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Categories: Biology: Developmental, Chemistry: Thermodynamics

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Researchers have discovered that phenylbutazone, a non-steroidal anti-inflammatory drug (NSAID) commonly prescribed in horses, can affect the ability of a mare's egg cells -- called 'oocytes' -- to become viable embryos, which is a crucial step in assisted reproduction in horses.

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A new technique for mechanically manipulating stem cells could lead to new stem cell treatments, which have yet to fulfill their therapeutic potential.

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A study has shown that different plant species tackle the same evolutionary hurdle in different ways, and the findings may give insight into aggressive forms of cancer.

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A new study has rewritten the conventionally understood evolutionary history of certain ion channels -- proteins critical for electrical signaling in the nervous system. The study shows that the Shaker family of ion channels were present in microscopic single cell organisms well before the common ancestor of all animals and thus before the origin of the nervous system.

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Cell-cell adhesion-induced patterning in keratinocytes can be explained by just starvation and strong adhesion researchers find.

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A previously unknown mechanism of active matter self-organization essential for bacterial cell division follows the motto 'dying to align': Misaligned filaments 'die' spontaneously to form a ring structure at the center of the dividing cell. The work could find applications in developing synthetic self-healing materials.

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A key question that remains in biology and biophysics is how three-dimensional tissue shapes emerge during animal development. Research teams have now found a mechanism by which tissues can be 'programmed' to transition from a flat state to a three-dimensional shape.

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The movement of radiant heat -- felt when a hot surface warms our bodies and homes -- between buildings and their surroundings at ground level makes buildings with less skyward-facing surfaces harder to cool. A research team has demonstrated a new passive cooling technology that coats walls and windows with materials that can better manage heat movement between buildings and their surroundings at ground level. Findings could reduce the reliance on air conditioning and provide a more environmentally friendly, low-cost and scalable option for low-income communities with limited or no access to cooling and heating systems.

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A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and revealing a potential wellspring of material for new genetic therapies.

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The key finding was that temperature and genome size, not body size, had the greatest influence on the maximum population growth rate of the diatoms. Yet body size still mattered in colder latitudes, conserving Bermann's Rule.

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Researchers invented a technique that uses a specialized light projector and a photosensitive chemical additive to imprint two- and three-dimensional images inside any polymer. The light-based engraving remains in the polymer until heat or light are applied, which erases the image and makes it ready to use again. The technology is intended for any situation where having detailed, precise visual data in a compact and easily customizable format could be critical, such as planning surgeries and developing architectural designs.

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A viral defense mechanism can be used to accelerate the creation of female stem cell lines in mice. The findings can boost efforts in medical research, drug testing, and regenerative therapies, particularly for women and individuals with two X chromosomes.

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In nematodes and humans, mitochondrial stress in the nervous system initiates a whole-body response that is most pronounced in the gut. A recent study showed that in nematodes, the odor of a pathogen triggers the nervous system to broadcast this response to the rest of the organism, prepping mitochondria in intestinal cells to fight a bacterial infection. Humans, too, may be able to sense pathogenic odors that prepare the gut for an infection.

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Heat and pressure can deteriorate the properties of piezoelectric materials that make state-of-the-art ultrasound and sonar technologies possible -- and fixing that damage has historically required disassembling devices and exposing the materials to even higher temperatures. Now researchers have developed a technique to restore those properties at room temperature, making it easier to repair these devices -- and paving the way for new ultrasound technologies.

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Can plasma be sufficiently heated inside a tokamak using only microwaves? New research suggests it can! Eliminating the central ohmic heating coil normally used in tokamaks will free up much-needed space for a more compact, efficient spherical tokamak.

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With GROVER, a new large language model trained on human DNA, researchers could now attempt to decode the complex information hidden in our genome. GROVER treats human DNA as a text, learning its rules and context to draw functional information about the DNA sequences.

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Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy symptoms such as tissue swelling and inflammation. Now, researchers have discovered a hidden talent of mast cells: they can capture and use another type of immune cell called neutrophils. This surprising discovery sheds new light on how our immune system works, particularly during allergic reactions.

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The process by which phages -- viruses that infect and replicate within bacteria -- enter cells has been studied for over 50 years. In a new study, researchers have used cutting-edge techniques to look at this process at the level of a single cell.

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Researchers have unveiled a new loop heat pipe capable of transporting up to 10 kW of heat without using electric power. The loop heat pipe's design aims to contribute to energy savings and carbon neutrality in various fields, including waste heat recovery, solar heat utilization, electric vehicle thermal management, and data center cooling.

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Wild boars and red junglefowl gave rise to common pigs and chickens. These animals' genes evolved to express themselves differently, leading to signatures of domestication -- such as weaker bones and better viral resistance -- in pigs and chickens, according to a research team.