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Categories: Chemistry: Biochemistry, Physics: Quantum Physics

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Researchers have developed a novel and highly efficient method for rapid antibiotic susceptibility testing using optical microscopy. The technique, called Optical Nanomotion Detection, is extremely rapid, single-cell sensitive, label-free, and requires only a basic traditional optical microscope, equipped with a camera or a mobile phone.

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Researchers have designed a tabletop-sized vaccine printer that could be scaled up to produce hundreds of vaccine doses in a day and deployed anywhere vaccines are needed. The vaccine doses are contained within microneedle patches that can be stored long-term at room temperature and applied to the skin, avoiding the need for injections.

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A team of physicists has illuminated certain properties of quantum systems by observing how their fluctuations spread over time. The research offers an intricate understanding of a complex phenomenon that is foundational to quantum computing.

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A new smart material is activated by both heat and electricity, making it the first ever to respond to two different stimuli.

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Scientists have demonstrated nanowire networks can exhibit both short- and long-term memory like the human brain.

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Hydrogen, the most abundant element in the universe, is found everywhere from the dust filling most of outer space to the cores of stars to many substances here on Earth. This would be reason enough to study hydrogen, but its individual atoms are also the simplest of any element with just one proton and one electron.

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Despite the increasing use of genomic sequencing in clinical practice, interpreting rare genetic mutations, even among well-studied disease genes, remains difficult. Current predictive models are useful for interpreting those mutations, but they are prone to misclassify those that do not cause diseases, contributing to false positives.

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A new article shows how the choice of network representation can influence the observed effects. Their work focuses on the phenomenon of synchronization, which emerges in systems from circadian clocks to vascular networks.

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Engineers developed a method to create synthetic spider silk at high yields while retaining strength and toughness using mussel foot proteins.

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An AI strategy proven adept at board games like Chess and Go, reinforcement learning, has now been adapted for a powerful protein design program. The results show that reinforcement learning can do more than master board games. When trained to solve long-standing puzzles in protein science, the software excelled at creating useful molecules. In one experiment, proteins made with the new approach were found to be more effective at generating useful antibodies in mice than were previous methods. If this method is applied to the right research problems, it likely could accelerate progress in a variety of scientific fields.

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A new machine-learning system can generate protein designs with certain structural features, and which do not exist in nature. These proteins could be utilized to make materials that have similar mechanical properties to existing materials, like polymers, but which would have a much smaller carbon footprint.

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The 'spooky action at a distance' that once unnerved Einstein may be on its way to being as pedestrian as the gyroscopes that currently measure acceleration in smartphones.

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Mechanically responsive molecular crystals are extremely useful in soft robotics, which requires a versatile actuation technology. Crystals driven by the photothermal effect are particularly promising for achieving high-speed actuation. However, the response (bending) observed in these crystals is usually small. Now, scientists address this issue by inducing large resonated natural vibrations in anisole crystals with UV light illumination at the natural vibration frequency of the crystal.

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Recently quantum computers started to work with more than just the zeros and ones we know from classical computers. Now a team demonstrates a way to efficiently create entanglement of such high-dimensional systems to enable more powerful calculations.

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There are high expectations that quantum computers may deliver revolutionary new possibilities for simulating chemical processes. This could have a major impact on everything from the development of new pharmaceuticals to new materials. Researchers have now used a quantum computer to undertake calculations within a real-life case in chemistry.

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In the future, communications networks and computers will use information stored in objects governed by the microscopic laws of quantum mechanics. This capability can potentially underpin communication with greatly enhanced security and computers with unprecedented power. A vital component of these technologies will be memory devices capable of storing quantum information to be retrieved at will.

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Researchers find that when immunostimulatory drugs called imidazoquinolines are delivered using specialized bottlebrush nanoparticles, the drugs provoke the immune system to attack tumors while eliminating the side effects that occur when the drugs are given on their own.

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In the quantum world particles can instantaneously know about each other's state, even when separated by large distances. This is known as nonlocality. Now, A research group has produced some interesting findings on the Hardy nonlocality that have important ramifications for understanding quantum mechanics and its potential applications in communications.

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Small interfering RNAs (siRNAs) are novel therapeutics that can be used to treat a wide range of diseases. This has led to a growing demand for selective, efficient, and safe ways of delivering siRNA in cells. Now, in a cooperation between the Universities of Amsterdam and Leiden, researchers have developed dedicated molecular nanocages for siRNA delivery. In a paper just out in the Journal Chem they present nanocages that are easy to prepare and display tuneable siRNA delivery characteristics.

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Researchers report having achieved quantum teleportation from a photon to a solid-state qubit over a distance of 1km, with a novel approach using multiplexed quantum memories.