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Chemistry: Biochemistry Chemistry: General Engineering: Nanotechnology Offbeat: Computers and Math Offbeat: General
Published

Microrobot-packed pill shows promise for treating inflammatory bowel disease in mice      (via sciencedaily.com)     Original source 

Engineers have developed a pill that releases microscopic robots, or microrobots, into the colon to treat inflammatory bowel disease (IBD). The experimental treatment, given orally, has shown success in mice. It significantly reduced IBD symptoms and promoted the healing of damaged colon tissue without causing toxic side effects.

Chemistry: Biochemistry Chemistry: Inorganic Chemistry Engineering: Nanotechnology Physics: General Physics: Optics
Published

A new study highlights potential of ultrafast laser processing for next-gen devices      (via sciencedaily.com)     Original source 

A new study uncovers the remarkable potential of ultrafast lasers that could provide innovative solutions in 2D materials processing for many technology developers such as high-speed photodetectors, flexible electronics, biohybrids, and next-generation solar cells.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Chemistry: Biochemistry Chemistry: General Chemistry: Inorganic Chemistry Chemistry: Organic Chemistry Ecology: Sea Life Environmental: General Geoscience: Geochemistry
Published

Towards non-toxic antifouling agents: A novel method for total synthesis of scabrolide F      (via sciencedaily.com)     Original source 

Norcembranolide diterpenes, isolated from the soft corals of the genus Sinularia, are important compounds for the development of new drugs, owing to their diverse biological activities. However, total synthesis methods for these compounds are scarce. Now, a team of researchers has achieved the total synthesis of scabrolide F, a norcembranolide diterpene. They also revealed its non-toxic antifouling properties. This novel method can lead to the development of new drugs and antifouling agents.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular Chemistry: Biochemistry Engineering: Nanotechnology
Published

Revealing the dynamic choreography inside multilayer vesicles      (via sciencedaily.com)     Original source 

Our cells and the machinery inside them are engaged in a constant dance. This dance involves some surprisingly complicated choreography within the lipid bilayers that comprise cell membranes and vesicles -- structures that transport waste or food within cells. In a recent paper, researchers shed some light on how these vesicles self-assemble, knowledge that could help scientists design bio-inspired vesicles for drug-delivery or inspire them to create life-like synthetic materials.

Biology: Biochemistry Biology: General Biology: Microbiology Chemistry: Biochemistry Physics: Optics
Published

Light-weight microscope captures large-scale brain activity of mice on the move      (via sciencedaily.com)     Original source 

With a new microscope that's as light as a penny, researchers can now observe broad swaths of the brain in action as mice move about and interact with their environments.

Chemistry: Biochemistry Environmental: Wildfires
Published

Wildfires increasingly threaten oil and gas drill sites, compounding potential health risks      (via sciencedaily.com)     Original source 

More than 100,000 oil and gas wells across the western U.S. are in areas burned by wildfires in recent decades, a new study has found, and some 3 million people live next to wells that in the future could be in the path of fires worsened by climate change.

Chemistry: Biochemistry Computer Science: Artificial Intelligence (AI) Engineering: Robotics Research Offbeat: Computers and Math Offbeat: General
Published

Robots face the future      (via sciencedaily.com)     Original source 

Researchers have found a way to bind engineered skin tissue to the complex forms of humanoid robots. This brings with it potential benefits to robotic platforms such as increased mobility, self-healing abilities, embedded sensing capabilities and an increasingly lifelike appearance. Taking inspiration from human skin ligaments, the team included special perforations in a robot face, which helped a layer of skin take hold.

Biology: Biochemistry Biology: Cell Biology Biology: Microbiology Chemistry: Biochemistry
Published

3D-printed chip sensor detects foodborne pathogens for safer products      (via sciencedaily.com)     Original source 

Researchers have developed a new method for detecting foodborne pathogens that is faster, cheaper, and more effective than existing methods. Their microfluidic chip uses light to detect multiple types of pathogens simultaneously and is created using 3D printing, making it easy to fabricate in large amounts and modify to target specific pathogens. The researchers hope their technique can improve screening processes and keep contaminated food out of the hands of consumers.

Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

Researchers develop RNA-targeting technology for precisely manipulating parts of human genes      (via sciencedaily.com)     Original source 

Researchers have harnessed a bacterial immune defense system, known as CRISPR, to efficiently and precisely control the process of RNA splicing. The technology opens the door to new applications, including systematically interrogating the functions of parts of genes and correcting splicing deficiencies that underlie numerous diseases and disorders.

Chemistry: Biochemistry Computer Science: General Energy: Technology
Published

Researchers engineer AI path to prevent power outages      (via sciencedaily.com)     Original source 

Researchers developed an artificial intelligence (AI) model that could help electrical grids prevent power outages by automatically rerouting electricity in milliseconds. The approach is an early example of 'self-healing grid' technology, which uses AI to detect and repair problems such as outages autonomously and without human intervention when issues occur, such as storm-damaged power lines.

Chemistry: Biochemistry Computer Science: Artificial Intelligence (AI) Computer Science: Virtual Reality (VR) Mathematics: Modeling Offbeat: Computers and Math Offbeat: General
Published

Prying open the AI black box      (via sciencedaily.com)     Original source 

Meet SQUID, a new computational tool. Compared with other genomic AI models, SQUID is more consistent, reduces background noise, and can yield better predictions regarding critical mutations. The new system aims to bring scientists closer to their findings' true medical implications.

Chemistry: Biochemistry Physics: General Physics: Optics
Published

Controlling electronics with light: The magnetite breakthrough      (via sciencedaily.com)     Original source 

Researchers have discovered that by shining different wavelengths (colors) of light on a material called magnetite, they can change its state, e.g. making it more or less conducive to electricity. The discovery could lead to new ways of designing new materials for electronics such as memory storage, sensors, and other devices that rely on fast and efficient material responses.

Chemistry: Biochemistry Chemistry: General Chemistry: Organic Chemistry
Published

Membrane protein analogues could accelerate drug discovery      (via sciencedaily.com)     Original source 

Researchers have created a deep learning pipeline for designing soluble analogues of key protein structures used in pharmaceutical development, sidestepping the prohibitive cost of extracting these proteins from cell membranes.

Chemistry: Biochemistry
Published

Lab-grown muscles reveal mysteries of rare muscle diseases      (via sciencedaily.com)     Original source 

Biomedical engineers have grown muscles in a lab to better understand and test treatments for a group of extremely rare muscle disorders called dysferlinopathy or limb girdle muscular dystrophies 2B (LGMD2B). The research revealed the biological mechanisms underlying the disease and showed that a combination of existing treatments could alleviate its symptoms.

Chemistry: Biochemistry
Published

Scientists discover new behavior of membranes that could lead to unprecedented separations      (via sciencedaily.com)     Original source 

Argonne scientists have used isoporous membranes -- membranes with pores of equal size and shape -- and recirculation to create separations at the nanoscale that overcome previous limitations.

Chemistry: Biochemistry Chemistry: General
Published

Scientists devise algorithm to engineer improved enzymes      (via sciencedaily.com)     Original source 

Scientists have prototyped a new method for 'rationally engineering' enzymes to deliver improved performance. They have devised an algorithm, which takes into account an enzyme's evolutionary history, to flag where mutations could be introduced with a high likelihood of delivering functional improvements. Their work could have significant, wide-ranging impacts across a suite of industries, from food production to human health.

Chemistry: Biochemistry
Published

Creation of a power-generating, gel electret-based device      (via sciencedaily.com)     Original source 

A team of researchers has developed a gel electret capable of stably retaining a large electrostatic charge. The team then combined this gel with highly flexible electrodes to create a sensor capable of perceiving low-frequency vibrations (e.g., vibrations generated by human motion) and converting them into output voltage signals. This device may potentially be used as a wearable healthcare sensor.

Chemistry: Biochemistry
Published

Transforming inexpensive quinolines into complex drug candidates      (via sciencedaily.com)     Original source 

An innovative synthesis strategy opened up the way to 2D/3D fused frameworks using inexpensive quinolines as feedstock, report scientists. By leveraging a light-sensitive borate intermediate, the scientists could transform quinoline derivatives into a great variety of 2D/3D fused frameworks in a straightforward and cost-effective manner. Their findings are expected to enable the synthesis of highly customizable drug candidates.