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Categories: Chemistry: Organic Chemistry, Engineering: Nanotechnology

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Researchers uncovered the role of the third intracellular loop in the G protein-coupled receptors' signaling mechanism, which could lead to a more targeted approach to drug discovery and a paradigm shift for new therapeutics.

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A new process that lets scientists chemically cut apart and stitch together nanoscopic layers of two-dimensional materials -- like a tailor altering a suit -- could be just the tool for designing the technology of a sustainable energy future. Researchers have developed a method for structurally splitting, editing and reconstituting layered materials, called MAX phases and MXenes, with the potential of producing new materials with very unusual compositions and exceptional properties.

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In organic solar cells, carbon-based polymers convert light into charges that are passed to an acceptor. Scientists have now calculated how this happens by combining molecular dynamics simulations with quantum calculations and have provided theoretical insights to interpret experimental data.

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Pushing the MINFLUX technique to higher spatial and temporal precision allows protein dynamics to be observed under physiological conditions.

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Proteins are the heavy-lifters of biochemistry. These beefy molecules act as building blocks, receptors, processors, couriers and catalysts. Naturally, scientists have devoted a lot of research to understanding and manipulating proteins.

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Micron-sized 'bow ties,' self-assembled from nanoparticles, form a variety of different curling shapes that can be precisely controlled, a research team has shown.

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Breaking a longstanding impasse in our understanding of olfaction, scientists have created the first molecular-level, 3D picture of how an odor molecule activates a human odorant receptor, a crucial step in deciphering the sense of smell.

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Despite recent advancements, many highly sensitive diagnostic tests for viral diseases still require complicated techniques to prepare a sample or interpret a result, making them impractical for point-of-care settings or areas with few resources. But now, a team has developed a sensitive method that analyzes viral nucleic acids in as little as 20 minutes and can be completed in one step with 'glow-in-the-dark' proteins.

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Researchers have engineered a material with the potential to dramatically cut the amount of heat power plants release into the atmosphere.

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Scientists have transformed single-cell algae into functional perovskite materials. The team has converted mineral shells of algae into lead halide perovskites with tunable physical properties. The new perovskites have unique nano-architectures unachievable by conventional synthetic production. The method can be applied to the mass production of perovskites with tunable structural and electro-optical properties from single-celled organisms.

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A 'best practice' protocol for researchers developing piezoelectric materials has been developed by scientists. The protocol was developed by an international team led by physicists in response to findings that experimental reports lack consistency. The researchers made the shocking discovery that nine out of 10 scientific papers miss experimental information that is crucial to ensure the reproducibility of the reported work.

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Researchers have pioneered a technique to observe the 3D internal structure of rechargeable batteries. This opens up a wide range of areas for the new technique from energy storage and chemical engineering to biomedical applications.

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Metal organic frameworks, or MOFs, are kind of like plastic building block toys. The pieces are simple to connect, yet they're capable of building highly sophisticated structures.

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A team of scientists dedicated to pinpointing the primordial origins of metabolism -- a set of core chemical reactions that first powered life on Earth -- has identified part of a protein that could provide scientists clues to detecting planets on the verge of producing life.

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A newly developed molecular catalyst specifically tailored for mechanochemical reaction conditions enables high-efficiency transformations at near room temperature.

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Fluorescence is a fascinating natural phenomenon. It is based on the fact that certain materials can absorb light of a certain wavelength and then emit light of a different wavelength. Fluorescent materials play an important role in our everyday lives, for example in modern screens. Due to the high demand for applications, science is constantly striving to produce new and easily accessible molecules with high fluorescence efficiency.

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Researchers have developed a super-resolution microscopy method for the rapid differentiation of molecular structures in 3D.

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Researchers have developed and demonstrated an efficient and scalable technique that allows them to manufacture soft polymer materials in a dozen different structures, or 'morphologies,' from ribbons and nanoscale sheets to rods and branched particles. The technique allows users to finely tune the morphology of the materials at the micro- and nano-scale.

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A micro-architected material made from tiny knots proves tougher and more durable than unknotted counterparts.

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A new biosensor offers scientists the first dynamic glimpses of manganese, an elusive metal ion that is essential for life.