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Categories: Biology: General, Ecology: Research

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Concerted action is required to mitigate the impact of warming on polar ecosystems and sustainably manage these unique habitats.  

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Malaria is one of the most widespread and deadly infectious diseases worldwide. New compounds are continuously required due to the risk of malaria parasites becoming resistant to the medicines currently used. A team of researchers has now combined the anti-malaria drug artemisinin with coumarin, which, like artemisinin, is also found in plants, and developed an auto-fluorescent compound from both bioactive substances.

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Researchers think that a flavanol found naturally in red wines can interfere with the proper metabolism of alcohol and can lead to a headache.

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Biological materials are made of individual components, including tiny motors that convert fuel into motion. This creates patterns of movement, and the material shapes itself with coherent flows by constant consumption of energy. Such continuously driven materials are called 'active matter'. The mechanics of cells and tissues can be described by active matter theory, a scientific framework to understand shape, flows, and form of living materials. The active matter theory consists of many challenging mathematical equations. Scientists have now developed an algorithm, implemented in an open-source supercomputer code, that can for the first time solve the equations of active matter theory in realistic scenarios. These solutions bring us a big step closer to solving the century-old riddle of how cells and tissues attain their shape and to designing artificial biological machines.

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Researchers have determined the gene mutation responsible for an observable trait in bison -- albinism.

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Wild caviar, a pricey delicacy made from sturgeon eggs, has been illegal for decades since poaching brought the fish to the brink of extinction. Today, legal, internationally tradeable caviar can only come from farmed sturgeon, and there are strict regulations in place to help protect the species. However, by conducting genetic and isotope analyses on caviar samples from Bulgaria, Romania, Serbia, and Ukraine -- nations bordering the remaining wild sturgeon populations -- a team of sturgeon experts found evidence that these regulations are actively being broken. Their results show that half of the commercial caviar products they sampled are illegal, and some don't even contain any trace of sturgeon.

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After a massive cyclone transformed the ecosystem of Gorongosa National Park, researchers studied the immediate and knock-on impacts to garner lessons for wildlife managers around the world.

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Researchers have uncovered startling connections between micronutrient deficiencies and the composition of gut microbiomes in early life that could help explain why resistance to antibiotics has been rising across the globe. The team investigated how deficiencies in crucial micronutrients such as vitamin A, B12, folate, iron, and zinc affected the community of bacteria, viruses, fungi and other microbes that live in the digestive system. They discovered that these deficiencies led to significant shifts in the gut microbiome of mice -- most notably an alarming expansion of bacteria and fungi known to be opportunistic pathogens. Importantly, mice with micronutrient deficiencies also exhibited a higher enrichment of genes that have been linked to antibiotic resistance.

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Chemists have developed a bioinspired supramolecular approach to convert photo-switchable molecules from their stable state into metastable one with low-energy red light. Their work enables fast, highly selective, and efficient switching, providing new tools for energy storage, activation of drugs with light, and sensing applications.

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For over 20 years, a research team has studied the common bluetail damselfly. Females occur in three different color forms -- one with a male-like appearance, something that protects them from mating harassment. In a new study, an international research team found that this genetic color variation that is shared between several species arose through changes in a specific genomic region at least five million years ago.

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Unlike humans, zebrafish can completely regenerate their hearts after injury. They owe this ability to the interaction between their nervous and immune systems, as researchers now report.

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CITE-seq (cellular indexing of transcriptomes and epitopes) is an RNA sequencing-based method that simultaneously quantifies cell surface protein and transcriptomic data within a single cell readout. The ability to study cells concurrently offers unprecedented insights into new cell types, disease states or other conditions.   While CITE-seq solves the problem of detecting a limited number of proteins while using single-cell sequencing in an unbiased way, one of its limitations is the high levels of background noise that can hinder analysis.

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Algae living within the soft tissue of coral supply much of the energy needed by their hosts, and some symbiotic algae help coral withstand warmer water better than others. Researchers have now found that there was a tradeoff for corals dominated by the thermally sensitive algae -- they have higher growth, but only in cooler water.

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Nature photographers posting to social media are helping improve biodiversity conservation mapping in South Asia, and the method could go global.

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Researchers have rediscovered and successfully cultivating Rhabdamoeba marina -- a rare marine amoeba that has only been reported in two cases in the past century. Using this culture strain, they performed a comprehensive analysis of its genetic sequence, revealing for the first time the phylogenetic position of this enigmatic amoeba, and proposed a novel taxonomic classification based on their research findings.

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Microbial communities are thought to contain keystone species, which can disproportionately affect the stability of the communities, even if only present in low abundances. Identifying these keystone species can be challenging, especially in the human gut, since it is not feasible to isolate them through systematic elimination. Researchers have designed a new data-driven keystone species identification (DKI) framework that uses machine learning to resolve this difficulty. 

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Researchers have discovered a 'genomic tug of war' in animal studies that could influence how well certain patients -- or certain cancers -- respond to decitabine, a drug used to treat myelodysplastic syndromes that is plagued by drug resistance issues. For the first time, researchers show that decitabine causes coding and non-coding regions of DNA to engage in a tug of war for a gene activator, called H2A.Z. Typically, deticabine draws this gene activator away from coding DNA, causing gene expression to grind to a halt and cells to die. However, many types of cancer have very high levels of H2A.Z, which may help them overcome this decitabine-induced tug of war, allowing the cancer to grow.

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A new theoretical model helps explain how epigenetic memories, encoded in chemical modifications of chromatin, are passed from generation to generation.  Within each cell's nucleus, researchers suggest, the 3D folding patterns of its genome determines which parts of the genome will be marked by these chemical modifications.

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Researchers take a look at data that has so far been mostly discarded as contamination, revealing the previously underestimated role of extracellular vesicles (EVs). These are important for the exchange of genetic information between cells and thus for the microbial community in the sea.

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New research has revealed that bumblebees cannot taste pesticides present in nectar, even at lethal concentrations. This means bumblebees are not able to avoid contaminated nectar, putting them at high risk of pesticide exposure and posing a threat to crop pollination.