Showing 20 articles starting at article 161
< Previous 20 articles Next 20 articles >
Categories: Chemistry: Organic Chemistry, Ecology: Trees
Published Research on RNA editing illuminates possible lifesaving treatments for genetic diseases
(via sciencedaily.com) Original source The research explores how CRISPR can be used to edit RNA.
Published When does a conductor not conduct?
(via sciencedaily.com) Original source A new study uncovers a switchable, atomically-thin metal-organic material that could be used in future low-energy electronic technologies. The study shows that electron interactions in this material create an unusual electrically-insulating phase in which electrons are 'frozen'. By reducing the population of electrons, the authors are able to unfreeze the remaining electrons, allowing for controlled transitions between insulating and electrically-conductive phases: the key to the on-off binary operations of classical computing.
Published Getting dynamic information from static snapshots
(via sciencedaily.com) Original source Researchers have created TopicVelo, a powerful new method of using the static snapshots from scRNA-seq to study how cells and genes change over time. This will help researchers better study how embryos develop, cells differentiate, cancers form, and the immune system reacts.
Published A shortcut for drug discovery
(via sciencedaily.com) Original source For most human proteins, there are no small molecules known to bind them chemically (so called 'ligands'). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel medicines. Researchers at CeMM, in a collaboration with Pfizer, have now leveraged and scaled a method to measure the binding activity of hundreds of small molecules against thousands of human proteins. This large-scale study revealed tens of thousands of ligand-protein interactions that can now be explored for the development of chemical tools and therapeutics. Moreover, powered by machine learning and artificial intelligence, it allows unbiased predictions of how small molecules interact with all proteins present in living human cells. These groundbreaking results have been published in the journal Science (DOI: 10.1126/science.adk5864), and all generated data and models are freely available for the scientific community.
Published Nanomaterial that mimics proteins could be basis for new neurodegenerative disease treatments
(via sciencedaily.com) Original source A newly developed nanomaterial that mimics the behavior of proteins could be an effective tool for treating Alzheimer's and other neurodegenerative diseases. The nanomaterial alters the interaction between two key proteins in brain cells -- with a potentially powerful therapeutic effect.
Published The longer spilled oil lingers in freshwater, the more persistent compounds it produces
(via sciencedaily.com) Original source Oil is an important natural resource for many industries, but it can lead to serious environmental damage when accidentally spilled. While large oil spills are highly publicized, every year there are many smaller-scale spills into lakes, rivers and oceans. The longer that oil remains in freshwater, the more chemical changes it undergoes, creating products that can persist in the environment.
Published The secret to saving old books could be gluten-free glues
(via sciencedaily.com) Original source 'Bookworm' is a cute thing to call a voracious reader, but actual bookworms -- as well as microorganisms and time -- break down the flour pastes commonly used to keep old publications in one piece. Now, researchers have analyzed the proteins in wheat-based glues applied in historic bookbinding to provide insights on their adhesiveness and how they degrade. This information could help conservators restore and preserve treasured tomes for future generations.
Published Hurricanes jeopardize carbon-storing New England forests
(via sciencedaily.com) Original source Many American companies are relying on carbon offsets to reduce their carbon footprint, especially those who have pledged to achieve 'net-zero emissions.' Sequestering carbon in forests is an example of a nature-based solution that is being used to address climate change, but a new study suggests that hurricanes could pose a risk. The results show that a single hurricane may wipe out 5% to 10% of total above-ground forest carbon, through tree damage, in New England.
Published Diversity and productivity go branch-in-branch
(via sciencedaily.com) Original source Researchers found that forests with higher trait diversity not only adapt better to climate change but may also thrive. The study unveiled how tree functional trait diversity plays a pivotal role in mitigating climate warming. In the face of environmental stress, these diverse trees have been shown to maintain higher productivity levels, in contrast to monoculture forests.
Published Biophysics: Testing how well biomarkers work
(via sciencedaily.com) Original source Researchers have developed a method to determine how reliably target proteins can be labeled using super-resolution fluorescence microscopy.
Published A chemical mystery solved -- the reaction explaining large carbon sinks
(via sciencedaily.com) Original source A mystery that has puzzled the scientific community for over 50 years has finally been solved. A team has discovered that a certain type of chemical reaction can explain why organic matter found in rivers and lakes is so resistant to degradation.
Published World's chocolate supply threatened by devastating virus
(via sciencedaily.com) Original source A rapidly spreading virus threatens the health of the cacao tree and the dried seeds from which chocolate is made, jeopardizing the global supply of the world's most popular treat. Researchers have developed a new strategy: using mathematical data to determine how far apart farmers can plant vaccinated trees to prevent mealybugs from jumping from one tree to another and spreading the virus.
Published Researchers create artificial cells that act like living cells
(via sciencedaily.com) Original source Researchers describe the steps they took to manipulate DNA and proteins -- essential building blocks of life -- to create cells that look and act like cells from the body. This accomplishment, a first in the field, has implications for efforts in regenerative medicine, drug delivery systems and diagnostic tools.
Published New copper-catalyzed C-H activation strategy
(via sciencedaily.com) Original source Inspired by what human liver enzymes can do, chemists have developed a new set of copper-catalyzed organic synthesis reactions for building and modifying pharmaceuticals and other molecules. The new reactions are expected to be widely used in drug discovery and optimization, as well as in other chemistry-based industries.
Published Light show in living cells
(via sciencedaily.com) Original source Observing proteins precisely within cells is extremely important for many branches of research but has been a significant technical challenge -- especially in living cells, as the required fluorescent labeling had to be individually attached to each protein. The research group has now overcome this hurdle: With a method called 'vpCells,' it is possible to label many proteins simultaneously, using five different fluorescent colors.
Published From defects to order: Spontaneously emerging crystal arrangements in perovskite halides
(via sciencedaily.com) Original source A new hybrid layered perovskite featuring elusive spontaneous defect ordering has been found, report scientists. By introducing specific concentrations of thiocyanate ions into FAPbI3 (FA = formamidinium), they observed that ordered columnar defects appeared in the stacked crystalline layers, taking up one-third of the lattice space. These findings could pave the way to an innovative strategy for adjusting the properties of hybrid perovskites, leading to practical advances in optoelectronics and energy generation.
Published Researchers advance pigment chemistry with moon-inspired reddish magentas
(via sciencedaily.com) Original source A researcher who made color history in 2009 with a vivid blue pigment has developed durable, reddish magentas inspired by lunar mineralogy and ancient Egyptian chemistry.
Published Tropical forests can't recover naturally without fruit-eating birds
(via sciencedaily.com) Original source Natural forest regeneration is hailed as a cost-effective way to restore biodiversity and sequester carbon. However, the fragmentation of tropical forests has restricted the movement of large birds limiting their capacity to disperse seeds and restore healthy forests.
Published Innovative antiviral defense with new CRISPR tool
(via sciencedaily.com) Original source The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate. Scientists have devised a solution: Cas13d-NCS. This new molecular tool allows CRISPR RNA molecules that are located within the nucleus of a cell to move to the cytoplasm, making it highly effective at neutralizing RNA viruses. This advancement opens doors for precision medicine and proactive viral defense strategies.
Published A new spin on organic shampoo makes it sudsier, longer lasting
(via sciencedaily.com) Original source While there's no regulation in the U.S. for what's in organic shampoos, they tend to contain ingredients perceived as safe or environmentally friendly. However, these 'clean' shampoos separate and spoil faster than those made with synthetic stabilizers and preservatives. Now, researchers demonstrate that a simple process -- spinning organic shampoo at high speeds -- improved the final products' shelf lives and ability to clean hair.