Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

Newfound mechanism suggests drug combination could starve pancreatic cancer      (via sciencedaily.com)     Original source 

A study found that a new combination of treatments safely decreased growth of pancreatic cancer in mice by preventing cancer cells from scavenging for fuel.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

Epigenetic regulator MOF drives mitochondrial metabolism      (via sciencedaily.com)     Original source 

Researchers have unveiled a new mechanism for regulating mitochondrial function. The findings reveal the critical role played by the enzymatic activity of the lysine acetyltransferase MOF in maintaining mitochondrial integrity and function through acetylation of mitochondrial electron transport chain component COX17. Cells lacking MOF-mediated COX17 acetylation exhibit dramatic mitochondrial defects and impaired ability to produce energy. Underscoring the clinical relevance of these findings, the team also showed that cells from human patients with a developmental disorder caused by mutations in MOF also exhibited respiratory defects that could be ameliorated by interventions such as acetylation-mimetic COX17 or mitochondrially targeted MOF.

Biology: Biochemistry Biology: General Biology: Zoology
Published

Space weather disrupts nocturnal bird migration, study finds      (via sciencedaily.com)     Original source 

It's well-known that birds and other animals rely on Earth's magnetic field for long-distance navigation during seasonal migrations. But how do periodic disruptions of the planet's magnetic field, caused by solar flares and other energetic outbursts, affect the reliability of those biological navigation systems?  

Biology: Biochemistry Biology: Evolutionary Biology: General Ecology: Animals Ecology: Nature
Published

Long-term lizard study challenges the rules of evolutionary biology      (via sciencedaily.com)     Original source 

Researchers measured natural selection in four Anolis lizard species in the wild for five consecutive time periods over three years. This long-term study in a community of lizards reveals how evolution unfolds in the wild across multiple species. 

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Marine Biology: Zoology Ecology: Research Ecology: Sea Life
Published

Consistent metabolism may prove costly for insects in saltier water      (via sciencedaily.com)     Original source 

Increased salinity usually spells trouble for freshwater insects like mayflies. A new study finds that the lack of metabolic responses to salinity may explain why some freshwater insects often struggle in higher salinity, while other freshwater invertebrates (like mollusks and crustaceans) thrive. 

Biology: Biochemistry Biology: Evolutionary Biology: General Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals Paleontology: Fossils Paleontology: General
Published

Ginger pigment molecules found in fossil frogs      (via sciencedaily.com) 

Palaeontologists discover molecular evidence of phaeomelanin, the pigment that produces ginger coloration. Phaeomelanin is now toxic to animals – this discovery may be first step in understand its evolution. 

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

How male mosquitoes compensate for having only one X chromosome      (via sciencedaily.com) 

Researchers have discovered the master regulator responsible for balancing the expression of X chromosome genes between males and females in the malaria mosquito. This discovery helps scientists better understand the evolution of the epigenetic mechanisms responsible for equalizing gene expression between the sexes. The findings may contribute to the development of new ways to prevent the spread of malaria.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

New discovery may 'unlock' the future of infectious disease and cancer treatment      (via sciencedaily.com)     Original source 

Researchers have identified a 'guard mechanism' for a protein which attacks microbes in infected cells, opening the possibility of new treatments for Toxoplasma, Chlamydia, Tuberculosis and even cancer.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

The end of genes: Routine test reveals unique divergence in genetic code      (via sciencedaily.com)     Original source 

Scientists testing a new method of sequencing single cells have unexpectedly changed our understanding of the rules of genetics. The genome of a protist has revealed a seemingly unique divergence in the DNA code signalling the end of a gene, suggesting the need for further research to better understand this group of diverse organisms.  

Biology: Biochemistry Biology: Botany Biology: Cell Biology Biology: General Environmental: General Geoscience: Earth Science Geoscience: Environmental Issues Geoscience: Geochemistry
Published

Plants could worsen air pollution on a warming planet      (via sciencedaily.com)     Original source 

New research shows that plants such as oak and poplar trees will emit more of a compound called isoprene as global temperatures climb. Isoprene from plants represents the highest flux of hydrocarbons to the atmosphere after methane. Although isoprene isn’t inherently bad — it actually helps plants better tolerate insect pests and high temperatures — it can worsen air pollution by reacting with nitrogen oxides from automobiles and coal-fired power plants. The new publication can help us better understand, predict and potentially mitigate the effects of increased isoprene emission as the planet warms.

Biology: Biochemistry Biology: Evolutionary Biology: General Biology: Zoology
Published

Researchers propose radical change in how animal facial expressions are defined and studied      (via sciencedaily.com)     Original source 

Researchers have developed a new method to analyze facial expressions, as part of efforts to better understand animal communication.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular Chemistry: Biochemistry
Published

New open-source method to improve decoding of single-cell data      (via sciencedaily.com)     Original source 

Researchers have developed a new open-source computational method, dubbed Spectra, which improves the analysis of single-cell transcriptomic data. By guiding data analysis in a unique way, Spectra can offer new insights into the complex interplay between cells — like the interactions between cancer cells and immune cells, which are critical to improving immunotherapy treatments.

Biology: Biochemistry Biology: General Biology: Zoology Ecology: Animals Ecology: Endangered Species Ecology: Extinction Ecology: Nature
Published

Fear of humans pervades the South African savanna      (via sciencedaily.com)     Original source 

Mammals living in South Africa's Greater Kruger National Park, home to one of the world's largest remaining lion populations, are far more afraid of hearing human voices than lion vocalizations or hunting sounds such as dogs barking or gunshots.

Biology: Botany Biology: Evolutionary Biology: General Biology: Zoology Ecology: Animals Ecology: Endangered Species Ecology: Extinction Ecology: Nature Ecology: Trees Paleontology: Dinosaurs Paleontology: Early Mammals and Birds Paleontology: General
Published

Survival of the newest: the mammals that survive mass extinctions aren't as 'boring' as scientists thought      (via sciencedaily.com)     Original source 

For decades, scientists have assumed that mammals and their relatives that survived challenging times (like those during mass extinctions) made it because they were generalists that were able to eat just about anything and adapt to whatever life threw at them. A new study into the mammal family tree through multiple mass extinctions revealed that the species that survived aren't as generic as scientists had thought: instead, having new and different traits can be the key to succeeding in the aftermath of a catastrophe.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Zoology Ecology: Animals Ecology: Extinction Ecology: Nature
Published

Ruffed grouse population more resilient than expected, genetic study finds      (via sciencedaily.com)     Original source 

Despite decades of decline, a genetic analysis of ruffed grouse reveals that Pennsylvania's state bird harbors more genetic diversity and connectivity than expected. The findings suggest that the iconic game bird could be maintained in persistent numbers if appropriate protections are implemented.

Biology: Biochemistry Biology: General Biology: Genetics
Published

Being a vegetarian may be partly in your genes      (via sciencedaily.com)     Original source 

A person's genetic makeup plays a role in determining whether they can stick to a strict vegetarian diet, a new study has found. The findings open the door to further studies that could have important implications regarding dietary recommendations and the production of meat substitutes.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Proteins roll the dice to determine bee sex      (via sciencedaily.com)     Original source 

To date it has been unclear exactly how the sex of a bee is determined. A research team comprising biologists and chemists has now identified a key gene and the molecular mechanism linked with it. They describe how this process is similar to a game involving two dice.