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Categories: Chemistry: Biochemistry, Mathematics: Modeling
Published AI tool creates 'synthetic' images of cells for enhanced microscopy analysis



Researchers have developed a method to use an image generation AI model to create realistic images of single cells, which are then used as 'synthetic data' to train an AI model to better carry out single-cell segmentation.
Published This alloy is kinky



Researchers have uncovered a remarkable metal alloy that won t crack at extreme temperatures due to kinking, or bending, of crystals in the alloy at the atomic level. Unlike most materials, the new alloy keeps its shape and resists cracking at both high and low temperature extremes, making it potentially suitable for demanding applications like high-efficiency aerospace engines.
Published Switching off the light to see better



Researchers used structured light and switchable fluorescent molecules to reduce the background light from the out-of-plane regions of microscope samples. This method allowed for the acquisition of images that surpassed the conventional resolution limit, and it may be useful for further study of cell clusters and other biological systems.
Published New sensing checks for 3D printed products could overhaul manufacturing sector



A sensing technology that can assess the quality of components in fields such as aerospace could transform UK industry.
Published Predicting cardiac arrhythmia 30 minutes before it happens



Atrial fibrillation is the most common cardiac arrhythmia worldwide with around 59 million people concerned in 2019. This irregular heartbeat is associated with increased risks of heart failure, dementia and stroke. It constitutes a significant burden to healthcare systems, making its early detection and treatment a major goal. Researchers have recently developed a deep-learning model capable of predicting the transition from a normal cardiac rhythm to atrial fibrillation. It gives early warnings on average 30 minutes before onset, with an accuracy of around 80%. These results pave the way for integration into wearable technologies, allowing early interventions and better patient outcomes.
Published AI weather forecasts captured Ciaran's destructive path



The study highlights the rapid progress and transformative potential of AI in weather prediction.
Published New copper-catalyzed C-H activation strategy



Inspired by what human liver enzymes can do, chemists have developed a new set of copper-catalyzed organic synthesis reactions for building and modifying pharmaceuticals and other molecules. The new reactions are expected to be widely used in drug discovery and optimization, as well as in other chemistry-based industries.
Published Light show in living cells



Observing proteins precisely within cells is extremely important for many branches of research but has been a significant technical challenge -- especially in living cells, as the required fluorescent labeling had to be individually attached to each protein. The research group has now overcome this hurdle: With a method called 'vpCells,' it is possible to label many proteins simultaneously, using five different fluorescent colors.
Published Octopus inspires new suction mechanism for robots



A new robotic suction cup which can grasp rough, curved and heavy stone, has been developed by scientists.
Published Teaching a computer to type like a human



A new typing model simulates the typing process instead of just predicting words.
Published When thoughts flow in one direction



Contrary to previous assumptions, nerve cells in the human neocortex are wired differently than in mice. The study found that human neurons communicate in one direction, while in mice, signals tend to flow in loops. This increases the efficiency and capacity of the human brain to process information. These discoveries could further the development of artificial neural networks.
Published From defects to order: Spontaneously emerging crystal arrangements in perovskite halides



A new hybrid layered perovskite featuring elusive spontaneous defect ordering has been found, report scientists. By introducing specific concentrations of thiocyanate ions into FAPbI3 (FA = formamidinium), they observed that ordered columnar defects appeared in the stacked crystalline layers, taking up one-third of the lattice space. These findings could pave the way to an innovative strategy for adjusting the properties of hybrid perovskites, leading to practical advances in optoelectronics and energy generation.
Published E-tongue can detect white wine spoilage before humans can



While the electronic tongue bears little physical resemblance to its namesake, the strand-like sensory probes of the 'e-tongue' still outperformed human senses when detecting contaminated wine in a recent study. In a recent experiment, the e-tongue identified signs of microorganisms in white wine within a week after contamination -- four weeks before a human panel noticed the change in aroma. This was also before those microbes could be grown from the wine in a petri-dish. Winemakers traditionally rely on these two methods, sniffing the wine and petri-dish testing, to identify potential wine 'faults' or spoilage.
Published Two-dimensional nanomaterial sets record for expert-defying, counter-intuitive expansion



Engineers have developed a record-setting nanomaterial which when stretched in one direction, expands perpendicular to the applied force.
Published 'Nanostitches' enable lighter and tougher composite materials



In an approach they call 'nanostitching,' engineers used carbon nanotubes to prevent cracking in multilayered composites. The advance could lead to next-generation airplanes and spacecraft.
Published New tagging method provides bioadhesive interface for marine sensors on diverse, soft, and fragile species



Tagging marine animals with sensors to track their movements and ocean conditions can provide important environmental and behavioral information. Existing techniques to attach sensors currently largely rely on invasive physical anchors, suction cups, and rigid glues. While these techniques can be effective for tracking marine animals with hard exoskeletons and large animals such as sharks, individuals can incur physiological and metabolic stress during the tagging process, which can affect the quality of data collection. A newly developed soft hydrogel-based bioadhesive interface for marine sensors, referred to as BIMS, holds promise as an effective, rapid, robust, and non-invasive method to tag and track all sorts of marine species, including soft and fragile species. The BIMS tagging, which is also simple and versatile, can help researchers better understand animal behavior while also capturing oceanographic data critical for helping to better understand some impacts of climate change and for resource management.
Published Cooler transformers could help electric grid



Simulations on the Stampede2 supercomputer of the Texas Advanced Computing Center (TACC) are helping scientists engineer solutions to overheating of grid transformers -- a critical component of the electric grid.
Published Physicists explain--and eliminate--unknown force dragging against water droplets on superhydrophobic surfaces



Researchers adapt a novel force measurement technique to uncover the previously unidentified physics at play at the thin air-film gap between water droplets and superhydrophobic surfaces.
Published Next-generation treatments hitch a ride into cancer cells



Researchers found that a new activator called L687 induces cancer cells to accept delivery of antisense oligonucleotide (ASO) drugs. These drugs can treat cancer by blocking the transfer of messages from genes that encourage cancer growth. Previous methods to deliver ASOs into cells had only limited success. This research will help accelerate the development and delivery of novel ASO cancer therapies.
Published Millions of gamers advance biomedical research



4.5 million gamers around the world have advanced medical science by helping to reconstruct microbial evolutionary histories using a minigame included inside the critically and commercially successful video game, Borderlands 3. Their playing has led to a significantly refined estimate of the relationships of microbes in the human gut. The results of this collaboration will both substantially advance our knowledge of the microbiome and improve on the AI programs that will be used to carry out this work in future.