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Categories: Biology: Molecular, Space: Structures and Features
Published Gut bacteria can process dietary fiber into an anti-allergy weapon



Short-chain fatty acids (SCFAs), which are produced by gut bacteria from dietary fiber, regulate our immune system, but the mechanism of their action remains unknown. In a recent study, researchers investigated how SCFAs interact with mast cells, a type of white blood cell that plays a central role in allergic reactions. Their findings and insights could lead to innovative and effective anti-allergy medications, supplements, and diets, paving the way for healthier lives.
Published Shining a new light on the tug-of-war between virus and host



The interplay between ribonucleic acid (RNA) and proteins is not only important for maintaining cellular homeostasis but is also at the center of the tug-of-war between virus and host. Until now, there has been no method to globally map direct interactions of individual RNA regions in an unbiased fashion without the need for genetic modification of the target RNA or cell. Researchers have now developed a breakthrough tool that overcomes this limitation.
Published Bright galaxies put dark matter to the test



The earliest galaxies are thought to have formed as the gravitational pull of dark matter, which has been impossible to study directly, slowly drew in enough hydrogen and helium to ignite stars. But astrophysicists now show that after the Big Bang, hydrogen and helium gas bounced at supersonic speeds off dense, slowly moving clumps of cold dark matter. When the gas fell back in millennia later, stars formed all at once, creating small, exceptionally bright galaxies. If models of cold dark matter are correct, the James Webb Space Telescope should be able to find patches of bright galaxies in the early universe, potentially offering the first effective test for theories about dark matter. If it doesn't, scientists have to go back to the drawing board with dark matter.
Published How seahorse-like toxins kill insects



Insect-killing bacteria typically release toxins to slay their hosts. The bacterium Photorhabdus luminescens, for example, pumps insect larvae full of the lethal 'Makes caterpillars floppy 1' (Mcf1) toxin, leading them to first become droopy and then dead. However, it has so far been a mystery how Mcf1 unfolds its devastating effect. Researchers successfully used cryo-electron microscopy (cryo-EM) and biochemical assays to characterize the first-ever Mcf1 structure, allowing them to propose a molecular mechanism of the toxin's action. Understanding how bacterial toxins perform their deadly task in such detail is very useful for engineering novel biopesticides, thereby reducing the use of barely specific chemical agents with harmful side effects for the ecosystem.
Published Using computers to design proteins allows researchers to make tunable hydrogels that can form both inside and outside of cells



New research demonstrates a new class of hydrogels that can form not just outside cells, but also inside of them. These hydrogels exhibited similar mechanical properties both inside and outside of cells, providing researchers with a new tool to group proteins together inside of cells.
Published DNA particles that mimic viruses hold promise as vaccines



Using a DNA-based delivery particle, researchers created a vaccine that can induce a strong antibody response against SARS-CoV-2.
Published Asparagus and orchids are more similar than you think



How is a beech leaf constructed? What determines the appearance of an asparagus? A new 'encyclopaedia' helps us learn more about the building blocks of plants. The encyclopaedia, probably the largest of its kind, could be used to improve targeted plant breeding efforts, to make them both more climate-resilient and more easily digestible.
Published 'Genomic time machine' reveals secrets of our DNA



Researchers reveal a novel method to uncover bits of our genetic blueprint that come from ancient genetic parasites, offering fresh insights into human evolution and health.
Published Staggering structure in 19 nearby spiral galaxies



The James Webb Space Telescope observed 19 nearby face-on spiral galaxies in near- and mid-infrared light as part of its contributions to the Physics at High Angular resolution in Nearby GalaxieS (PHANGS) program.
Published A non-allergenic wheat protein for growing better cultivated meat



As the world's population increases, cultivated or lab-grown meat -- animal muscle and fat cells grown in laboratory conditions -- has emerged as a potential way to satisfy future protein needs. And edible, inexpensive plant proteins could be used to grow these cell cultures. Now, researchers report that the non-allergenic wheat protein glutenin successfully grew striated muscle layers and flat fat layers, which could be combined to produce meat-like textures.
Published Researchers spying for signs of life among exoplanet atmospheres



The next generation of advanced telescopes could sharpen the hunt for potential extraterrestrial life by closely scrutinizing the atmospheres of nearby exoplanets, new research suggests.
Published Astronomers spot 18 black holes gobbling up nearby stars



Scientists have identified 18 new tidal disruption events (TDEs) -- extreme instances when a nearby star is tidally drawn into a black hole and ripped to shreds. The detections more than double the number of known TDEs in the nearby universe.
Published How obesity dismantles our mitochondria



Researchers found that when mice were fed a high-fat diet, mitochondria within their fat cells broke apart and were less able to burn fat, leading to weight gain. They also found they could reverse the effect by targeting a single gene, suggesting a new treatment strategy for obesity.
Published Astronomers unravel mysteries of planet formation and evolution in distant planetary system



TOI-1136, a dwarf star located more than 270 light years from Earth, is host to six confirmed exoplanets and a seventh as yet unconfirmed candidate. The system has provided a rich source of information on planet formation and evolution in a young solar system. Researchers used a variety of tools to compile radial velocity and transit timing variation readings to derive highly precise measurements of the exoplants' masses, orbital information and atmospheres.
Published Soap bark discovery offers a sustainability booster for the global vaccine market



A valuable molecule sourced from the soapbark tree and used as a key ingredient in vaccines, has been replicated in an alternative plant host for the first time, opening unprecedented opportunities for the vaccine industry.
Published Stars travel more slowly at Milky Way's edge



Physicists discovered stars near the edge of the Milky Way travel more slowly than those closer to its center -- a surprise suggesting our galaxy's gravitational core may have less dark matter than previously thought.
Published 'Old smokers' and 'squalling newborns' among hidden stars spotted for first time



'Hidden' stars including a new type of elderly giant nicknamed an 'old smoker' have been spotted for the first time by astronomers. The mystery objects exist at the heart of our Milky Way galaxy and can sit quietly for decades -- fading almost to invisibility -- before suddenly puffing out clouds of smoke, according to a new study.
Published How HIV smuggles its genetic material into the cell nucleus



Around one million individuals worldwide become infected with HIV, the virus that causes AIDS, each year. To replicate and spread the infection, the virus must smuggle its genetic material into the cell nucleus and integrate it into a chromosome. Research teams have now discovered that its capsid has evolved into a molecular transporter. As such, it can directly breach a crucial barrier, which normally protects the cell nucleus against viral invaders. This way of smuggling keeps the viral genome invisible to anti-viral sensors in the cytoplasm.
Published How macrophages regulate regenerative healing in spiny mice



A team of researchers is delving deeper into the science behind how spiny mice can regenerate lost tissue and using what they learn to trigger regeneration in other types of mice -- advances which one day may be translated into humans. Whereas adult laboratory mice heal injuries with scar tissue, spiny mice have the unique ability to regrow lost skin and regenerate musculoskeletal tissues in their body.
Published Faint features in galaxy NGC 5728 revealed



A new study describes the best method to improve images obtained by the James Webb Science Telescope (JWST) using a mathematical approach called deconvolution.