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Categories: Biology: Developmental, Engineering: Biometric

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In a breakthrough for bioengineering, researchers have developed organoids that can model the human respiratory tract. The organoids, called AirGels, allow them to uncover the mechanism by which antibiotic-resistant pathogens like Pseudomonas aeruginosa infect the respiratory tract.

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Researchers have discovered new cell types in the visual system of flies, made possible by their creation of a tool that finds and labels neurons during development. The study combines single-cell sequencing data with a novel algorithm to identify pairs of genes that point to previously unknown cells in the brains of fruit flies.

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Scientists have pinpointed a genetic cause for virgin birth for the first time, and once switched on the ability is passed down through generations of females.

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Researchers have developed a pioneering technological solution that counterfeiters have no response to.

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Originally, the powerhouses of higher cells, the mitochondria, were independent organisms. Researchers have investigated to what extent their metabolism has blended with that of their host cells in the course of evolution, using the example of a mitochondrial stress response. They have discovered that mitochondria send two different biochemical signals. These are processed together in the cell and trigger a support mechanism to restore cellular balance (homeostasis).

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A metabolic by-product that is more prevalent during fasting may supercharge immune cells as they fight infection and disease, reports an early stage study. The findings may pave the way for future personalized dietary recommendations to augment treatments for infection, cancer and other diseases.

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Bees and wasps have converged on the same architectural solutions to nest-building problems, according to new research.

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In a step forward in the development of genetic medicines, researchers have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body. If translated into the clinic, this approach could expand access and reduce the cost of gene therapies for blood disorders, many of which currently require patients receive chemotherapy and a stem cell transplant.

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What happens inside the carnivorous plant Venus Flytrap when it catches an insect? New technology has led to discoveries about the electrical signalling that causes the trap to snap shut. Bioelectronic technology enables advanced research into how plants react to their surroundings, and to stress.

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The lifespan of a small roundworm that has been used as a key model organism in aging research is limited by how it self-sacrifices to feed its young, finds a new study.

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The results of a novel study has revealed exciting findings in the pursuit of an HIV cure.

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Researchers have identified a genetic sequence that is essential for plant reproduction. As this region is found in all plant species, it is expected to contribute to future crossbreeding initiatives and help solve the important problem of seed formation defects.

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Scientists have developed a new method to measure the smallest twists and torques of molecules within milliseconds. The method makes it possible to track the gene recognition of CRISPR-Cas protein complexes, also known as 'genetic scissors', in real time and with the highest resolution. With the data obtained, the recognition process can be accurately characterized and modeled to improve the precision of the genetic scissors.

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Warmer temperatures are known to make more turtle eggs become female hatchlings, but new research shows that those females also have a higher capacity for egg production, even before their sex is set. This finding may explain why many animals besides turtles have temperature-dependent sex determination and why the system persists, despite seeming like a risky strategy. It may also provide a troubling glimpse of what could lie ahead in a warming world.

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An obscure aquatic plant has helped to explain how plants avoid cracking up under the stresses and strains of growth.

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Engineers designed a technology to probe connections between the brain and the digestive tract. Using fibers embedded with a variety of sensors, as well as optogenetic stimulation, the researchers could control neural circuits connecting the gut and the brain, in mice.

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Researchers have outlined the structure and function of a protein complex which is required to repair damaged DNA and protect against cancer.

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Scientists have uncovered a new quality control system that removes damaged cells from early developing embryos.

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Researchers have used an unprecedented stem cell zoo to compare six different mammalian species and their developmental time.

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Genome Architecture Mapping captures complex, multi-way interactions in the genome. This is different than the workhorse technique of 3D genomics, which sees mostly two-way contacts, finds a new study.