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Categories: Biology: General, Mathematics: Puzzles
Published The arrangement of bacteria in biofilms affects their sensitivity to antibiotics
(via sciencedaily.com) Original source Many bacteria form an antibiotic-resistant slime. Research detailing that slime's structure could help lead to new treatments.
Published Active components of ginkgo biloba may improve early cognitive recovery after stroke
(via sciencedaily.com) Original source Adults treated with 14 days of intravenous injections of ginkgo diterpene lactone meglumine (GDLM) -- a combination of biologically active components of ginkgo biloba -- after an ischemic (clot-caused) stroke had better cognitive recovery at 14 days and 90 days.
Published Resistant bacteria can remain in the body for years
(via sciencedaily.com) Original source Fighting disease-causing bacteria becomes more difficult when antibiotics stop working. People with pre-existing conditions in particular can carry resistant germs and suffer from repeated infections for years, according to a new study.
Published Plant receptors that control immunity and development share a common origin
(via sciencedaily.com) Original source Researchers have traced the origin and evolutionary trajectory of plant immune receptors. Their discovery will make it easier to identify immune receptor genes from genomic information and could help in the development of pathogen-resistant crops.
Published Gut bacteria can process dietary fiber into an anti-allergy weapon
(via sciencedaily.com) Original source Short-chain fatty acids (SCFAs), which are produced by gut bacteria from dietary fiber, regulate our immune system, but the mechanism of their action remains unknown. In a recent study, researchers investigated how SCFAs interact with mast cells, a type of white blood cell that plays a central role in allergic reactions. Their findings and insights could lead to innovative and effective anti-allergy medications, supplements, and diets, paving the way for healthier lives.
Published LSH genes associated with defining the shapes of stems, flowers and leaves required for N-fixing root nodules
(via sciencedaily.com) Original source The developmental regulators that confer the identity of N-fixing root nodules belong to a transcription factor family (LSH) more commonly associated with defining the shapes of stems, flowers and leaves.
Published Microbial research unravels a global nitrogen mystery
(via sciencedaily.com) Original source A research findings show that different AOM lineages employ different regulatory strategies for ammonia or urea utilization, thereby minimizing direct competition with one another and allowing for coexistence.
Published Shining a new light on the tug-of-war between virus and host
(via sciencedaily.com) Original source The interplay between ribonucleic acid (RNA) and proteins is not only important for maintaining cellular homeostasis but is also at the center of the tug-of-war between virus and host. Until now, there has been no method to globally map direct interactions of individual RNA regions in an unbiased fashion without the need for genetic modification of the target RNA or cell. Researchers have now developed a breakthrough tool that overcomes this limitation.
Published Swarming cicadas, stock traders, and the wisdom of the crowd
(via sciencedaily.com) Original source The springtime emergence of vast swarms of cicadas can be explained by a mathematical model of collective decision-making with similarities to models describing stock market crashes.
Published Climate change threatens older elephants most, jeopardizing African elephants' future
(via sciencedaily.com) Original source A collaborative team of researchers has conducted first-of-its kind research into how global climate change affects African elephants. The work shows that older elephants will have markedly decreased chances of survival, which will not only drastically reduce the species' overall ability to weather the changing climate but will send ripple effects throughout the surrounding landscape. The team has also modeled possible mitigation scenarios.
Published Discovery of a third RNA virus linage in extreme environments Jan 17, 2024
(via sciencedaily.com) Original source A research group has discovered a novel RNA viral genome from microbes inhabiting a high-temperature acidic hot spring. Their study shows that RNA viruses can live in high-temperature environments (70-80 degrees Celsius), where no RNA viruses have been observed before. In addition to the two known RNA virus kingdoms, a third kingdom may exist.
Published Groundbreaking genome editing tools unlock new possibilities for precision medicine
(via sciencedaily.com) Original source A team of researchers has achieved a major breakthrough in genome editing technology. They've developed a cutting-edge method that combines the power of designer-recombinases with programmable DNA-binding domains to create precise and adaptable genome editing tools.
Published Fungal-rich soil may improve green roofs
(via sciencedaily.com) Original source Green roofs have become increasingly popular thanks to their benefits related to climate adaptation, mitigation, and urban biodiversity management. But, in the U.S., green roofs are typically planted with non-native plants in sterile soils, and their effectiveness declines over time. A new study finds that managing green roof soil microbes boosts healthy urban soil development, which is a methodology that could be applied to support climate resilience in cities.
Published How seahorse-like toxins kill insects
(via sciencedaily.com) Original source Insect-killing bacteria typically release toxins to slay their hosts. The bacterium Photorhabdus luminescens, for example, pumps insect larvae full of the lethal 'Makes caterpillars floppy 1' (Mcf1) toxin, leading them to first become droopy and then dead. However, it has so far been a mystery how Mcf1 unfolds its devastating effect. Researchers successfully used cryo-electron microscopy (cryo-EM) and biochemical assays to characterize the first-ever Mcf1 structure, allowing them to propose a molecular mechanism of the toxin's action. Understanding how bacterial toxins perform their deadly task in such detail is very useful for engineering novel biopesticides, thereby reducing the use of barely specific chemical agents with harmful side effects for the ecosystem.
Published Engineering viruses to kill deadly pathogens
(via sciencedaily.com) Original source Antimicrobial resistance is an urgent and growing global crisis. Researchers are exploring phages, viruses that infect bacteria, as a possible solution. In the new study, researchers successfully modified DNA from four types of phages to kill a deadly pathogen. The process can also be used to produce more phage variants for further exploration.
Published When and how immune cells decide to form pathogen memories
(via sciencedaily.com) Original source During infection, reversible switch permits flexible formation of memory T cells, long-lived blood cells that can remember pathogen encounters and respond upon reinfection.
Published Using computers to design proteins allows researchers to make tunable hydrogels that can form both inside and outside of cells
(via sciencedaily.com) Original source New research demonstrates a new class of hydrogels that can form not just outside cells, but also inside of them. These hydrogels exhibited similar mechanical properties both inside and outside of cells, providing researchers with a new tool to group proteins together inside of cells.
Published Scientists pinpoint growth of brain's cerebellum as key to evolution of bird flight
(via sciencedaily.com) Original source Evolutionary biologists report they have combined PET scans of modern pigeons along with studies of dinosaur fossils to help answer an enduring question in biology: How did the brains of birds evolve to enable them to fly?
Published DNA particles that mimic viruses hold promise as vaccines
(via sciencedaily.com) Original source Using a DNA-based delivery particle, researchers created a vaccine that can induce a strong antibody response against SARS-CoV-2.
Published Asparagus and orchids are more similar than you think
(via sciencedaily.com) Original source How is a beech leaf constructed? What determines the appearance of an asparagus? A new 'encyclopaedia' helps us learn more about the building blocks of plants. The encyclopaedia, probably the largest of its kind, could be used to improve targeted plant breeding efforts, to make them both more climate-resilient and more easily digestible.