kinds of 'forever chemical' water pollutants, offering promise for low-cost treatments of contaminated drinking water.
Published A new addition to the CRISPR toolbox: Teaching the gene scissors to detect RNA
(via sciencedaily.com) Original source CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers have now expanded this extensive toolbox further. Their novel method, called PUMA, enables the detection of RNA with Cas12 nucleases, which naturally target DNA. PUMA promises a wide range of applications and high accuracy.
Published Transporting precious cargo using the body's own delivery system
(via sciencedaily.com) Original source Delivery systems in body continuously move materials between cells. Hijacking these systems allowed scientists to improve loading and delivery of therapeutic proteins. Biophysical principles could be used to enable more cost-effective loading of biological cargo into cell-derived delivery systems. Engineered molecules loaded up to 240 times more protein than other loading methods.
Published Crystals from radioactive metal actinium
(via sciencedaily.com) Original source Researchers grew crystals containing actinium and illuminated them with X-rays to learn how the radioactive metal binds with other elements. That information could help design better cancer treatments.
Published A better way to make RNA drugs
(via sciencedaily.com) Original source RNA drugs are the next frontier of medicine, but manufacturing them requires an expensive and labor-intensive process that limits production and produces metric tons of toxic chemical waste. Researchers report a new, enzyme-based RNA synthesis method that can produce strands of RNA with both natural and modified nucleotides without the environmental hazards.
Published Scientists create computer program that 'paints' the structure of molecules in the style of Piet Mondrian
(via sciencedaily.com) Original source Scientists have created a computer program that 'paints' the structure of molecules in the style of famous Dutch artist, Piet Mondrian. Researchers are opening eyes and minds to the beauty of molecular structure, as well as posing new questions about the form and function of the molecules themselves.
Published Nanoplastics and 'forever chemicals' disrupt molecular structures, functionality
(via sciencedaily.com) Original source Researchers have made significant inroads in understanding how nanoplastics and per- and polyfluoroalkyl substances (PFAS) -- commonly known as forever chemicals -- disrupt biomolecular structure and function. The work shows that the compounds can alter proteins found in human breast milk and infant formulas -- potentially causing developmental issues downstream.
Published Atlas of proteins reveals inner workings of cells
(via sciencedaily.com) Original source Researchers discover how proteins behave inside cells using AI, which has the potential to guide drug design.
Published Researchers show promising material for solar energy gets its curious boost from entropy
(via sciencedaily.com) Original source Researchers discovered a microscopic mechanism that solves in part the outstanding performance achieved by a new class of organic semiconductors known as non-fullerene acceptors (NFAs).
Published Chemistry inspired by one-pot cooking
(via sciencedaily.com) Original source Is it possible to create a new class of materials from very different substances using the 'one-pot synthesis' approach? Chemists explain how they enable the synthesis of such novel materials.
Published Hexagonal perovskite oxides: Electrolytes for next-generation protonic ceramic fuel cells
(via sciencedaily.com) Original source Researchers have identified hexagonal perovskite-related oxides as materials with exceptionally high proton conductivity and thermal stability. Their unique crystal structure and large number of oxygen vacancies enable full hydration and high proton diffusion, making these materials ideal candidates as electrolytes for next-generation protonic ceramic fuel cells that can operate at intermediate temperatures without degradation.
Published Visualizing short-lived intermediate compounds produced during chemical reactions
(via sciencedaily.com) Original source Immobilizing small synthetic molecules inside protein crystals proves to be a promising avenue for studying intermediate compounds formed during chemical reactions, scientists report. By integrating this method with time-resolved serial femtosecond crystallography, they successfully visualized reaction dynamics and rapid structural changes occurring within reaction centers immobilized inside protein crystals. This innovative strategy holds significant potential for the intelligent design of drugs, catalysts, and functional materials.
Published New organic molecule shatters phosphorescence efficiency records and paves way for rare metal-free applications
(via sciencedaily.com) Original source A team has discovered that the new organic molecule thienyl diketone exhibits high-efficiency phosphorescence, achieving a rate over ten times faster than traditional materials. This breakthrough provides new guidelines for developing rare metal-free organic phosphorescent materials, promising advancements in applications like organic EL displays, lighting, and cancer diagnostics.
Published Do genes-in-pieces code for proteins that fold in pieces?
(via sciencedaily.com) Original source A new study offers new insights into the evolution of foldable proteins.
Published Chemists synthesize an improved building block for medicines
(via sciencedaily.com) Original source Research could help drug developers improve the safety profiles of medications and reduce side effects.
Published Using visible light to make pharmaceutical building blocks
(via sciencedaily.com) Original source Chemists have discovered a way to use visible light to synthesize a class of compounds particularly well suited for use in pharmaceuticals. The class of compounds, called azetidines, had been previously identified as a good candidate to build therapeutic drugs, but the compounds are difficult to produce in chemical reactions. Now, a team has developed a method to produce a specific class of azetidines called monocyclic azetidines using visible light and a photocatalyst.
Published Novel spectroscopy technique sheds light on NOx reduction
(via sciencedaily.com) Original source The process that can convert pollution into benign by-products is called selective catalytic reduction, or SCR. Until now, it has been unclear how this reaction actually occurs, and contradictions have long existed between reaction models within the literature. Catalysis researchers used a technology called modulation excitation spectroscopy, or MES, to finally identify the correct pathway.
Published No more stressing out over structural formulas
(via sciencedaily.com) Original source Structural formulas are a source of dread for many students, but they're an essential tool in biology lessons. A study has now shown that the stress levels of students working with chemical formulas are significantly reduced if they are given simple tips on how to deal with these formulas.
Published New materials: Synthetic pathway for promising nitride compounds discovered
(via sciencedaily.com) Original source Chemists have successfully synthesized Ruddlesden-Popper nitrides for the first time, opening the door to new materials with unique properties.