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Categories: Chemistry: Biochemistry, Mathematics: Modeling

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Researchers have developed a new nanoparticle that can 'hitch a ride' on immune cells, or monocytes. Because of its tiny size, the particle can tag along directly into lymph nodes and help metastasis show up on MRIs where it would otherwise be too hard to detect. The process offers game-changing benefits for the early detection of cancer metastasis in the lymph nodes. While previously, metastasis could only be assessed by an increase in lymph node size; the new particles could lead to MRI contrast agents that can highlight metastatic cells in lymph nodes that may otherwise appear normal.

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Researchers are further improving CRISPR's versatility to engineer new grasses and yeasts for biochemical production.

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Researchers have used equipment originally intended for astronomy observation to capture transformations in the nuclear structure of atomic nuclei, reports a new study.

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The properties of supramolecular polymers are dictated by the self-assembled state of the molecules. However, not much is known about the impact of morphologies on the properties of nano- and mesoscopic-scale polymeric assemblies. Recently, a research team demonstrated how terminus-free toroids and random coils derived from the same luminescent molecule show different photophysical properties. The team also presented a novel method for purifying the toroidal structure.

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Chiral skyrmions are a special type of spin textures in magnetic materials with asymmetric exchange interactions. They can be treated as quasi-particles and carry integer topological charges. Scientists have recently studied the random walk-behaviors of chiral skyrmions by simulating their dynamics within a ferromagnetic layer surrounded by chiral flower-like obstacles. The simulations reveal that the system behaves like a topological sorting device, indicating its use in information processing and computing devices.

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A team of scientists have demonstrated the first successful use of a neural prosthetic device to recall specific memories.

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You can mend a broken heart this valentine s day now that researchers invented a new hydrogel that can be used to heal damaged heart tissue and improve cancer treatments.

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Fossils of a marine animal that lived 500 million years ago, combined with computer simulations, informed the design of a new soft robot.

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Scientists have discovered that a known practice in information technology can also be applied to chemistry. Researchers found that to enhance the sampling in chemical simulations, all you need to do is stop and restart.

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Engineers have studied how insects navigate, for the purpose of developing energy-efficient robots.

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In an image, estimating the distance between objects and the camera by using the blur in the images as clue, also known as depth from focus/defocus, is essential in computer vision. However, model-based methods fail when texture-less surfaces are present, and learning-based methods require the same camera settings during training and testing. Now, researchers have come up with an innovative strategy for depth estimation that combines the best of both the worlds to solve these limitations, extending the applicability of depth from focus/defocus.

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A coating that can hide objects in plain sight, or an implant that behaves exactly like bone tissue: These extraordinary objects are already made from 'metamaterials'. Researchers have now developed an AI tool that not only can discover such extraordinary materials but also makes them fabrication-ready and durable. This makes it possible to create devices with unprecedented functionalities.

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Highly reducing or oxidizing photocatalysts are a fundamental challenge in photochemistry. Only a few transition metal complexes with Earth-abundant metal ions have so far advanced to excited state oxidants, including chromium, iron, and cobalt. All these photocatalysts require high energy light for excitation and their oxidizing power has not yet been fully exploited. Furthermore, precious and hence expensive metals are the decisive ingredients in most cases. A team of researchers has now developed a new molecular system based on the element manganese. Manganese, as opposed to precious metals, is the third most abundant metal after iron and titanium and hence widely available and very cheap.

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Wherever hot water flows, limescale is never far away. In households, this is a nuisance; in thermal power stations, it's an expensive problem. Now researchers have found an answer.

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The past year has seen major advances in Large Language Models (LLMs) such as ChatGPT. The ability of these models to interpret and produce human text sources (and other sequence data) has implications for people in many areas of human activity. A new perspective paper argues that like many professionals, neuroscientists can either benefit from partnering with these powerful tools or risk being left behind.

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Researchers have identified a new way to harness the antioxidant and antibacterial properties of a botanical compound to make nanofiber-coated cotton bandages that fight infection and help wounds heal more quickly.

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Engineers have pioneered a new way to visualize the smallest protein clusters, skirting the physical limitations of light-powered microscopes and opening new avenues for detecting the proteins implicated in diseases like Alzheimer's and testing new treatments.

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A novel PET imaging technique can noninvasively detect active inflammation in the body before clinical symptoms arise, according to new research. Using a PET tracer that binds to proteins present on activated immune cells, the technique produces images of ongoing inflammation throughout the body, such as rheumatoid arthritis. This makes it easier for physicians to correctly diagnose and treat patients.

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A new fusion of materials, each with special electrical properties, has all the components required for a unique type of superconductivity that could provide the basis for more robust quantum computing.

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An advanced human heart organoid system can be used to model embryonic heart development under pregestational diabetes-like conditions, researchers report. The organoids recapitulate hallmarks of pregestational diabetes-induced congenital heart disease found in mice and humans. The findings also showed that endoplasmic reticulum (ER) stress and lipid imbalance are critical factors contributing to these disorders, which could be ameliorated with exposure to omega-3s.