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Categories: Chemistry: Biochemistry, Mathematics: Statistics

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Researchers have developed a new nanoparticle that can 'hitch a ride' on immune cells, or monocytes. Because of its tiny size, the particle can tag along directly into lymph nodes and help metastasis show up on MRIs where it would otherwise be too hard to detect. The process offers game-changing benefits for the early detection of cancer metastasis in the lymph nodes. While previously, metastasis could only be assessed by an increase in lymph node size; the new particles could lead to MRI contrast agents that can highlight metastatic cells in lymph nodes that may otherwise appear normal.

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Researchers are further improving CRISPR's versatility to engineer new grasses and yeasts for biochemical production.

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Researchers have used equipment originally intended for astronomy observation to capture transformations in the nuclear structure of atomic nuclei, reports a new study.

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The properties of supramolecular polymers are dictated by the self-assembled state of the molecules. However, not much is known about the impact of morphologies on the properties of nano- and mesoscopic-scale polymeric assemblies. Recently, a research team demonstrated how terminus-free toroids and random coils derived from the same luminescent molecule show different photophysical properties. The team also presented a novel method for purifying the toroidal structure.

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Chiral skyrmions are a special type of spin textures in magnetic materials with asymmetric exchange interactions. They can be treated as quasi-particles and carry integer topological charges. Scientists have recently studied the random walk-behaviors of chiral skyrmions by simulating their dynamics within a ferromagnetic layer surrounded by chiral flower-like obstacles. The simulations reveal that the system behaves like a topological sorting device, indicating its use in information processing and computing devices.

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A team of scientists have demonstrated the first successful use of a neural prosthetic device to recall specific memories.

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You can mend a broken heart this valentine s day now that researchers invented a new hydrogel that can be used to heal damaged heart tissue and improve cancer treatments.

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Fossils of a marine animal that lived 500 million years ago, combined with computer simulations, informed the design of a new soft robot.

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Scientists have discovered that a known practice in information technology can also be applied to chemistry. Researchers found that to enhance the sampling in chemical simulations, all you need to do is stop and restart.

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A coating that can hide objects in plain sight, or an implant that behaves exactly like bone tissue: These extraordinary objects are already made from 'metamaterials'. Researchers have now developed an AI tool that not only can discover such extraordinary materials but also makes them fabrication-ready and durable. This makes it possible to create devices with unprecedented functionalities.

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Highly reducing or oxidizing photocatalysts are a fundamental challenge in photochemistry. Only a few transition metal complexes with Earth-abundant metal ions have so far advanced to excited state oxidants, including chromium, iron, and cobalt. All these photocatalysts require high energy light for excitation and their oxidizing power has not yet been fully exploited. Furthermore, precious and hence expensive metals are the decisive ingredients in most cases. A team of researchers has now developed a new molecular system based on the element manganese. Manganese, as opposed to precious metals, is the third most abundant metal after iron and titanium and hence widely available and very cheap.

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A team of scientists has devised means for classical computing to mimic a quantum computing with far fewer resources than previously thought. The scientists' results show that classical computing can be reconfigured to perform faster and more accurate calculations than state-of-the-art quantum computers.

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Wherever hot water flows, limescale is never far away. In households, this is a nuisance; in thermal power stations, it's an expensive problem. Now researchers have found an answer.

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Researchers have identified a new way to harness the antioxidant and antibacterial properties of a botanical compound to make nanofiber-coated cotton bandages that fight infection and help wounds heal more quickly.

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Engineers have pioneered a new way to visualize the smallest protein clusters, skirting the physical limitations of light-powered microscopes and opening new avenues for detecting the proteins implicated in diseases like Alzheimer's and testing new treatments.

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A novel PET imaging technique can noninvasively detect active inflammation in the body before clinical symptoms arise, according to new research. Using a PET tracer that binds to proteins present on activated immune cells, the technique produces images of ongoing inflammation throughout the body, such as rheumatoid arthritis. This makes it easier for physicians to correctly diagnose and treat patients.

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A new fusion of materials, each with special electrical properties, has all the components required for a unique type of superconductivity that could provide the basis for more robust quantum computing.

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An advanced human heart organoid system can be used to model embryonic heart development under pregestational diabetes-like conditions, researchers report. The organoids recapitulate hallmarks of pregestational diabetes-induced congenital heart disease found in mice and humans. The findings also showed that endoplasmic reticulum (ER) stress and lipid imbalance are critical factors contributing to these disorders, which could be ameliorated with exposure to omega-3s.

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The ability to detect diseases at an early stage or even predict their onset would be of tremendous benefit to doctors and patients alike. A research team now develops intelligent, miniaturized biosensor devices and systems using nanomaterials to determine biomolecules and cells as well as biochemical reactions or processes as disease markers. The team's current publication describes the development of a portable, palm-sized test system that can simultaneously carry out up to thirty-two analyses of one sample.

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Carboxylic acid dianions (fumarate, maleate and succinate) play a role in coordination chemistry and to some extent also in the biochemistry of body cells. A team has now analyzed their electronic structures using RIXS in combination with DFT simulations. The results provide information not only on electronic structures but also on the relative stability of these molecules which can influence an industry's choice of carboxylate dianions, optimizing both the stability and geometry of coordination polymers.