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Categories: Chemistry: Organic Chemistry, Ecology: Extinction
Published New model offers a way to speed up drug discovery
(via sciencedaily.com) Original source A model known as ConPLex can predict whether potential drug molecules will interact with specific protein targets, without having to perform the computationally intensive calculation of the molecules' structures. By applying a language model to protein-drug interactions, researchers can quickly screen large libraries of potential drug compounds.
Published Ancient herbivore's diet weakened teeth leading to eventual starvation, study suggests
(via sciencedaily.com) Original source Researchers have shed light on the life of the ancient reptile Rhynchosaur, which walked the earth between 250-225 million years ago, before being replaced by the dinosaurs.
Published Sustainable technique to manufacture chemicals
(via sciencedaily.com) Original source A newly published study details a novel mechanochemistry method that can produce chemicals using less energy and without the use of solvents that produce toxic waste.
Published Lost giants: New study reveals the abundance decline of African megafauna
(via sciencedaily.com) Original source A groundbreaking new paper focuses on the size and abundance of living and fossil African large mammals, shedding light on the ecological dynamics behind the decline of these iconic creatures. The findings challenge previous assumptions about the causes of megafaunal extinctions in Africa and provide new insights into the restructuring of ecosystems over millions of years.
Published Breakthrough: Scientists develop artificial molecules that behave like real ones
(via sciencedaily.com) Original source Scientists have developed synthetic molecules that resemble real organic molecules. A collaboration of researcher can now simulate the behavior of real molecules by using artificial molecules.
Published A new way to develop drugs without side effects
(via sciencedaily.com) Original source Have you ever wondered how drugs reach their targets and achieve their function within our bodies? If a drug molecule or a ligand is a message, an inbox is typically a receptor in the cell membrane. One such receptor involved in relaying molecular signals is a G protein-coupled receptor (GPCR). About one-third of existing drugs work by controlling the activation of this protein. Researchers now reveal a new way of activating GPCR by triggering shape changes in the intracellular region of the receptor. This new process can help researchers design drugs with fewer or no side effects.
Published Water molecules define the materials around us
(via sciencedaily.com) Original source A new paper argues that materials like wood, bacteria, and fungi belong to a newly identified class of matter, 'hydration solids.' The new findings emerged from ongoing research into the strange behavior of spores, dormant bacterial cells.
Published Coral disease tripled in the last 25 years. Three-quarters will likely be diseased by next century
(via sciencedaily.com) Original source Research suggests warming temperatures will see nearly 80 per cent of coral in reefs diseased in the next 80 years.
Published More complex than expected: Catalysis under the microscope
(via sciencedaily.com) Original source Usually, catalytic reactions are analyzed by checking which chemicals go into a chemical reactor and which come out. But as it turns out, in order to properly understand and optimize catalysts, much more information is necessary. Scientists developed methods to watch catalytic reactions with micrometer resolution under the microscope -- and the process is much more complex than previously thought.
Published Illuminating the molecular ballet in living cells
(via sciencedaily.com) Original source Researchers have developed one of the world's fastest cameras capable of detecting fluorescence from single molecules.
Published Viruses hidden in coral symbiont's genetic material are a potential threat to reefs
(via sciencedaily.com) Original source Microscopic algae that corals need for survival harbor a common and possibly disease-causing virus in their genetic material.
Published Air quality stations have collected vast stores of DNA by accident, a potentially 'game-changing' discovery for tracking global biodiversity
(via sciencedaily.com) Original source The accelerating loss of biodiversity and increasing rate of species extinction is a major threat to ecosystems around the globe. And yet, quantifying those losses at a large scale hasn't been possible, in large part due to a lack of the required infrastructure. But a new study shows that a major source for such information already exists in the form of environmental DNA (eDNA), which has been inadvertently collected in filters by thousands of ambient air quality monitoring stations in countries around the world for decades.
Published CRISPR/Cas9 reveals a key gene involved in the evolution of coral skeleton formation
(via sciencedaily.com) Original source New work uses cutting-edge CRISPR/Cas9 genome editing tools to reveal a gene that's critical to stony corals' ability to build their reef architectures. This research could inform coral conservation and restoration efforts.
Published Genomes of 233 primate species sequenced
(via sciencedaily.com) Original source Researchers from 24 countries have analyzed the genomes of 809 individuals from 233 primate species, generating the most complete catalog of genomic information about our closest relatives to date. The project provides new insights into the evolution of primates, including humans, and their diversity. In baboons, for example, hybridization and gene flow between different species occurred in the past and is still ongoing in several regions of their range. This makes baboons a good model for the evolution of early human lineages within and outside Africa. In addition, using a specially designed AI algorithm, the genomic data enable new insights into the genetic causes of human diseases.
Published Flat fullerene fragments attractive to electrons
(via sciencedaily.com) Original source Researchers have gained new insights into the unique chemical properties of spherical molecules composed entirely of carbon atoms, called fullerenes. They did it by making flat fragments of the molecules, which surprisingly retained and even enhanced some key chemical properties.
Published Lab-grown mini lungs could accelerate the study of respiratory diseases
(via sciencedaily.com) Original source Researchers have collaborated to refine a cell culture technology platform that grows genetically identical lung buds from human embryonic stem cells.
Published Forest birds with short, round wings more sensitive to habitat fragmentation
(via sciencedaily.com) Original source Tropical forest birds, which tend to have wings that are short and round relative to their body length and shape, are more sensitive to habitat fragmentation than the long-, slender-winged species common in temperate forests.
Published Study identifies boat strikes as a growing cause of manatee deaths in Belize
(via sciencedaily.com) Original source The endangered Antillean manatee faces a growing threat from boat strikes in Belize, according to a new study that raises concerns about the survival of what had been considered a relatively healthy population. Belize hosts a population of around 1,000 manatees. With the growth of tourism in recent decades, however, Belize has seen a substantial increase in boat traffic, making boat strikes an increasingly important cause of manatee deaths and injuries.
Published You can make carbon dioxide filters with a 3D printer
(via sciencedaily.com) Original source Researchers demonstrated that it's possible to make carbon dioxide capture filters using 3D printing.
Published A protein mines, sorts rare earths better than humans, paving way for green tech
(via sciencedaily.com) Original source Rare earth elements, like neodymium and dysprosium, are a critical component to almost all modern technologies, from smartphones to hard drives, but they are notoriously hard to separate from the Earth's crust and from one another. Scientists have discovered a new mechanism by which bacteria can select between different rare earth elements, using the ability of a bacterial protein to bind to another unit of itself, or 'dimerize,' when it is bound to certain rare earths, but prefer to remain a single unit, or 'monomer,' when bound to others.