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Biology: Biochemistry Biology: Cell Biology Biology: Developmental Biology: General Chemistry: Biochemistry
Published

CRISPR-based genome editing in Nile grass rats      (via sciencedaily.com)     Original source 

A team of researchers has discovered a set of methods that enabled the first successful CRISPR-based genome editing in Nile grass rats.

Biology: Biochemistry Biology: Cell Biology Biology: General
Published

Bioengineers develop lotus leaf-inspired system to advance study of cancer cell clusters      (via sciencedaily.com)     Original source 

Bioengineers have harnessed the lotus effect to develop a system for culturing cancer cell clusters that can shed light on hard-to-study tumor properties. The new zinc oxide-based culturing surface mimics the lotus leaf surface structure, providing a highly tunable platform for the high-throughput generation of three-dimensional nanoscale tumor models.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Molecular
Published

Strength training activates cellular waste disposal      (via sciencedaily.com)     Original source 

The elimination of damaged cell components is essential for the maintenance of the body's tissues and organs. An international research team has made significant findings on mechanisms for the clearing of cellular wastes, showing that strength training activates such mechanisms. The findings could form the basis for new therapies for heart failure and nerve diseases, and even afford benefits for manned space missions.

Biology: Biochemistry Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Ecology: Endangered Species Offbeat: Earth and Climate Offbeat: General Offbeat: Plants and Animals
Published

Innovative field experiments shed light on biological clocks in nature      (via sciencedaily.com)     Original source 

A new study has used a series of innovative field experiments to show how plants combine circadian clock signals with environmental cues under naturally fluctuating conditions.

Biology: Cell Biology Biology: General Biology: Microbiology
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Chlamydia can settle in the intestine      (via sciencedaily.com)     Original source 

Chlamydiae are sexually transmitted pathogens that can apparently survive in the human gut for a long time.

Biology: Biochemistry Biology: Evolutionary Biology: General Offbeat: General Offbeat: Plants and Animals
Published

Colorful traits in primates ease tensions between groups      (via sciencedaily.com)     Original source 

Primate ornamentation plays a crucial role in communication not only within social groups but also between them, according to a new study. The research reveals that the males of species with overlapping home ranges often display vibrant colors or elaborate features, traits that may help reduce intergroup aggression by enabling quick assessments of potential rivals.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Revealing DNA behavior in record time      (via sciencedaily.com)     Original source 

Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process. Biophysicists have developed a technique that speeds up screening of individual DNA molecules at least a thousand times. With this technology, they can measure millions of DNA molecules within a week instead of years to decades.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Microbiology Biology: Zoology Environmental: Water Offbeat: Earth and Climate Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals
Published

Creature the size of a dust grain found hiding in California's Mono Lake      (via sciencedaily.com)     Original source 

Mono Lake is a beautiful but harsh environment, its salty and arsenic-laced water home to brine shrimp, alkali flies and little else. Scientists recently discovered an unsuspected resident, however, a microscopic creature -- a choanoflagelatte -- that forms colonies that harbor their own unique bacterial microbiomes. The creature, part of the sister group to all animals, could shed light on the evolution of animals' intimate interactions with bacteria and the rise of multicellular life.

Biology: Biochemistry Biology: Developmental Biology: General
Published

T cells manipulate the memory of innate immune cells      (via sciencedaily.com)     Original source 

Research reveals that T cells from the adaptive immune system can manipulate the memory of innate immune cells. Previously, it was believed that the memory of innate immune cells operated independently. This surprising connection opens up new possibilities for the treatment of various diseases. A mouse model shows that no immunosuppressive drugs are needed after an organ transplantation if this interaction between T cells and the innate immunity is temporarily blocked after the transplantation.

Biology: Biochemistry Biology: Evolutionary Biology: General Ecology: Invasive Species Ecology: Nature
Published

From pets to pests: How domestic rabbits survive the wilderness      (via sciencedaily.com)     Original source 

How do rabbits go from fluffy pets to marauding invaders? Rabbits have colonized countries worldwide, often with dire economic and ecological consequences, but their secret has until now been a mystery. Biologists sequenced the genomes of nearly 300 rabbits from across three continents to unveil the key genetic changes that make these animals master colonizers.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

Gut molecule slows fat burning during fasting      (via sciencedaily.com)     Original source 

In a struggle that probably sounds familiar to dieters everywhere, the less a Caenorhabditis elegans (C. elegans) worm eats, the more slowly it loses fat. Now, scientists have discovered why: a small molecule produced by the worms' intestines during fasting travels to the brain to block a fat-burning signal during this time.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Ecology: Trees
Published

Next time you beat a virus, thank your microbial ancestors      (via sciencedaily.com)     Original source 

When you get infected with a virus, some of the first weapons your body deploys to fight it were passed down to us from our microbial ancestors billions of years ago. According to new research, two key elements of our innate immune system came from a group of microbes called Asgard archaea.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Environmental: General Environmental: Water Geoscience: Geochemistry
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Life from a drop of rain: New research suggests rainwater helped form the first protocell walls      (via sciencedaily.com)     Original source 

New research shows that rainwater could have helped create a meshy wall around protocells 3.8 billion years ago, a critical step in the transition from tiny beads of RNA to every bacterium, plant, animal, and human that ever lived.

Biology: Biochemistry Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics
Published

Survival tactics: AI-driven insights into chromatin changes for winter dormancy in axillary buds      (via sciencedaily.com)     Original source 

Epigenetics confers a survival advantage in plants to endure harsh weather by inducing bud dormancy. Environmental factors or intrinsic signals trigger the transition between growth and dormancy. Researchers explore the role of chromatin and transcriptional changes in the bud and further analyze data using artificial intelligence models. The findings of this study highlight epigenetic strategies to overcome the effects of short winters during global warming for plant survival.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology
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'DNA scavengers' can stop some antibiotic resistance from spreading      (via sciencedaily.com)     Original source 

For nearly a century, scientists have waged war on antibiotic-resistant microbes. Researchers say they've found a new way to prevent it -- by unleashing 'DNA scavengers' in wastewater treatment plants.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: General Chemistry: Inorganic Chemistry Geoscience: Geochemistry
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Engineered Bacteria make thermally stable plastics similar to polystyrene and PET      (via sciencedaily.com)     Original source 

Bioengineers around the world have been working to create plastic-producing microbes that could replace the petroleum-based plastics industry. Now, researchers have overcome a major hurdle: getting bacteria to produce polymers that contain ring-like structures, which make the plastics more rigid and thermally stable. Because these molecules are usually toxic to microorganisms, the researchers had to construct a novel metabolic pathway that would enable the E. coli bacteria to both produce and tolerate the accumulation of the polymer and the building blocks it is composed of. The resulting polymer is biodegradable and has physical properties that could lend it to biomedical applications such as drug delivery, though more research is needed.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Benefits and downside of fasting      (via sciencedaily.com)     Original source 

Researchers identified a signaling pathway in mice that boosts intestinal stem cells' regeneration abilities after fasting. When cancerous mutations occurred during this regenerative period, mice were more likely to develop early-stage intestinal tumors.