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Categories: Biology: General, Paleontology: Climate

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Researchers have discovered a previously unknown ability of a group of immune system cells, known as Atypical B cells (ABCs), to fight infectious diseases such as malaria. The scientists say ABCs could also be key to developing new treatments for chronic autoimmune conditions such as lupus.

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Researchers report the results of the first ever genome-wide association study (GWAS) of a biosafety level 4 (BSL-4) virus. The team found two key human genetic factors that could help explain why some people develop severe Lassa fever, and a set of LARGE1 variants linked to a reduced chance of getting Lassa fever. The work could lay the foundation for better treatments for Lassa fever and other similar diseases. The scientists are already working on a similar genetics study of Ebola susceptibility.

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The Greenland ice sheet lies thousands of miles from North America yet holds clues to the distant continent's environmental history. Nearly two miles thick in places, the ice sheet grows as snow drifts from the sky and builds up over time. But snow isn't the only thing carried in by air currents that swirl around the atmosphere, with microscopic pollen grains and pieces of ash mixing with snowfall and preserving records of the past in the ice. A new study examined these pollen grains and identified how eastern Canada's forests grew, retreated, and changed through time.

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Researchers have uncovered the first direct evidence that the West Antarctic Ice Sheet shrunk suddenly and dramatically at the end of the Last Ice Age, around eight thousand years ago. The evidence, contained within an ice core, shows that in one location the ice sheet thinned by 450 meters -- that's more than the height of the Empire State Building -- in just under 200 years.

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Scientists have discovered a tiny worm species that infects and kills insects. These worms, called nematodes, could control crop pests in warm, humid places where other beneficial nematodes are currently unable to thrive.

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A newly discovered neural circuit mediates between navigational brain cells, acting as a sort of mental steering wheel.

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Researchers have shed new light on the ancient relationship between moss and fungi. They discovered that intricate moss-fungi interactions often depended on a third variable -- the presence of endobacteria within the fungi themselves.

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Researchers have made a groundbreaking discovery: a new cell that remembers allergies.

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Inspired during field work in South Australia's Flinders Ranges, geoscientists have proposed that all-time low volcanic carbon dioxide emissions triggered a 57-million-year-long global 'Sturtian' ice age.

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Over the past 15 years, researchers have identified hundreds of regions in the human genome associated with heart attack risk. However, researchers lack efficient ways to explore how these genetic variants are molecularly connected to cardiovascular disease, limiting efforts to develop therapeutics. To streamline analysis of hundreds of genetic variants associated with coronary artery disease (CAD), a team of researchers combined multiple sequencing and experimental techniques to map the relationship between known CAD variants and the biological pathways they impact.

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Researchers say hydroquinine could be an effective naturally occurring disinfecting solution for contact lenses and help combat keratitis infections.

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The ability to detect diseases at an early stage or even predict their onset would be of tremendous benefit to doctors and patients alike. A research team now develops intelligent, miniaturized biosensor devices and systems using nanomaterials to determine biomolecules and cells as well as biochemical reactions or processes as disease markers. The team's current publication describes the development of a portable, palm-sized test system that can simultaneously carry out up to thirty-two analyses of one sample.

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Bacteria in the mouth may play a role in survival from idiopathic pulmonary fibrosis (IPF), finds a new study.

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Researchers have identified a new approach to controlling bacterial infections. The team found a way to turn on a vital bacterial defense mechanism to fight and manage bacterial infections. The defense system, called cyclic oligonucleotide-based antiphage signaling system (CBASS), is a natural mechanism used by certain bacteria to protect themselves from viral attacks. Bacteria self-destruct as a means to prevent the spread of virus to other bacterial cells in the population.

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A team of researchers recently published a pioneering study that answers a central question in biology: how do organisms rally a wide range of cellular processes when they encounter a change -- either internally or in the external environment -- to thrive in good times or survive the bad times? The research, focused on plants, identifies the interactions between four compounds: pectin, receptor proteins FERONIA and LLG1 and the signal RALF peptide.

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Extreme events wipe out entire forests, dramatically eliminating complex ecosystems as well as local communities. Researchers have become quite familiar with such attention-grabbing events over the years. They know less, however, about the more common moderate-severity disturbances, such as relatively small fires, ice storms, and outbreaks of pests or pathogens.

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A research group explored how the social evolution of microbes can be manipulated by tuning the physical parameters of the environment in which they live.

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Researchers have developed a new biocontainment method for limiting the escape of genetically engineered organisms used in industrial processes.

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Researchers studied in detail the strange protist Meteora sporadica, which swings its two lateral arms back and forth. The results of the study indicated that M. sporadica has a complex cytoskeleton that is closely related to Hemimastigophora, a group of organisms considered to be one of the deepest branches of eukaryotes.

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Researchers have discovered peptide factors that function in the shoot and root systems to transport iron into the root nodules colonized by nitrogen-fixing bacteria. Moreover, these peptide factors regulate nitrogen homeostasis by maintaining a balance between nitrogen and iron concentrations in plants without rhizobial symbiosis.