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Categories: Biology: General, Chemistry: Biochemistry
Published Enzyme-powered 'snot bots' help deliver drugs in sticky situations
(via sciencedaily.com) Original source Snot might not be the first place you'd expect nanobots to be swimming around. But this slimy secretion exists in more places than just your nose and piles of dirty tissues -- it also lines and helps protect the lungs, stomach, intestines and eyes. And now, researchers have demonstrated in mice that their tiny, enzyme-powered 'snot bots' can push through the defensive, sticky layer and potentially deliver drugs more efficiently.
Published A new addition to the CRISPR toolbox: Teaching the gene scissors to detect RNA
(via sciencedaily.com) Original source CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers have now expanded this extensive toolbox further. Their novel method, called PUMA, enables the detection of RNA with Cas12 nucleases, which naturally target DNA. PUMA promises a wide range of applications and high accuracy.
Published Scientists use machine learning to predict diversity of tree species in forests
(via sciencedaily.com) Original source Researchers used machine learning to generate highly detailed maps of over 100 million individual trees from 24 sites across the U.S. These maps provide information about individual tree species and conditions, which can greatly aid conservation efforts and other ecological projects.
Published Transporting precious cargo using the body's own delivery system
(via sciencedaily.com) Original source Delivery systems in body continuously move materials between cells. Hijacking these systems allowed scientists to improve loading and delivery of therapeutic proteins. Biophysical principles could be used to enable more cost-effective loading of biological cargo into cell-derived delivery systems. Engineered molecules loaded up to 240 times more protein than other loading methods.
Published Unique characteristics of previously unexplored protein discovered
(via sciencedaily.com) Original source Research achieves scientific breakthrough in understanding cell division.
Published Immune system in the spotlight
(via sciencedaily.com) Original source Our immune system is always on alert, detecting and eliminating pathogens and cancer cells. Cellular control mechanisms cause diseased cells to present antigens on their surface like signs for the immune system. For analysis of the necessary complex antigen processing and transport processes in real time, researchers have developed a 'cage' that is opened with light to release trapped antigens at a specific place and time.
Published Food aroma study may help explain why meals taste bad in space
(via sciencedaily.com) Original source A new study on common food aromas may help explain why astronauts report that meals taste bland in space and struggle to eat their normal nutritional intake. This research has broader implications for improving the diets of isolated people, including nursing home residents, by personalizing aromas to enhance the flavor of their food.
Published Ancient microbes offer clues to how complex life evolved
(via sciencedaily.com) Original source Researchers have discovered that a single-celled organism, a close relative of animals, harbors the remnants of ancient giant viruses woven into its own genetic code. This finding sheds light on how complex organisms may have acquired some of their genes and highlights the dynamic interplay between viruses and their hosts.
Published Capturing carbon with energy-efficient sodium carbonate-nanocarbon hybrid material
(via sciencedaily.com) Original source Carbon capture is a promising approach for mitigating carbon dioxide (CO2) emissions. Different materials have been used to capture CO2 from industrial exhaust gases. Scientists developed hybrid CO2 capture materials containing sodium carbonate and nanocarbon prepared at different temperatures, tested their performance, and identified the optimal calcination temperature condition. They found that the hybrid material exhibits and maintains high CO2 capture capacity for multiple regeneration cycles at a lower temperature, making it cost- and energy-effective.
Published Harnessing big data helps scientists home in on new antimicrobials
(via sciencedaily.com) Original source Researchers have developed a strategy to identify new antimicrobial drugs with therapeutic promise from bacterial datasets, providing clues for discovering alternatives to traditional antibiotics.
Published Oil and natural gas development in Permian is a key source of ozone pollution in Carlsbad Caverns National Park, study finds
(via sciencedaily.com) Original source New research shows that ozone concentrations at Carlsbad Caverns National Park frequently exceed Environmental Protection Agency health standards, likely due to oil and natural gas development in the Permian Basin and surrounding region.
Published E. coli variant may cause antimicrobial resistance in dogs, humans
(via sciencedaily.com) Original source Researchers studying antimicrobial-resistant E. coli -- the leading cause of human death due to antimicrobial resistance worldwide -- have identified a mechanism in dogs that may render multiple antibiotic classes ineffective.
Published Local dragonflies expose mercury pollution patterns
(via sciencedaily.com) Original source A new study has unveiled surprising findings about mercury pollution: where it comes from and how it moves through the environment vary significantly depending on the ecosystem. In drier regions, most mercury is deposited through rain and snow. In wetter, forested areas, gaseous mercury from the air sticks to leaves, which then fall and carry the toxin into the ground.
Published Researchers find that frogs can quickly increase their tolerance to pesticides
(via sciencedaily.com) Original source Although there is a large body of research on pests evolving tolerances for the pesticides meant to destroy them, there have been considerably fewer studies on how non-target animals in these ecosystems may do the same.
Published Unlocking the mystery of preexisting drug resistance: New study sheds light on cancer evolution
(via sciencedaily.com) Original source The evolution of resistance to diseases, from infectious illnesses to cancers, poses a formidable challenge. Despite the expectation that resistance-conferring mutations would dwindle in the absence of treatment due to a reduced growth rate, preexisting resistance is pervasive across diseases that evolve -- like cancer and pathogens -- defying conventional wisdom.
Published Loss of oxygen in lakes and oceans a major threat to ecosystems, society, and planet
(via sciencedaily.com) Original source Oxygen is a fundamental requirement of life, and the loss of oxygen in water, referred to as aquatic deoxygenation, is a threat to life at all levels. In fact, researchers describe how ongoing deoxygenation presents a major threat to the stability of the planet as a whole.
Published Building a roadmap to bioengineer plants that produce their own nitrogen fertilizer
(via sciencedaily.com) Original source Nitrogen fertilizers make it possible to feed the world's growing population, but they are also costly adn harm ecosystems. However, a few plants have evolved the ability to acquire their own nitrogen with the help of bacteria, and a new study helps explain how they did it, not once, but multiple times.
Published Receptors make dairy cows a prime target for influenza
(via sciencedaily.com) Original source A study helps explain why dairy cows infected by highly pathogenic avian influenza are shedding the virus in their milk. Their findings could help develop biosecurity measures aimed at slowing the spread of the illness.
Published Crystals from radioactive metal actinium
(via sciencedaily.com) Original source Researchers grew crystals containing actinium and illuminated them with X-rays to learn how the radioactive metal binds with other elements. That information could help design better cancer treatments.
Published Big boost for new epigenetics paradigm: CoRSIVs, first discovered in humans, now found in cattle
(via sciencedaily.com) Original source A study opens new possibilities to improve production efficiency in the cattle industry and potentially animal agriculture more broadly.