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Categories: Chemistry: Biochemistry, Mathematics: Statistics
Published Harnessing incoherence to make sense of real-world networks
(via sciencedaily.com) A new way of describing the connections in real-world systems such as food webs or social networks could lead to better methods for predicting and controlling them.
Published Another crystalline layer on crystal surface as a precursor of crystal-to-crystal transition
(via sciencedaily.com) Ice surfaces have a thin layer of water below its melting temperature of 0 degrees Celsius. Such premelting phenomenon is important for skating and snowflake growth. Similarly, liquid often crystallizes into a thin layer of crystal on a flat substrate before reaching its freezing temperature, i.e. prefreezing. The thickness of the surface layer usually increases and diverges as approaching the phase transition (such as melting and freezing) temperature. Besides premelting and prefreezing, whether similar surface phenomenon exists as a precursor of a phase transition has rarely been explored. Scientists now propose that a polymorphic crystalline layer may form on a crystal surface before the crystal-crystal phase transition and names it pre-solid-solid transition.
Published Protein engineers navigate toward more targeted therapeutics
(via sciencedaily.com) Researchers uncovered the role of the third intracellular loop in the G protein-coupled receptors' signaling mechanism, which could lead to a more targeted approach to drug discovery and a paradigm shift for new therapeutics.
Published New approach to harvesting aerial humidity with organic crystals
(via sciencedaily.com) Researchers have reported a novel method of harvesting water from naturally occurring sources such as fog and dew.
Published Modelling superfast processes in organic solar cell material
(via sciencedaily.com) In organic solar cells, carbon-based polymers convert light into charges that are passed to an acceptor. Scientists have now calculated how this happens by combining molecular dynamics simulations with quantum calculations and have provided theoretical insights to interpret experimental data.
Published Major advance in super-resolution fluorescence microscopy
(via sciencedaily.com) Pushing the MINFLUX technique to higher spatial and temporal precision allows protein dynamics to be observed under physiological conditions.
Published Genetics as conservation tool for endangered chimpanzees
(via sciencedaily.com) The western chimpanzees of Guinea are threatened by mining activities. Using a novel genetic approach, researchers have collected information on population size and community structure of the endangered species. These data provide an important baseline to assess the impact of mining.
Published Filming proteins in motion
(via sciencedaily.com) Proteins are the heavy-lifters of biochemistry. These beefy molecules act as building blocks, receptors, processors, couriers and catalysts. Naturally, scientists have devoted a lot of research to understanding and manipulating proteins.
Published Researchers control the degree of twist in nanostructured particles
(via sciencedaily.com) Micron-sized 'bow ties,' self-assembled from nanoparticles, form a variety of different curling shapes that can be precisely controlled, a research team has shown.
Published Making sense of scents: Deciphering our sense of smell
(via sciencedaily.com) Breaking a longstanding impasse in our understanding of olfaction, scientists have created the first molecular-level, 3D picture of how an odor molecule activates a human odorant receptor, a crucial step in deciphering the sense of smell.
Published 'Glow-in-the-dark' proteins could help diagnose viral diseases
(via sciencedaily.com) Despite recent advancements, many highly sensitive diagnostic tests for viral diseases still require complicated techniques to prepare a sample or interpret a result, making them impractical for point-of-care settings or areas with few resources. But now, a team has developed a sensitive method that analyzes viral nucleic acids in as little as 20 minutes and can be completed in one step with 'glow-in-the-dark' proteins.
Published Robots can help improve mental wellbeing at work -- as long as they look right
(via sciencedaily.com) Robots can be useful as mental wellbeing coaches in the workplace -- but perception of their effectiveness depends in large part on what the robot looks like.
Published How neuroimaging can be better utilized to yield diagnostic information about individuals
(via sciencedaily.com) Since the development of functional magnetic resonance imaging in the 1990s, the reliance on neuroimaging has skyrocketed as researchers investigate how fMRI data from the brain at rest, and anatomical brain structure itself, can be used to predict individual traits, such as depression, cognitive decline, and brain disorders. But how reliable brain imaging is for detecting traits has been a subject of wide debate. Researchers now report that stronger links between brain measures and traits can be obtained when state-of-the-art pattern recognition (or 'machine learning') algorithms are utilized, which can garner high-powered results from moderate sample sizes.
Published Innovative approach opens the door to COVID nanobody therapies
(via sciencedaily.com) The relatively simple and low-cost procedure could empower laboratories in low-resource areas to generate nanobodies against SARS-CoV-2, as well as other viruses.
Published Fighting intolerance with physics
(via sciencedaily.com) In a world experiencing growing inequality and intolerance, tools borrowed from science and mathematics could be the key to understanding and preventing prejudice. Experts apply evolutionary game theory, which combines techniques from economics and biology, and complex system analysis to investigate the relationship between inequality and intolerance. They found that inequality boosts intolerance and that redistribution of wealth can prevent its infectious spread.
Published Simulating cuts and burns reveals wound healing and clearing power of fibroblasts
(via sciencedaily.com) Researchers create a biomimetic model to study wound healing in burn and laceration wounds. The team designed an in vitro model system made of fibroblasts embedded in a collagen hydrogel. Wounds were created in this microtissue using a microdissection knife to mimic laceration or a high-energy laser to simulate a burn. They discovered that fibroblasts clear away damaged tissue before depositing new material. This part of the healing process is slower in burn wounds.
Published Microneedle-based drug delivery technique for plants
(via sciencedaily.com) The agriculture industry is under pressure to adopt sustainable and precise agricultural practices that enable more efficient use of resources due to worsening environmental conditions resulting from climate change, an ever-expanding human population, limited resources, and a shortage of arable land. As a result, developing delivery systems that efficiently distribute micronutrients, pesticides, and antibiotics in crops is crucial to ensuring high productivity and high-quality produce while minimising resource waste. However, current and standard practices for agrochemical application in plants are inefficient. These practices cause significant detrimental environmental side effects, such as water and soil contamination, biodiversity loss and degraded ecosystems; and public health concerns, such as respiratory problems, chemical exposure and food contamination.
Published Fats help tag medical implants as friend or foe
(via sciencedaily.com) Bioengineers found that lipid deposition on the surfaces of medical implants can play a mediating role between the body and implants, knowledge that could help scientists develop biomaterials or coatings for implants that could reduce malfunction rates.
Published Attracting stem cells and facilitating bone regeneration by adhesive protein
(via sciencedaily.com) Scientists have developed an osteogenic barrier coating material that maximizes the effect of guided bone regeneration (GBR) for implant placements.
Published Scientists transform algae into unique functional perovskites with tunable properties
(via sciencedaily.com) Scientists have transformed single-cell algae into functional perovskite materials. The team has converted mineral shells of algae into lead halide perovskites with tunable physical properties. The new perovskites have unique nano-architectures unachievable by conventional synthetic production. The method can be applied to the mass production of perovskites with tunable structural and electro-optical properties from single-celled organisms.