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Categories: Biology: Genetics, Space: Structures and Features
Published How an emerging disease in dogs is shedding light on cystic fibrosis
(via sciencedaily.com) Original source A canine gallbladder disease that involves the accumulation of abnormal mucus similar to that seen in human cystic fibrosis (CF) patients is caused by improper expression of the gene associated with CF in humans. The finding could have implications for human CF patients as well as for animal models of CF.
Published Dark matter: A camera trap for the invisible
(via sciencedaily.com) Original source AI-powered image recognition could give researchers a new tool in hunt for dark matter.
Published From genes to jeans: New genetic insights may lead to drought resilient cotton
(via sciencedaily.com) Original source Cotton is woven into the very fabric of our lives, from soft T-shirts to comfortable jeans and cozy bedsheets. It's the world's leading renewable textile fiber and the backbone of a global industry worth billions. As climate change intensifies, cotton farmers face increasing challenges from drought and heat. However, new research offers hope for developing more resilient varieties that can maintain high yields even under water-stressed conditions.
Published New progress in research into malignant catarrhal fever in cattle
(via sciencedaily.com) Original source A research team has published a groundbreaking study on malignant catarrhal fever (MCF). This disease is caused by the alcelaphine gammaherpesvirus 1 (AlHV-1), which infects its natural host, the wildebeest. This study sheds light on the mechanisms by which this virus, which is asymptomatic and latent in the wildebeest, causes an oligoclonal expansion of CD8+ T lymphocytes in cattle, leading to the development of MCF.
Published Researchers decipher new molecular mechanisms related to biological tissue regeneration
(via sciencedaily.com) Original source A study opens new perspectives to better understand how the molecular mechanisms involved in regenerative medicine work. The study focuses on tumor necrosis factor- (TNF- ) and its receptors TNFR, molecules of key interest in biomedicine due to their involvement in multiple diseases such as obesity related to type 2 diabetes mellitus, inflammatory bowel disease and several types of cancer.
Published Lampreys possess a 'jaw-dropping' evolutionary origin
(via sciencedaily.com) Original source Lampreys are one of only two living jawless vertebrates Jaws are formed by a key stem cell population called the neural crest New research reveals the gene regulatory changes that may explain morphological differences between jawed and jawless vertebrates.
Published New drug shows promise in clearing HIV from brain
(via sciencedaily.com) Original source An experimental drug originally developed to treat cancer may help clear HIV from infected cells in the brain, according to a new study. By targeting infected cells in the brain, drug may clear virus from hidden areas that have been a major challenge in HIV treatment.
Published NASA's Fermi finds new feature in brightest gamma-ray burst yet seen
(via sciencedaily.com) Original source In October 2022, astronomers were stunned by what was quickly dubbed the BOAT -- the brightest-of-all-time gamma-ray burst (GRB). Now an international science team reports that data from NASA's Fermi Gamma-ray Space Telescope reveals a feature never seen before.
Published Dark matter flies ahead of normal matter in mega galaxy cluster collision
(via sciencedaily.com) Original source Astronomers have untangled a messy collision between two massive clusters of galaxies in which the clusters' vast clouds of dark matter have decoupled from the so-called normal matter.
Published Researchers are closing in on a mouse model for late-onset Alzheimer's
(via sciencedaily.com) Original source Researchers are working to create the first strain of mice that's genetically susceptible to late-onset Alzheimer's, with potentially transformative implications for dementia research.
Published Research sheds light on the role of PTPRK in tissue repair and cancer
(via sciencedaily.com) Original source New research has advanced our knowledge of multiple roles for PTPRK, a receptor tyrosine phosphatase linked to the regulation of cell-cell adhesion, growth factor signalling and tumor suppression. Through a characterization of the function of PTPRK in human cell lines and mice, the team distinguished catalytic and non-catalytic functions of PTPRK. The findings extend what is known about the signalling mechanisms involving PTPRK as a phosphatase and its role in colorectal health but also shed new light on the extent of its function via non-catalytic signalling mechanisms.
Published Images of nearest 'super-Jupiter' open a new window to exoplanet research
(via sciencedaily.com) Original source Using the James Webb Space Telescope (JWST), astronomers imaged a new exoplanet that orbits a star in the nearby triple system Epsilon Indi. The planet is a cold super-Jupiter exhibiting a temperature of around 0 degrees Celsius and a wide orbit comparable to that of Neptune around the Sun. This measurement was only possible thanks to JWST's unprecedented imaging capabilities in the thermal infrared. It exemplifies the potential of finding many more such planets similar to Jupiter in mass, temperature, and orbit. Studying them will improve our knowledge of how gas giants form and evolve in time.
Published Under pressure: How cells respond to physical stress
(via sciencedaily.com) Original source Cell membranes play a crucial role in maintaining the integrity and functionality of cells. However, the mechanisms by which they perform these roles are not yet fully understood. Scientists have used cryo-electron microscopy to observe how lipids and proteins at the plasma membrane interact and react to mechanical stress. This work shows that, depending on conditions, small membrane regions can stabilize various lipids to trigger specific cellular responses. These discoveries confirm the existence of well-organized lipid domains and begin to reveal the role they play in cell survival.
Published Dual action antibiotic could make bacterial resistance nearly impossible
(via sciencedaily.com) Original source New drug that disrupts two cellular targets would make it much harder for bacteria to evolve resistance.
Published New rapid method for determining virus infectivity
(via sciencedaily.com) Original source A new method that can rapidly determine whether a virus is infectious or non-infectious could revolutionize the response to future pandemics, researchers report.
Published Fruit fly post-mating behavior controlled by male-derived peptide via command neurons, study finds
(via sciencedaily.com) Original source Scientists have succeeded in pinpointing the neurons within a female fruit fly's brain that respond to signals from the male during mating.
Published Researchers explore the effects of stellar magnetism on potential habitability of exoplanets
(via sciencedaily.com) Original source A study extends the definition of a habitable zone for planets to include their star's magnetic field.
Published Astrophysicists uncover supermassive blackhole/dark matter connection in solving the 'final parsec problem'
(via sciencedaily.com) Original source Researchers have found a link between some of the largest and smallest objects in the cosmos: supermassive black holes and dark matter particles. Their new calculations reveal that pairs of supermassive black holes (SMBHs) can merge into a single larger black hole because of previously overlooked behavior of dark matter particles, proposing a solution to the longstanding 'final parsec problem' in astronomy.
Published New genetic test will eliminate a form of inherited blindness in dogs
(via sciencedaily.com) Original source Scientists have identified the genetic mutation that causes progressive retinal atrophy in English Shepherd Dogs, which results in incurable blindness, and developed a genetic test to help eliminate the disease from future generations of the breed.
Published Exposing dengue's invasion strategies
(via sciencedaily.com) Original source Mosquito-borne viral infections once confined to tropical regions are spreading. Dengue virus infects up to 400 million people worldwide each year according to World Health Organization estimates, and no available treatments exist for this disease. Now, research uncovered surprising strategies for how dengue and hundreds of other viruses replicate in their hosts, with the potential to aid in developing novel antiviral treatments and vaccines.