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Categories: Chemistry: Organic Chemistry, Engineering: Nanotechnology
Published Sugar-based catalyst upcycles carbon dioxide
(via sciencedaily.com) Original source New catalyst is made from an inexpensive, abundant metal and table sugar. Catalyst converts carbon dioxide (CO2) into carbon monoxide, a building block for producing a variety of useful chemicals including syngas. With recent advances in carbon capture technologies, post-combustion carbon capture is becoming a plausible option to help tackle the global climate change crisis. But how to handle the captured carbon remains an open-ended question. The new catalyst potentially could provide one solution for disposing the potent greenhouse gas by converting it into a more valuable product.
Published New approach in the synthesis of complex natural substances
(via sciencedaily.com) Original source Many natural substances possess interesting characteristics, and can form the basis of new active compounds in medicine. Terpenes, for example, are a group of substances, some of which are already used in therapies against cancer, malaria or epilepsy. They are found as fragrances in cosmetics or as flavorings in food, and form the basis of new medications: Terpenes are natural substances that occur in plants, insects and sea sponges. They are difficult to produce synthetically. However, chemists are now introducing a new method of synthesis.
Published Researchers create new chemical compound to solve 120-year-old problem
(via sciencedaily.com) Original source Chemists have created a highly reactive chemical compound that has eluded scientists for more than 120 years. The discovery could lead to new drug treatments, safer agricultural products, and better electronics.
Published Activity in a room stirs up nanoparticles left over from consumer sprays
(via sciencedaily.com) Original source Common household products containing nanoparticles -- grains of engineered material so miniscule they are invisible to the eye -- could be contributing to a new form of indoor air pollution, according to a new study.
Published Scientists solve chemical mystery at the interface of biology and technology
(via sciencedaily.com) Original source Organic electrochemical transistors (OECTs) allow current to flow in devices like implantable biosensors. But scientists long knew about a quirk of OECTs that no one could explain: When an OECT is switched on, there is a lag before current reaches the desired operational level. When switched off, there is no lag. Current drops immediately. Researchers report that they have discovered the reason for this activation lag, and in the process are paving the way to custom-tailored OECTs for a growing list of applications in biosensing, brain-inspired computation and beyond.
Published Research on RNA editing illuminates possible lifesaving treatments for genetic diseases
(via sciencedaily.com) Original source The research explores how CRISPR can be used to edit RNA.
Published When does a conductor not conduct?
(via sciencedaily.com) Original source A new study uncovers a switchable, atomically-thin metal-organic material that could be used in future low-energy electronic technologies. The study shows that electron interactions in this material create an unusual electrically-insulating phase in which electrons are 'frozen'. By reducing the population of electrons, the authors are able to unfreeze the remaining electrons, allowing for controlled transitions between insulating and electrically-conductive phases: the key to the on-off binary operations of classical computing.
Published Speeding up spectroscopic analysis
(via sciencedaily.com) Original source Ultrafast laser spectroscopy allows the ascertainment of dynamics over extremely short time scales, making it a very useful tool in many scientific and industrial applications. A major disadvantage is the considerable measuring time this technique usually requires, which often leads to lengthy acquisition times spanning minutes to hours. Researchers have now developed a technique to speed up spectroscopic analysis.
Published Imaging technique shows new details of peptide structures
(via sciencedaily.com) Original source Researchers outline how they used a chemical probe to light up interlocking peptides. Their technique will help scientists differentiate synthetic peptides from toxic types found in Alzheimer's disease.
Published Getting dynamic information from static snapshots
(via sciencedaily.com) Original source Researchers have created TopicVelo, a powerful new method of using the static snapshots from scRNA-seq to study how cells and genes change over time. This will help researchers better study how embryos develop, cells differentiate, cancers form, and the immune system reacts.
Published A shortcut for drug discovery
(via sciencedaily.com) Original source For most human proteins, there are no small molecules known to bind them chemically (so called 'ligands'). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel medicines. Researchers at CeMM, in a collaboration with Pfizer, have now leveraged and scaled a method to measure the binding activity of hundreds of small molecules against thousands of human proteins. This large-scale study revealed tens of thousands of ligand-protein interactions that can now be explored for the development of chemical tools and therapeutics. Moreover, powered by machine learning and artificial intelligence, it allows unbiased predictions of how small molecules interact with all proteins present in living human cells. These groundbreaking results have been published in the journal Science (DOI: 10.1126/science.adk5864), and all generated data and models are freely available for the scientific community.
Published Nanomaterial that mimics proteins could be basis for new neurodegenerative disease treatments
(via sciencedaily.com) Original source A newly developed nanomaterial that mimics the behavior of proteins could be an effective tool for treating Alzheimer's and other neurodegenerative diseases. The nanomaterial alters the interaction between two key proteins in brain cells -- with a potentially powerful therapeutic effect.
Published The longer spilled oil lingers in freshwater, the more persistent compounds it produces
(via sciencedaily.com) Original source Oil is an important natural resource for many industries, but it can lead to serious environmental damage when accidentally spilled. While large oil spills are highly publicized, every year there are many smaller-scale spills into lakes, rivers and oceans. The longer that oil remains in freshwater, the more chemical changes it undergoes, creating products that can persist in the environment.
Published Diamond dust shines bright in Magnetic Resonance Imaging
(via sciencedaily.com) Original source An unexpected discovery surprised a scientist: nanometer-sized diamond particles, which were intended for a completely different purpose, shone brightly in a magnetic resonance imaging experiment -- much brighter than the actual contrast agent, the heavy metal gadolinium. Could diamond dust -- in addition to its use in drug delivery to treat tumor cells -- one day become a novel contrast agent used for MRI?
Published 'Like a nanoscopic Moon lander': Scientists unlock secret of how pyramidal molecules move across surfaces
(via sciencedaily.com) Original source Scientists have watched a molecule move across a graphite surface in unprecedented detail. It turns out this particular molecule moves like a Moon lander -- and the insights hold potential for future nanotechnologies.
Published The secret to saving old books could be gluten-free glues
(via sciencedaily.com) Original source 'Bookworm' is a cute thing to call a voracious reader, but actual bookworms -- as well as microorganisms and time -- break down the flour pastes commonly used to keep old publications in one piece. Now, researchers have analyzed the proteins in wheat-based glues applied in historic bookbinding to provide insights on their adhesiveness and how they degrade. This information could help conservators restore and preserve treasured tomes for future generations.
Published Pattern formation in the nano-cosmos
(via sciencedaily.com) Original source A new model extends the theory of elastic phase separation towards nanoscopic structures. Such patterns are frequent in biological systems and also used in nano-engineering to create structural color. With their new insights, the scientists can predict the length scale of nanoscopic patterns and thus control them during production.
Published Biophysics: Testing how well biomarkers work
(via sciencedaily.com) Original source Researchers have developed a method to determine how reliably target proteins can be labeled using super-resolution fluorescence microscopy.
Published A chemical mystery solved -- the reaction explaining large carbon sinks
(via sciencedaily.com) Original source A mystery that has puzzled the scientific community for over 50 years has finally been solved. A team has discovered that a certain type of chemical reaction can explain why organic matter found in rivers and lakes is so resistant to degradation.
Published Researchers create artificial cells that act like living cells
(via sciencedaily.com) Original source Researchers describe the steps they took to manipulate DNA and proteins -- essential building blocks of life -- to create cells that look and act like cells from the body. This accomplishment, a first in the field, has implications for efforts in regenerative medicine, drug delivery systems and diagnostic tools.