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Categories: Chemistry: Organic Chemistry, Computer Science: General

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Aptamers, nucleic acids capable of selectively binding to viruses, proteins, ions, small molecules, and various other targets, are garnering attention in drug development as potential antibody substitutes for their thermal and chemical stability as well as ability to inhibit specific enzymes or target proteins through three-dimensional binding. They also hold promise for swift diagnoses of colon cancer and other challenging diseases by targeting elusive biomarkers. Despite their utility, these aptamers are susceptible to easy degradation by multiple enzymes, presenting a significant challenge.

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A research team has achieved a significant breakthrough in the field of organic semiconductors. Their successful synthesis and characterization of a novel molecule called 'BNBN anthracene' has opened up new possibilities for the development of advanced electronic devices.

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Researchers have discovered that molecules experience non-reciprocal interactions without external forces. Fundamental forces such as gravity and electromagnetism are reciprocal, where two objects are attracted to each other or are repelled by each other. In our everyday experience, however, interactions don t seem to follow this reciprocal law.

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Researchers have developed a solid electrolyte for transporting hydride ions at room temperature. This breakthrough means that the full advantages of hydrogen-based solid-state batteries and fuel cells can be had without the need for constant hydration. This will reduce their complexity and cost, which is essential for advancing towards a practical hydrogen-based energy economy.

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Engineers developed a technology that delivers centimeter-level accuracy for real-time tracking in extended reality (XR) applications. It uses wireless signals to ensure precise asset localization and smooth tracking, promising to enhance virtual gaming experiences and workplace safety.

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Lights could soon use the full color suite of perfectly efficient organic light-emitting diodes, or OLEDs, that last tens of thousands of hours. The new phosphorescent OLEDs, commonly referred to as PHOLEDs, can maintain 90% of the blue light intensity for 10-14 times longer than other designs that emit similar deep blue colors. That kind of lifespan could finally make blue PHOLEDs hardy enough to be commercially viable in lights that meet the Department of Energy's 50,000-hour lifetime target. Without a stable blue PHOLED, OLED lights need to use less-efficient technology to create white light.

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Researchers develop transistor that simultaneously processes and stores information like the human brain. Transistor goes beyond categorization tasks to perform associative learning. Transistor identified similar patterns, even when given imperfect input. Previous similar devices could only operate at cryogenic temperatures; new transistor operates at room temperature, making it more practical.

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An artificial intelligence-driven system has autonomously learned about certain Nobel Prize-winning chemical reactions and designed a successful laboratory procedure to make them. The AI did so in just a few minutes and correctly on its first attempt. According to the authors, this is the first time that a non-organic intelligence planned, designed and executed this complex reaction that was invented by humans.

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In a recent study, researchers systematically tested an early version of ChatGPT's understanding of statements in six categories: facts, conspiracies, controversies, misconceptions, stereotypes, and fiction. 

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Scientists have developed a method to extract the spectral density for molecules in solvent using simple resonance Raman experiments -- a method that captures the full complexity of chemical environments.

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A research team has unveiled a remarkable breakthrough in the form of a two-dimensional (2D) Metal Organic Framework (MOF) that showcases unprecedented origami-like movement at the molecular level. This pioneering study represents a significant leap forward in the field of dynamic materials, while also hinting at futuristic applications in metamaterials and quantum computing.

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A new study finds that clinicians were fooled by biased AI models, even with provided explanations for how the model generated its diagnosis.

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A collaborative team of experimental and computational physical chemists has made an important discovery in the field of electrochemistry, shedding light on the movement of water molecules near metal electrodes. This research holds profound implications for the advancement of next-generation batteries utilizing aqueous electrolytes.

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Materials scientists developed a fast, low-cost, scalable method to make covalent organic frameworks (COFs), a class of crystalline polymers whose tunable molecular structure, large surface area and porosity could be useful in energy applications, semiconductor devices, sensors, filtration systems and drug delivery.

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Artificial intelligence can analyze registry data on people's residence, education, income, health and working conditions and, with high accuracy, predict life events.

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Researchers developed a way to quickly calculate the transition state structure of a chemical reaction, using machine-learning models.

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While screen time is generally known to affect sleep, new research suggests that interactive engagement, such as texting friends or playing video games, delays and reduces the time spent asleep to a greater extent than passive screen time, like watching television -- especially for teens.  

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Protein-splitting enzymes play an important role in many physiological processes. Such proteases are generally present in an inactive state, only becoming activated under certain conditions. Some are linked to diseases like infections or cancer, making it important to have methods that can selectively detect active proteases. Scientists have introduced a new class of protease-activity sensors: gold nanoparticles equipped with peptide DNA.

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Accurately counting manatee aggregations within a region is crucial yet challenging. Harnessing the power of AI, researchers are using a deep learning-based crowd counting approach to automatically count the number of manatees in a designated region, using images captured from CCTV cameras, which are readily available, as input. The pioneering study not only addresses the technical challenges of counting in complex outdoor environments but also offers potential ways to aid endangered species. 

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Researchers have made a breakthrough in diagnostic technology, inventing a 'lab on a chip' that can be 3D-printed in just 30 minutes. The chip has the potential to make on-the-spot testing widely accessible.