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Categories: Chemistry: Organic Chemistry, Energy: Batteries

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A new CRISPR-based gene-editing tool has been developed which could lead to better treatments for patients with genetic disorders. The tool is an enzyme, AsCas12f, which has been modified to offer the same effectiveness but at one-third the size of the Cas9 enzyme commonly used for gene editing. The compact size means that more of it can be packed into carrier viruses and delivered into living cells, making it more efficient.

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Cheaper, more efficient lithium-ion batteries could be produced by harnessing previously overlooked high pressures generated during the manufacturing process.

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Scientists have used cutting-edge imaging techniques to shed light on the progression of Parkinson's disease by studying how the main culprit, the protein alpha-synuclein, disrupts cellular metabolism.

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A technology called cryo-electron microscopy enables scientists to see the atomic structure of biological molecules in high resolution. But to date, it has been ineffective for imaging small molecules. A team of biochemists devised a solution that makes it possible to hold small protein molecules in place while they're being imaged, which will enable cryo-EM to produce much clearer images of such molecules. The advance is significant because small and medium-sized protein molecules are an area of focus in research on potential new drugs for cancer and other diseases.

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Newly developed ompounds aim to reveal the dual nature of formaldehyde, a chemical that is known to cause cancer but is also believed to play important roles in our biology.

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A research team presented an analysis protocol to evaluate silicon cathode materials applicable to commercialized batteries.

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A pivotal breakthrough in battery technology that has profound implications for our energy future has been achieved.

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Rechargeable battery performance could be improved by a new understanding of how they work at the molecular level. Researchers upend what's known about how rechargeable batteries function.

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Scientists mapped out the three-dimensional structure of one of the smallest known CRISPR-Cas13 systems then used that knowledge to modify its structure and improve its accuracy.

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Scientists were able to fabricate a pure form of glass and coat specialized pieces of DNA with it to create a material that was not only stronger than steel, but incredibly lightweight.

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A research team has created a new, heat-resistant membrane that can withstand harsh environments -- high temperatures, high pressure and complex chemical solvents -- associated with industrial separation processes. It could eventually be used as a less energy intensive alternative to distillation and other industrial processes that separate molecules that ultimately serve as ingredients in medicine, chemicals and other products.

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The sun sends enormous amounts of energy to the earth. Nevertheless, some of it is lost in solar cells. This is an obstacle in the use of organic solar cells, especially for those viable in innovative applications. A key factor in increasing their performance: Improved transport of the solar energy stored within the material. Now a research group has shown that certain organic dyes can help build virtual highways for the energy.

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Copper-based catalysts developed by materials scientists help speed up the rate of carbon dioxide-to-methane conversion.

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Boosting virtual screening with machine learning allowed for a 10-fold time reduction in the processing of 1.56 billion drug-like molecules. Researchers teamed up with industry and supercomputers to carry out one of the world's largest virtual drug screens.

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A research team has successfully developed a new method that can prevent the crossover of large fuel molecules and suppress the degradation of electrodes in advanced fuel cell technology using methanol or formic acid. The successful sieving of the fuel molecules is achieved via selective proton transfers due to steric hindrance on holey graphene sheets that have chemical functionalization and act as proton-exchange membranes.

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To make a gene-editing tool more precise and easier to control, engineers split it into two pieces that only come back together when a third molecule is added.

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A group of researchers have unraveled the mysteries behind a recently identified material -- zirconium nitride (ZrN) -- that helps power clean energy reactions. Their proposed framework will help future designs for transition metal nitrides, paving a path for generating cleaner energy.

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Researchers created nanoribbons made of phosphorus and tiny amounts of arsenic, which they found were able to conduct electricity at temperatures above -140 degrees Celsius, while retaining the highly useful properties of the phosphorus-only ribbons.

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Scientists and industry leaders worldwide are looking for answers on how to make aviation sustainable by 2050 and choosing a viable sustainable fuel is a major sticking point. Aerospace engineers took a full inventory of the options to make a data-driven assessment about how they stack up in comparison. He reviewed over 300 research projects from across different sectors, not just aerospace, to synthesize the ideas and draw conclusions to help direct the dialogue about sustainable aviation toward a permanent solution.

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A research team has achieved a significant breakthrough in the development of a hybrid silicon photocatalyst.