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Categories: Biology: General, Mathematics: Puzzles

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Researchers report that they have found a way to get antibacterial drugs through the nearly impenetrable outer membrane of Pseudomonas aeruginosa, a bacterium that -- once it infects a person -- is notoriously difficult to treat.

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Striped skunks are less likely to evolve with their famous and white markings where the threat of predation from mammals is low, scientists have discovered.

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In 2020 and 2021, California experienced fire activity unlike anything recorded in the modern record. When the smoke cleared, the amount of burned forest totaled ten times more than the annual average going back to the late 1800s. We know that wildlife in western forests evolved with changing habitat and disturbances like wildfire. Each species responds differently, some benefiting from openings, others losing critical habitat. What we don't know is how increasing fire severity at large scales is impacting their habitat and survival, because many species are not adapted to these types of 'megafires.'

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A new software tool with enhanced genome-sequencing powers has been developed, increasing the speed and accuracy at which researchers can improve plants through breeding.

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Scientists and colleagues from Utah's caving community have published the first research from their collaborative fieldwork effort deep in Utah's caves. The journal's feature article reveals why caves make such compelling research archives; what was uncovered in Boomerang Cave in northern Utah; why skeletal remains provide new access to hard-to-get data from the recent past; and offers a new zoological baseline for mammalian changes in an alpine community.  

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When bacteria build communities, they cooperate and share nutrients across generations. Researchers have been able to demonstrate this for the first time using a newly developed method. This innovative technique enables the tracking of gene expression during the development of bacterial communities over space and time.

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Some enzymes, such as the one derived from fungi and investigated in this study, are able to produce valuable substances such as the fragrance (R)-1-phenylethanol. To this end, they convert a less expensive substrate using a co-substrate. A research team came up with the idea of supplying them with this co-substrate using a plasma -- a somewhat crazy idea, as plasmas generally have a destructive effect on biomolecules. However, by employing several tricks, the researchers did indeed succeed. They have now refined one of these tricks and thus improved the process: They attach the enzymes to tiny beads in order to hold them in place at the bottom of the reactor, where they are protected from the damaging effects of the plasma.

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Ten newly discovered species of trilobites, hidden for 490 million years in a little-studied part of Thailand, could be the missing pieces in an intricate puzzle of ancient world geography.

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LUCA, the 'last universal common ancestor' of all living organisms, lived 4.32 to at most 4.52 billion years ago. What LUCA looked like is unknown, but it must have been a cell with among others ribosomal proteins and an ATP synthase.

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Researchers have used laser-powered ‘optical tweezers’ to reveal a universal motor mechanism used by viruses for packaging their DNA into infectious particles.

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Scientists have identified the genes in the probiotic Bifidobacteria longum responsible for improving gut motility. A research team found that B. longum strains possessing the abfA cluster of genes can ameliorate constipation through enhanced utilization of an indigestible fiber called arabinan in the gut.

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According to data in mice, extra tryptophan could reduce the risk of future colitis flares.

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A new analysis sheds light on the molecular processes involved when a carnivorous species of fungus known as Arthrobotrys oligospora senses, traps and consumes a worm.

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Scientists have discovered that bacteria can create something like memories about when to form strategies that can cause dangerous infections in people, such as resistance to antibiotics and bacterial swarms when millions of bacteria come together on a single surface. The discovery -- which has potential applications for preventing and combatting bacterial infections and addressing antibiotic-resistant bacteria -- relates to a common chemical element bacterial cells can use to form and pass along these memories to their progeny over later generations.  

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A team of researchers found that caffeic-acid based Carbon Quantum Dots (CACQDs), which can be derived from spent coffee grounds, have the potential to protect brain cells from the damage caused by several neurodegenerative diseases.

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Concerted action is required to mitigate the impact of warming on polar ecosystems and sustainably manage these unique habitats.  

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Malaria is one of the most widespread and deadly infectious diseases worldwide. New compounds are continuously required due to the risk of malaria parasites becoming resistant to the medicines currently used. A team of researchers has now combined the anti-malaria drug artemisinin with coumarin, which, like artemisinin, is also found in plants, and developed an auto-fluorescent compound from both bioactive substances.

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Researchers think that a flavanol found naturally in red wines can interfere with the proper metabolism of alcohol and can lead to a headache.

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Biological materials are made of individual components, including tiny motors that convert fuel into motion. This creates patterns of movement, and the material shapes itself with coherent flows by constant consumption of energy. Such continuously driven materials are called 'active matter'. The mechanics of cells and tissues can be described by active matter theory, a scientific framework to understand shape, flows, and form of living materials. The active matter theory consists of many challenging mathematical equations. Scientists have now developed an algorithm, implemented in an open-source supercomputer code, that can for the first time solve the equations of active matter theory in realistic scenarios. These solutions bring us a big step closer to solving the century-old riddle of how cells and tissues attain their shape and to designing artificial biological machines.

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Researchers have determined the gene mutation responsible for an observable trait in bison -- albinism.