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Categories: Biology: Developmental, Chemistry: Thermodynamics
Published Cool roofs are best at beating cities' heat
(via sciencedaily.com) Original source Painting roofs white or covering them with a reflective coating would be more effective at cooling cities like London than vegetation-covered 'green roofs,' street-level vegetation or solar panels, finds a new study led by UCL researchers.
Published Researchers uncover key mechanisms in chromosome structure development
(via sciencedaily.com) Original source Researchers are making strides in understanding how chromosome structures change throughout the cell's life cycle.
Published A new breakthrough in understanding regeneration in a marine worm
(via sciencedaily.com) Original source The sea worm Platynereis dumerilii is only a few centimeters long but has a remarkable ability: in just a few days, it can regenerate entire parts of its body after an injury or amputation. By focusing more specifically on the mechanisms at play in the regeneration of this worm's tail, a research team has observed that gut cells play a role in the regeneration of the intestine as well as other tissues such as muscle and epidermis.
Published Research shows how RNA 'junk' controls our genes
(via sciencedaily.com) Original source Researchers have made a significant advance in understanding how genes are controlled in living organisms. The new study focuses on critical snippets of RNA in the tiny, transparent roundworm Caenorhabditis elegans (C. elegans). The study provides a detailed map of the 3'UTR regions of RNA in C. elegans. 3'UTRs (untranslated regions) are segments of RNA involved in gene regulation.
Published Researchers thwart resistant bacteria's strategy
(via sciencedaily.com) Original source Bacteria are experts at evolving resistance to antibiotics. One resistance strategy is to cover their cell walls in sticky and gooey biofilm that antibiotics cannot penetrate. A new discovery could put a stop to this strategy.
Published Scientists probe chilling behavior of promising solid-state cooling material
(via sciencedaily.com) Original source A research team has bridged a knowledge gap in atomic-scale heat motion. This new understanding holds promise for enhancing materials to advance an emerging technology called solid-state cooling.
Published Common plastics could passively cool and heat buildings with the seasons
(via sciencedaily.com) Original source By restricting radiant heat flows between buildings and their environment to specific wavelengths, coatings engineered from common materials can achieve energy savings and thermal comfort that goes beyond what traditional building envelopes can achieve.
Published Characterization of the extraordinary thermoelectric properties of cadmium arsenide thin films
(via sciencedaily.com) Original source If there's one thing we humans are good at, it's producing heat. Significant amounts, and in many cases most of the energy we generate and put into our systems we lose as heat, whether it be our appliances, our transportation, our factories, even our electrical grid.
Published New, holistic way to teach synthetic biology
(via sciencedaily.com) Original source Synthetic biology combines principles from science, engineering and social science, creating emerging technologies such as alternative meats and mRNA vaccines; Deconstructing synthetic biology across scales gives rise to new approach to uniting traditional disciplines; Case studies offer a modular, accessible approach to teaching at different institutions.
Published From takeoff to flight, the wiring of a fly's nervous system is mapped
(via sciencedaily.com) Original source Although a fly's motor neurons are few, it performs remarkable aerial and terrestrial feats. A wiring diagram recently created of the motor circuits in the central nervous system of the fruit fly is providing detailed information on how the nerve coordination of leg movements differs from that controlling the wings. Such studies reveal the unexpected complexity of the fly's tiny motor system. They also advance the understanding of how the central nervous system in animals coordinates individual muscles to carry out a variety of behaviors.
Published Cell division: Before commitment, a very long engagement
(via sciencedaily.com) Original source Before a cell commits fully to the process of dividing itself into two new cells, it may ensure the appropriateness of its commitment by staying for many hours -- sometimes more than a day -- in a reversible intermediate state, according to a new discovery. Their revelation of this fundamental feature of biology includes details of its mechanisms and dynamics, which may inform the development of future therapies targeting cancers and other diseases.
Published The on-and-off affair in DNA
(via sciencedaily.com) Original source Researchers have discovered that in thale cresses histone H3 lysine-9 (H3K9) methylation, conventionally thought to be a mark of turning off gene transcription, can also turn on gene expression via the interactions of two other proteins and histone marks. The molecular mechanisms demonstrate that rather than functioning as a simple 'off switch,' H3K9 methylation is more like a 'dimmer switch' that fine-tunes DNA transcription. The discovery suggests there might be similar mechanisms in other organisms, too.
Published Slipping a note to a neighbor: The cellular way
(via sciencedaily.com) Original source Study reveals how drug molecules bind in channels between neighboring cells, changing intercellular communication.
Published Small, adsorbent 'fins' collect humidity rather than swim through water
(via sciencedaily.com) Original source Clean, safe water is a limited resource and access to it depends on local bodies of water. But even dry regions have some water vapor in the air. To harvest small amounts of humidity, researchers developed a compact device with absorbent-coated fins that first trap moisture and then generate potable water when heated. They say the prototype could help meet growing demands for water, especially in arid locations.
Published Zebrafish reveal how bioelectricity shapes muscle development
(via sciencedaily.com) Original source New research describes how nerve cells and muscle cells communicate through electrical signals during development -- a phenomenon known as bioelectricity. The communication, which takes place via specialized channels between cells, is vital for proper development and behavior. The study identifies specific genes that control the process, and pins down what happens when it goes wrong. The finding offers clues to the genetic origins of muscle disorders in humans.
Published Discovery of vast sex differences in cellular activity has major implications for disease treatment
(via sciencedaily.com) Original source The study reveals vast differences in gene activity within the mitochondria of males compared to females. This is the first study to test effects of all 37 genes in the mitochondrial genome -- genes that copepods and humans share. The study found that males demonstrate more activity across all protein-coding mitochondrial genes than females. Although the study looks at tiny marine organisms called copepods, the findings have weighty implications for human medicine.
Published How cells boost gene expression
(via sciencedaily.com) Original source The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins -- yet it exists in large quantities. A research team has now discovered an important function of antisense RNA (asRNA): the researchers found that asRNA acts as a 'superhighway' in cell transport and thus accelerates gene expression.
Published How to make aging a 'fairer game' for all wormkind
(via sciencedaily.com) Original source Researchers have discovered a new fundamental mechanism governing the rules of ageing in worms. The researchers were able to manipulate the mechanism through genetic interventions which dramatically extend not just the lifespan of the worms, but also their health-span. In other words, trading weak, frail old age with vigorous golden years -- all without altering their diet, environment or other external factors.
Published Where to put head and tail?
(via sciencedaily.com) Original source Formation of the body axes is a critical part of embryonic development. They guarantee that all body parts end up where they belong and that no ears grow on our backs. The head-tail axis, for example, determines the orientation of the two ends of the body. It was previously assumed that this axis is largely determined by the interplay between the Nodal and BMP signals. However, there appears to be another player in this system, as researchers have now discovered by using an embryo-like model system they developed. In the absence of BMP, the signalling molecule beta-catenin takes on the role of the Nodal antagonist. This new mechanism could be a flexible solution for axis formation in embryos with different shapes.
Published The genetic 'switches' of bone growth
(via sciencedaily.com) Original source In mammals, only 3% of the genome consists of coding genes which, when transcribed into proteins, ensure the biological functions of the organism and the in-utero development of future individuals. But genes do not function alone. They are controlled by other sequences in the genome, called enhancers, which, like switches, activate or deactivate them as required. A team has now identified and located 2700 enhancers -- among millions of non-coding genetic sequences -- that precisely regulate the genes responsible for bone growth. This discovery sheds light on one of the major factors influencing the size of individuals in adulthood, and explains why their failure could be the cause of certain bone malformations.