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Categories: Chemistry: Organic Chemistry, Computer Science: Quantum Computers

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Delivery systems in body continuously move materials between cells. Hijacking these systems allowed scientists to improve loading and delivery of therapeutic proteins. Biophysical principles could be used to enable more cost-effective loading of biological cargo into cell-derived delivery systems. Engineered molecules loaded up to 240 times more protein than other loading methods.

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Researchers grew crystals containing actinium and illuminated them with X-rays to learn how the radioactive metal binds with other elements. That information could help design better cancer treatments.

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RNA drugs are the next frontier of medicine, but manufacturing them requires an expensive and labor-intensive process that limits production and produces metric tons of toxic chemical waste. Researchers report a new, enzyme-based RNA synthesis method that can produce strands of RNA with both natural and modified nucleotides without the environmental hazards.

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Scientists have created a computer program that 'paints' the structure of molecules in the style of famous Dutch artist, Piet Mondrian. Researchers are opening eyes and minds to the beauty of molecular structure, as well as posing new questions about the form and function of the molecules themselves.

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Researchers have made significant inroads in understanding how nanoplastics and per- and polyfluoroalkyl substances (PFAS) -- commonly known as forever chemicals -- disrupt biomolecular structure and function. The work shows that the compounds can alter proteins found in human breast milk and infant formulas -- potentially causing developmental issues downstream.

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Researchers discover how proteins behave inside cells using AI, which has the potential to guide drug design.

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Researchers have achieved a significant breakthrough in quantum materials, potentially setting the stage for advancements in topological superconductivity and robust quantum computing.

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Researchers discovered a microscopic mechanism that solves in part the outstanding performance achieved by a new class of organic semiconductors known as non-fullerene acceptors (NFAs).

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Awarded the 2023 Nobel Prize in Chemistry, quantum dots have a wide variety of applications ranging from displays and LED lights to chemical reaction catalysis and bioimaging. These semiconductor nanocrystals are so small -- on the order of nanometers -- that their properties, such as color, are size dependent, and they start to exhibit quantum properties. This technology has been really well developed, but only in the visible spectrum, leaving untapped opportunities for technologies in both the ultraviolet and infrared regions of the electromagnetic spectrum.

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Is it possible to create a new class of materials from very different substances using the 'one-pot synthesis' approach? Chemists explain how they enable the synthesis of such novel materials.

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Researchers have identified hexagonal perovskite-related oxides as materials with exceptionally high proton conductivity and thermal stability. Their unique crystal structure and large number of oxygen vacancies enable full hydration and high proton diffusion, making these materials ideal candidates as electrolytes for next-generation protonic ceramic fuel cells that can operate at intermediate temperatures without degradation.

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Immobilizing small synthetic molecules inside protein crystals proves to be a promising avenue for studying intermediate compounds formed during chemical reactions, scientists report. By integrating this method with time-resolved serial femtosecond crystallography, they successfully visualized reaction dynamics and rapid structural changes occurring within reaction centers immobilized inside protein crystals. This innovative strategy holds significant potential for the intelligent design of drugs, catalysts, and functional materials.

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Engineers have created a device that can efficiently convert heat into electrical voltage at temperatures lower than that of outer space. The innovation could help overcome a significant obstacle to the advancement of quantum computing technologies, which require extremely low temperatures to function optimally.

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A team has discovered that the new organic molecule thienyl diketone exhibits high-efficiency phosphorescence, achieving a rate over ten times faster than traditional materials. This breakthrough provides new guidelines for developing rare metal-free organic phosphorescent materials, promising advancements in applications like organic EL displays, lighting, and cancer diagnostics.

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A new study offers new insights into the evolution of foldable proteins.

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Research could help drug developers improve the safety profiles of medications and reduce side effects.

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Researchers tested phononic nanomaterials designed with an automated genetic algorithm that responded to light pulses with controlled vibrations. This work may help in the development of next-generation sensors and computer devices.

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Chemists have discovered a way to use visible light to synthesize a class of compounds particularly well suited for use in pharmaceuticals. The class of compounds, called azetidines, had been previously identified as a good candidate to build therapeutic drugs, but the compounds are difficult to produce in chemical reactions. Now, a team has developed a method to produce a specific class of azetidines called monocyclic azetidines using visible light and a photocatalyst.

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The process that can convert pollution into benign by-products is called selective catalytic reduction, or SCR. Until now, it has been unclear how this reaction actually occurs, and contradictions have long existed between reaction models within the literature. Catalysis researchers used a technology called modulation excitation spectroscopy, or MES, to finally identify the correct pathway.

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To form qubit states in semiconductor materials, it requires tuning for numerous parameters. But as the number of qubits increases, the amount of parameters also increases, thereby complicating this process. Now, researchers have automated this process, overcoming a significant barrier to realizing quantum computers.