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Categories: Biology: General
Published Self-repairing mitochondria use novel recycling system
(via sciencedaily.com) Original source A newly identified identified cellular mechanism allows mitochondria to recycle localized damage and maintain healthy function.
Published Surprising mechanism for removing dead cells identified
(via sciencedaily.com) Original source A tandem signaling process turns ordinary cells into an efficient cleanup crew.
Published Compound in rosemary extract can reduce cocaine sensitivity
(via sciencedaily.com) Original source A team of researchers has discovered that an antioxidant found in rosemary extract can reduce volitional intakes of cocaine by moderating the brain's reward response, offering a new therapeutic target for treating addiction.
Published Researchers teaching artificial intelligence about frustration in protein folding
(via sciencedaily.com) Original source Scientists have found a new way to predict how proteins change their shape when they function, which is important for understanding how they work in living systems. While recent artificial intelligence (AI) technology has made it possible to predict what proteins look like in their resting state, figuring out how they move is still challenging because there is not enough direct data from experiments on protein motions to train the neural networks.
Published Gut bioelectricity provides a path for 'bad' bacteria to cause diseases
(via sciencedaily.com) Original source Researchers have discovered a novel bioelectrical mechanism that pathogens like Salmonella use to find entry points in the gut lining that would allow pathogens to pass and cause infection.
Published Humpbacks are among animals who manufacture and wield tools
(via sciencedaily.com) Original source Researchers suggest a new designation of the humpback whales they study: tool wielders. Researchers have known that humpback whales create "bubble-nets" to hunt, but they have learned that the animals don't just create the bubble-nets; they manipulate this unique tool in a variety of ways to maximize their food intake in Alaskan feeding grounds.
Published Hospital bacteria tracked better than ever before with new technique
(via sciencedaily.com) Original source New method provides high-resolution surveillance data about multiple common antibiotic-resistant bacteria at once and could help prevent the spread of infections.
Published Mother's gut microbiome during pregnancy shapes baby's brain development
(via sciencedaily.com) Original source A study in mice has found that the bacteria Bifidobacterium breve in the mother's gut during pregnancy supports healthy brain development in the fetus.
Published How early-life antibiotics turn immunity into allergy
(via sciencedaily.com) Original source Researchers have shown how and why the depletion of microbes in a newborn's gut by antibiotics can lead to lifelong respiratory allergies. The research team identified a specific cascade of events that lead to allergies and asthma, opening many new avenues for exploring potential preventions and treatments.
Published 'Masters of shape-shifting': How darkling beetles conquered the world
(via sciencedaily.com) Original source Large-scale genomic analysis of darkling beetles, a hyper-diverse insect group of more than 30,000 species worldwide, rolls back the curtain on a 150-million-year evolutionary tale of one of Earth's most ecologically important yet inconspicuous creatures, according to new research.
Published New worm study paves way for better RNA-based drugs to treat human disease
(via sciencedaily.com) Original source Researchers have discovered RNA mechanisms that may lead to more effective, durable and targeted treatments for conditions like high cholesterol, liver diseases and cancers.
Published Deadly sea snail toxin could be key to making better medicines
(via sciencedaily.com) Original source Scientists are finding clues for how to treat diabetes and hormone disorders in an unexpected place: a toxin from one of the most venomous animals on the planet.
Published 'Molecular compass' points way to reduction of animal testing
(via sciencedaily.com) Original source Machine learning models have become increasingly popular for risk assessment of chemical compounds. However, they are often considered 'black boxes' due to their lack of transparency. To increase confidence in these models, researchers proposed carefully identifying the areas of chemical space where these models are weak. They developed an innovative software tool for this purpose, and the results of this research approach have just been published.
Published Scientists discover new code governing gene activity
(via sciencedaily.com) Original source A newly discovered code within DNA -- coined 'spatial grammar' -- holds a key to understanding how gene activity is encoded in the human genome. This breakthrough finding revealed a long-postulated hidden spatial grammar embedded in DNA. The research could reshape scientists' understanding of gene regulation and how genetic variations may influence gene expression in development or disease.
Published Researchers uncover the secrets of 'plant puberty'
(via sciencedaily.com) Original source Researchers have identified the genetic changes linked to why plants go through a developmental change similar to 'puberty' at different rates, a discovery which could lead to better crop nutrition.
Published Gut microbial pathway identified as target for improved heart disease treatment
(via sciencedaily.com) Original source Researchers have made a significant discovery about how the gut microbiome interacts with cells to cause cardiovascular disease. The study found phenylacetylglutamine (PAG), produced by gut bacteria as a waste product, then absorbed and formed in the liver, interacts with previously undiscovered locations on beta-2 adrenergic receptors on heart cells once it enters the circulation.
Published Peering into the mind of artificial intelligence to make better antibiotics
(via sciencedaily.com) Original source Artificial intelligence (AI) has exploded in popularity as of late. But just like a human, it's hard to read an AI model's mind. Explainable AI (XAI) could help us do just that by providing justification for a model's decisions. And now, researchers are using XAI to scrutinize predictive AI models more closely, which could help make better antibiotics.
Published Key biofuel-producing microalga believed to be a single species is actually three
(via sciencedaily.com) Original source When a global pandemic forced previous a graduate student out of the lab and onto the computer, he found a world of difference hidden in the long-studied species of Botryoccocus braunii -- and discovered that it isn't one species at all, but three.
Published New insights on how bird flu crosses the species barrier
(via sciencedaily.com) Original source The avian influenza virus needs to mutate to cross the species barrier and to infect and replicate within mammalian cells. Scientists have now deciphered the structure of the avian influenza virus's polymerase when it interacts with a human protein essential for the virus to replicate within the cell. The structure of this replication complex provides important information about the mutations that avian influenza polymerase must undergo to adapt to mammals, including humans. These results can help scientists monitor the evolution and adaptability of bird flu strains, such as H5N1 or H7N9, towards infecting other species.
Published Searching old stem cells that stay young forever
(via sciencedaily.com) Original source The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists have now identified possible candidates for multipotent stem cells in the sea anemone for the first time. These stem cells are regulated by evolutionary highly conserved genes.