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Categories: Biology: General, Chemistry: Biochemistry
Published New approach to Epstein-Barr virus and resulting diseases
(via sciencedaily.com) Original source The Epstein-Barr virus can cause a spectrum of diseases, including a range of cancers. Emerging data now show that inhibition of a specific metabolic pathway in infected cells can diminish latent infection and therefore the risk of downstream disease.
Published Psychedelic drug-induced hyperconnectivity in the brain helps clarify altered subjective experiences
(via sciencedaily.com) Original source A new study shows that the use of psilocybin, a compound found in the widely known 'magic mushrooms,' initiates a pattern of hyperconnectivity in the brain linked to the ego-modifying effects and feelings of oceanic boundlessness. The findings help explain the so-called mystical experiences people report during the use of psychedelics and are pertinent to the psychotherapeutic applications of psychedelic drugs to treat psychiatric disorders such as depression.
Published New 'atlas' provides unprecedented insights on how genes function in early embryo development
(via sciencedaily.com) Original source Biologists have provided new insights on a longstanding puzzle in biology: How complex organisms arise from a single fertilized cell. Producing a new 'gene atlas' with 4-D imaging, the researchers captured unprecedented insights on how embryonic development unfolds.
Published Designing a better nest to help endangered turtles
(via sciencedaily.com) Original source With Ontario's eight species of turtles considered at risk, a new nest designed by researchers has the potential to significantly bolster their struggling populations. The habitat is the first designed for turtles in rock barren landscapes, such as the research site around Georgian Bay. It uses moss and lichen. The researchers found that the design provided a more stable environment for incubating eggs compared to natural sites, where the probability of an egg hatching was only 10 per cent compared to 41 per cent in the created site.
Published Charting a pathway to next-gen biofuels
(via sciencedaily.com) Original source From soil to sequestration, researchers have modeled what a supply chain for second-generation biofuels might look like in the midwestern United States.
Published Birdsong and human voice built from same genetic blueprint
(via sciencedaily.com) Original source Humans have been long fascinated by bird song and the cacophony of other avian sounds -- from coos and honks to quacks and peeps. But little is known about how the unique vocal organ of birds -- the syrinx -- varies from species to species or its deeper evolutionary origins. A trio of recent studies is changing that. The studies include high-resolution anatomical scans of syrinxes from hummingbirds and ostriches -- the world's smallest and largest bird species -- and the discovery that the syrinx and larynx, the vocal organ of reptiles and mammals, including humans, share the same developmental programming.
Published Mistaken identity cleared up of foodborne pathogen causing severe symptoms in children
(via sciencedaily.com) Original source Researchers have developed a quantitative real-time PCR-based detection method for the emerging zoonotic organism Escherichia albertii. They found that E. albertii survives in the human intestinal tract for about four weeks at least.
Published Team enhances stereotactic neurosurgery precision using MRI-guided multi-stage robotic positioner
(via sciencedaily.com) Original source A research team developed an interactive multi-stage robotic positioner specifically designed for magnetic resonance imaging (MRI)-guided stereotactic neurosurgery.
Published Novel approach to interrogate tissue-specific protein-protein interactions
(via sciencedaily.com) Original source Multicellular organisms, like animals and plants, have complex cells with diverse functions. This complexity arises from the need for cells to produce distinct proteins that interact with each other. This interaction is crucial for cells to carry out their specific tasks and to form complex molecular machinery. However, our current understanding of such protein-protein interactions often lacks cellular contexts because they were usually studied in an in vitro system or in cells isolated from their tissue environment. Effective methods to investigate protein-protein interactions in a tissue-specific manner are largely missing.
Published Producing novel liquid crystals by stacking antiaromatic units
(via sciencedaily.com) Original source In a recent study, researchers developed modified norcorrole molecules whose side chains favored the formation of columnar -stacking structures. Using these compounds, they produced liquid crystals with high electrical conductivity and thermotropic properties. Their findings open up new design avenues for materials useful in electronics, sensing, optics, and biomedicine.
Published Tracking down the genetic causes of lupus to personalize treatment
(via sciencedaily.com) Original source Treatment of autoimmune diseases like lupus has long relied on steroids to knock down the immune system, but more targeted therapies are currently undergoing clinical trials. To make sure these therapies get to the patients who will benefit, work is needed to identify the specific mutations behind each patient's disease. Researchers now report several dozen mutations associated with oversensitive toll-like receptors -- a major cause of autoimmune disease -- and linked two mutations to patients.
Published Sexual parasitism helped anglerfish invade the deep sea during a time of global warming
(via sciencedaily.com) Original source Members of the vertebrate group including anglerfishes are unique in possessing a characteristic known as sexual parasitism, in which males temporarily attach or permanently fuse with females to mate. Now, researchers show that sexual parasitism arose during a time of major global warming and rapid transition for anglerfishes from the ocean floor to the deep, open sea.
Published Wearable devices get signal boost from innovative material
(via sciencedaily.com) Original source An international team have developed a new material that moves like skin while preserving signal strength in electronics. The technology could enable the development of next-generation wearable devices with continuous, consistent wireless and battery-free functionality.
Published Wearable ultrasound patch enables continuous, non-invasive monitoring of cerebral blood flow
(via sciencedaily.com) Original source Engineers have developed a wearable ultrasound patch that can offer continuous, non-invasive monitoring of blood flow in the brain. The soft and stretchy patch can be comfortably worn on the temple to provide three-dimensional data on cerebral blood flow--a first in wearable technology.
Published Scientists learn how to control muscles with light
(via sciencedaily.com) Original source Researchers developed a way to help people with amputation or paralysis regain limb control. Their optogenetic technique could offer more precise control over muscle contraction, along with a dramatic decrease in muscle fatigue.
Published Community science volunteers can set scientific world abuzz with new bumble bee sightings
(via sciencedaily.com) Original source Community science volunteers -- laypeople with an interest in bees and conservation -- significantly contribute to the scientific knowledge of native bumble bees across Canada and the United States. It's buzz worthy confirmation that community science programs can play an important role in monitoring the changing distributions of bumble bees and more.
Published Exploring diversity in cell division
(via sciencedaily.com) Original source Animals and fungi predominantly use two different modes of cell division -- called open and closed mitosis, respectively. A new study has shown that different species of Ichthyosporea -- marine protists that are close relatives of both animals and fungi -- use either open and closed mitosis, closely correlated to whether the species has multinucleate life cycle stages. The study demonstrates the way animals do cell division might have evolved long before animals themselves did and how this is linked to an organism's life cycle.
Published Sweet move: a modified sugar enhances antisense oligonucleotide safety and efficacy
(via sciencedaily.com) Original source Researchers found that adding a newly developed modified sugar, BNAP-AEO, to gapmer antisense oligonucleotides (ASOs) increased their affinity for target RNAs, thus significantly enhancing their gene-silencing effects in vitro and in vivo. The BNAP-AEO modification also decreased gapmer ASO toxicity to the central nervous system (CNS), suggesting that it could improve the clinical application of ASO treatment of CNS disease.
Published Australian study proves 'humans are planet's most frightening predator'
(via sciencedaily.com) Original source A new study demonstrates that kangaroos, wallabies and other Australian marsupials fear humans far more than any other predator.
Published Researchers design new metal-free porous framework materials
(via sciencedaily.com) Original source Researchers have used computational design methods to develop non-metal organic porous framework materials, with potential applications in areas such as catalysis, water capture or hydrogen storage.