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Categories: Chemistry: Organic Chemistry, Mathematics: Statistics
Published Do genes-in-pieces code for proteins that fold in pieces?
(via sciencedaily.com) Original source A new study offers new insights into the evolution of foldable proteins.
Published Chemists synthesize an improved building block for medicines
(via sciencedaily.com) Original source Research could help drug developers improve the safety profiles of medications and reduce side effects.
Published Using visible light to make pharmaceutical building blocks
(via sciencedaily.com) Original source Chemists have discovered a way to use visible light to synthesize a class of compounds particularly well suited for use in pharmaceuticals. The class of compounds, called azetidines, had been previously identified as a good candidate to build therapeutic drugs, but the compounds are difficult to produce in chemical reactions. Now, a team has developed a method to produce a specific class of azetidines called monocyclic azetidines using visible light and a photocatalyst.
Published Novel spectroscopy technique sheds light on NOx reduction
(via sciencedaily.com) Original source The process that can convert pollution into benign by-products is called selective catalytic reduction, or SCR. Until now, it has been unclear how this reaction actually occurs, and contradictions have long existed between reaction models within the literature. Catalysis researchers used a technology called modulation excitation spectroscopy, or MES, to finally identify the correct pathway.
Published No more stressing out over structural formulas
(via sciencedaily.com) Original source Structural formulas are a source of dread for many students, but they're an essential tool in biology lessons. A study has now shown that the stress levels of students working with chemical formulas are significantly reduced if they are given simple tips on how to deal with these formulas.
Published New materials: Synthetic pathway for promising nitride compounds discovered
(via sciencedaily.com) Original source Chemists have successfully synthesized Ruddlesden-Popper nitrides for the first time, opening the door to new materials with unique properties.
Published Aromatic compounds: A ring made up solely of metal atoms
(via sciencedaily.com) Original source The term aromaticity is a basic, long-standing concept in chemistry that is well established for ring-shaped carbon compounds. Aromatic rings consisting solely of metal atoms were, however, heretofore unknown. A research team recently succeeded in isolating such a metal ring and describing it in full.
Published Scientists use computational modeling to guide a difficult chemical synthesis
(via sciencedaily.com) Original source Researchers have discovered a new way to drive chemical reactions that could generate a wide variety of azetidines -- four-membered nitrogen heterocycles that have desirable pharmaceutical properties.
Published New, holistic way to teach synthetic biology
(via sciencedaily.com) Original source Synthetic biology combines principles from science, engineering and social science, creating emerging technologies such as alternative meats and mRNA vaccines; Deconstructing synthetic biology across scales gives rise to new approach to uniting traditional disciplines; Case studies offer a modular, accessible approach to teaching at different institutions.
Published Solar technology: Innovative light-harvesting system works very efficiently
(via sciencedaily.com) Original source Researchers are reporting progress on the road to more efficient utilization of solar energy: They have developed an innovative light-harvesting system.
Published New tool enables faster, more cost-effective genome editing of traits to improve agriculture sustainability
(via sciencedaily.com) Original source New research had the goal of reducing the time and cost it takes to bring an improved crop to the marketplace to improve agriculture sustainability.
Published Towards non-toxic antifouling agents: A novel method for total synthesis of scabrolide F
(via sciencedaily.com) Original source Norcembranolide diterpenes, isolated from the soft corals of the genus Sinularia, are important compounds for the development of new drugs, owing to their diverse biological activities. However, total synthesis methods for these compounds are scarce. Now, a team of researchers has achieved the total synthesis of scabrolide F, a norcembranolide diterpene. They also revealed its non-toxic antifouling properties. This novel method can lead to the development of new drugs and antifouling agents.
Published Balancing act: Novel wearable sensors and AI transform balance assessment
(via sciencedaily.com) Original source Traditional methods to assess balance often suffer from subjectivity, aren't comprehensive enough and can't be administered remotely. They also are expensive and require specialized equipment and clinical expertise. Using wearable sensors and advanced machine learning algorithms, researchers offer a practical and cost-effective solution for capturing detailed movement data, essential for balance analysis. This approach is more accessible and can be administered remotely, which could have significant implications for health care, rehabilitation, sports science or other fields where balance assessment is important.
Published Researchers develop RNA-targeting technology for precisely manipulating parts of human genes
(via sciencedaily.com) Original source Researchers have harnessed a bacterial immune defense system, known as CRISPR, to efficiently and precisely control the process of RNA splicing. The technology opens the door to new applications, including systematically interrogating the functions of parts of genes and correcting splicing deficiencies that underlie numerous diseases and disorders.
Published Membrane protein analogues could accelerate drug discovery
(via sciencedaily.com) Original source Researchers have created a deep learning pipeline for designing soluble analogues of key protein structures used in pharmaceutical development, sidestepping the prohibitive cost of extracting these proteins from cell membranes.
Published Mirror-image chemicals may revolutionize drug delivery
(via sciencedaily.com) Original source More than 130 years after cyclodextrins were first discovered and reported, a team of scientists has created chemical mirror images of these complex carbohydrates in the laboratory. This discovery may revolutionize how medications are delivered to patients.
Published New material puts eco-friendly methanol conversion within reach
(via sciencedaily.com) Original source Researchers have developed innovative, eco-friendly quantum materials that can drive the transformation of methanol into ethylene glycol. This discovery opens up new possibilities for using eco-friendly materials in photocatalysis, paving the way for sustainable chemical production.
Published Custom-made molecules designed to be invisible while absorbing near-infrared light
(via sciencedaily.com) Original source Researchers used theoretical calculations assessing electron orbital symmetry to synthesize new molecule designed to be both transparent and colorless while absorbing near-infrared light. This compound demonstrates the first systematic approach to producing such materials and have applications in advanced electronics. This compound also shows semiconducting properties.
Published Golden ball mills as green catalysts
(via sciencedaily.com) Original source A gold-coated milling vessel for ball mills proved to be a real marvel: without any solvents or environmentally harmful chemicals, the team was able to use it to convert alcohols into aldehydes. The catalytic reaction takes place at the gold surface and is mechanically driven. The vessel can be reused multiple times. 'This opens up new prospects for the use of gold in catalysis and shows how traditional materials can contribute to solving modern environmental problems in an innovative way,' says Borchardt.
Published Molecular sponge for the electronics of the future
(via sciencedaily.com) Original source An international research team has succeeded in developing a new type of material in the rather young research field of covalent organic frameworks. The new two-dimensional polymer is characterized by the fact that its properties can be controlled in a targeted and reversible manner. This has brought the researchers a step closer to the goal of realizing switchable quantum states.