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Categories: Chemistry: Organic Chemistry, Engineering: Biometric
Published New computational strategy boosts the ability of drug designers to target proteins inside the membrane
(via sciencedaily.com) Original source Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, chemists have demonstrated new custom-designed proteins that can efficiently reach these 'intramembrane' targets.
Published A simple and robust experimental process for protein engineering
(via sciencedaily.com) Original source A protein engineering method using simple, cost-effective experiments and machine learning models can predict which proteins will be effective for a given purpose, according to a new study.
Published Scientists develop a rapid gene-editing screen to find effects of cancer mutations
(via sciencedaily.com) Original source Researchers found a way to screen cancer-linked gene mutations much more easily and quickly than existing approaches, using a variant of CRISPR genome-editing known as prime editing.
Published Researchers develop artificial building blocks of life
(via sciencedaily.com) Original source For the first time, scientists have developed artificial nucleotides, the building blocks of DNA, with several additional properties in the laboratory.
Published Researchers develop new machine learning method for modeling of chemical reactions
(via sciencedaily.com) Original source Researchers have used machine learning to create a model that simulates reactive processes in organic materials and conditions.
Published Universal tool for tracking cell-to-cell interactions
(via sciencedaily.com) Original source An updated method for directly observing physical interactions between cells, could allow scientists to one day map every possible cell interaction.
Published New type of nanoparticle makes vaccines more powerful
(via sciencedaily.com) Original source A type of nanoparticle called a metal organic framework (MOF) could be used to deliver vaccines and act as an adjuvant. Researchers find these particles provoke a strong immune response by activating the innate immune system through cell proteins called toll-like receptors.
Published Key advance toward removing common herbicide from groundwater
(via sciencedaily.com) Original source Chemists are closing in on a new tool for tackling the global problem of weedkiller-tainted groundwater.
Published Aluminum nanoparticles make tunable green catalysts
(via sciencedaily.com) Original source A nanotechnology pioneer has uncovered a transformative approach to harnessing the catalytic power of aluminum nanoparticles by annealing them in various gas atmospheres at high temperatures.
Published Using light to precisely control single-molecule devices
(via sciencedaily.com) Original source Researchers flip the switch at the nanoscale by applying light to induce bonding for single-molecule device switching.
Published Researchers closing in on genetic treatments for hereditary lung disease, vision loss
(via sciencedaily.com) Original source Researchers who work with tiny drug carriers known as lipid nanoparticles have developed a new type of material capable of reaching the lungs and the eyes, an important step toward genetic therapy for hereditary conditions like cystic fibrosis and inherited vision loss.
Published 'Like a lab in your pocket' -- new test strips raise game in gene-based diagnostics
(via sciencedaily.com) Original source Biosensing technology developed by engineers has made it possible to create gene test strips that rival conventional lab-based tests in quality.
Published AI-enabled atomic robotic probe to advance quantum material manufacturing
(via sciencedaily.com) Original source Scientists have pioneered a new methodology of fabricating carbon-based quantum materials at the atomic scale by integrating scanning probe microscopy techniques and deep neural networks. This breakthrough highlights the potential of implementing artificial intelligence at the sub-angstrom scale for enhanced control over atomic manufacturing, benefiting both fundamental research and future applications.
Published Turning waste into gold
(via sciencedaily.com) Original source Researchers have recovered gold from electronic waste. Their highly sustainable new method is based on a protein fibril sponge, which the scientists derive from whey, a food industry byproduct.
Published How molecular 'handedness' emerged in early biology
(via sciencedaily.com) Original source Chemists fill a major gap in origin-of-life theories.
Published Researchers develop novel method to photosynthesize hydrogen peroxide using water and air
(via sciencedaily.com) Original source Researchers have developed a microporous covalent organic framework with dense donor-acceptor lattices and engineered linkages for the efficient and clean production of hydrogen peroxide through the photosynthesis process with water and air.
Published Light stimulates a new twist for synthetic chemistry
(via sciencedaily.com) Original source Molecules that are induced by light to rotate bulky groups around central bonds could be developed into photo-activated bioactive systems, molecular switches, and more.
Published Nanocarrier with escape reflex
(via sciencedaily.com) Original source Protein-based drugs must be transported into cells in a way that prevents their immediate degradation. A new approach is intended to ensure that they remain intact only in certain cells, such as cancer cells. A Japanese research team has introduced a nanocarrier that can 'escape' from endosomes before its cargo is destroyed there. This ability to escape is only triggered within the endosomes of certain tumor cells.
Published New disease testing component facilitates lower-cost diagnostics
(via sciencedaily.com) Original source Biomedical researchers have developed a new, less expensive way to detect nuclease digestion -- one of the critical steps in many nucleic acid sensing applications, such as those used to identify COVID-19 and other infectious diseases.
Published Low-Temperature Plasma used to remove E. coli from hydroponically grown crops
(via sciencedaily.com) Original source In a new study, a team sterilized a hydroponic nutrient solution using low-temperature plasma generated from electricity and the oxygen in the atmosphere. This new sterilization technique may allow farmers to grow crops without the use of chemical pesticides, representing an important advance in agricultural technology for sustainable crop production.