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Categories: Chemistry: Biochemistry, Mathematics: Statistics
Published Research on RNA editing illuminates possible lifesaving treatments for genetic diseases
(via sciencedaily.com) Original source The research explores how CRISPR can be used to edit RNA.
Published When does a conductor not conduct?
(via sciencedaily.com) Original source A new study uncovers a switchable, atomically-thin metal-organic material that could be used in future low-energy electronic technologies. The study shows that electron interactions in this material create an unusual electrically-insulating phase in which electrons are 'frozen'. By reducing the population of electrons, the authors are able to unfreeze the remaining electrons, allowing for controlled transitions between insulating and electrically-conductive phases: the key to the on-off binary operations of classical computing.
Published From disorder to order: Flocking birds and 'spinning' particles
(via sciencedaily.com) Original source Researchers have demonstrated that ferromagnetism, an ordered state of atoms, can be induced by increasing particle motility and that repulsive forces between atoms are sufficient to maintain it. The discovery not only extends the concept of active matter to quantum systems but also contributes to the development of novel technologies that rely on the magnetic properties of particles, such as magnetic memory and quantum computing.
Published Imaging technique shows new details of peptide structures
(via sciencedaily.com) Original source Researchers outline how they used a chemical probe to light up interlocking peptides. Their technique will help scientists differentiate synthetic peptides from toxic types found in Alzheimer's disease.
Published Getting dynamic information from static snapshots
(via sciencedaily.com) Original source Researchers have created TopicVelo, a powerful new method of using the static snapshots from scRNA-seq to study how cells and genes change over time. This will help researchers better study how embryos develop, cells differentiate, cancers form, and the immune system reacts.
Published Professor resolves two decades of oxide semiconductor challenges
(via sciencedaily.com) Original source Successful development of high-performance amorphous P-type oxide semiconductor using tellurium-selenium composite oxide.
Published AI deciphers new gene regulatory code in plants and makes accurate predictions for newly sequenced genomes
(via sciencedaily.com) Original source Elucidating the relationship between the sequences of non-coding regulatory elements and their target genes is key to understanding gene regulation and its variation between plant species and ecotypes. Now, an international research team developed deep learning models that link gene sequence data with mRNA copy number for several plant species and predicted the regulatory effect of gene sequence variation.
Published More efficient molecular motor widens potential applications
(via sciencedaily.com) Original source Light-driven molecular motors were first developed nearly 25 years ago. However, making these motors do actual work proved to be a challenge. In a new paper, scientists describe improvements that bring real-life applications closer.
Published Robotic nerve 'cuffs' could help treat a range of neurological conditions
(via sciencedaily.com) Original source Researchers have developed tiny, flexible devices that can wrap around individual nerve fibers without damaging them. The researchers combined flexible electronics and soft robotics techniques to develop the devices, which could be used for the diagnosis and treatment of a range of disorders, including epilepsy and chronic pain, or the control of prosthetic limbs.
Published A shortcut for drug discovery
(via sciencedaily.com) Original source For most human proteins, there are no small molecules known to bind them chemically (so called 'ligands'). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel medicines. Researchers at CeMM, in a collaboration with Pfizer, have now leveraged and scaled a method to measure the binding activity of hundreds of small molecules against thousands of human proteins. This large-scale study revealed tens of thousands of ligand-protein interactions that can now be explored for the development of chemical tools and therapeutics. Moreover, powered by machine learning and artificial intelligence, it allows unbiased predictions of how small molecules interact with all proteins present in living human cells. These groundbreaking results have been published in the journal Science (DOI: 10.1126/science.adk5864), and all generated data and models are freely available for the scientific community.
Published Estimating emissions potential of decommissioned gas wells from shale samples
(via sciencedaily.com) Original source Extracting natural gas from shale formations can provide an abundant, lower-carbon footprint fossil fuel, but also creates concerns over increased methane emissions. Researchers have now developed a new tool that can estimate the emission potential of shale wells after they are no longer active.
Published Nanomaterial that mimics proteins could be basis for new neurodegenerative disease treatments
(via sciencedaily.com) Original source A newly developed nanomaterial that mimics the behavior of proteins could be an effective tool for treating Alzheimer's and other neurodegenerative diseases. The nanomaterial alters the interaction between two key proteins in brain cells -- with a potentially powerful therapeutic effect.
Published 'Like a nanoscopic Moon lander': Scientists unlock secret of how pyramidal molecules move across surfaces
(via sciencedaily.com) Original source Scientists have watched a molecule move across a graphite surface in unprecedented detail. It turns out this particular molecule moves like a Moon lander -- and the insights hold potential for future nanotechnologies.
Published Towards novel promising perovskite-type ferroelectric materials: High-pressure synthesis of rubidium niobate
(via sciencedaily.com) Original source Researchers have pioneered a breakthrough in ferroelectric material development. They've engineered a novel displacement-type ferroelectric material boasting remarkable dielectric properties. Their achievement includes the successful synthesis of rubidium niobate (RbNbO3), a compound previously deemed challenging to produce under pressures exceeding 40,000 atmospheres. Additionally, they characterized how polarization changes across a wide temperature range during phase transitions. This breakthrough can lead to new design guidelines for ferroelectric materials.
Published The secret to saving old books could be gluten-free glues
(via sciencedaily.com) Original source 'Bookworm' is a cute thing to call a voracious reader, but actual bookworms -- as well as microorganisms and time -- break down the flour pastes commonly used to keep old publications in one piece. Now, researchers have analyzed the proteins in wheat-based glues applied in historic bookbinding to provide insights on their adhesiveness and how they degrade. This information could help conservators restore and preserve treasured tomes for future generations.
Published Why can't robots outrun animals?
(via sciencedaily.com) Original source Robotics engineers have worked for decades and invested many millions of research dollars in attempts to create a robot that can walk or run as well as an animal. And yet, it remains the case that many animals are capable of feats that would be impossible for robots that exist today.
Published Pattern formation in the nano-cosmos
(via sciencedaily.com) Original source A new model extends the theory of elastic phase separation towards nanoscopic structures. Such patterns are frequent in biological systems and also used in nano-engineering to create structural color. With their new insights, the scientists can predict the length scale of nanoscopic patterns and thus control them during production.
Published Biophysics: Testing how well biomarkers work
(via sciencedaily.com) Original source Researchers have developed a method to determine how reliably target proteins can be labeled using super-resolution fluorescence microscopy.
Published A chemical mystery solved -- the reaction explaining large carbon sinks
(via sciencedaily.com) Original source A mystery that has puzzled the scientific community for over 50 years has finally been solved. A team has discovered that a certain type of chemical reaction can explain why organic matter found in rivers and lakes is so resistant to degradation.
Published Condensed matter physics: Novel one-dimensional superconductor
(via sciencedaily.com) Original source In a significant development in the field of superconductivity, researchers have successfully achieved robust superconductivity in high magnetic fields using a newly created one-dimensional (1D) system. This breakthrough offers a promising pathway to achieving superconductivity in the quantum Hall regime, a longstanding challenge in condensed matter physics.